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    SLC4A8 solute carrier family 4 member 8 [ Homo sapiens (human) ]

    Gene ID: 9498, updated on 3-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE.

    Cryo-EM structure of the sodium-driven chloride/bicarbonate exchanger NDCBE.
    Wang W, Tsirulnikov K, Zhekova HR, Kayık G, Khan HM, Azimov R, Abuladze N, Kao L, Newman D, Noskov SY, Zhou ZH, Pushkin A, Kurtz I., Free PMC Article

    10/23/2021
    The crystal structure at 2.8 A resolution of the regulatory N-terminal domain of human NDCBE represents the first crystal structure of an electroneutral sodium-bicarbonate cotransporter. The crystal structure forms an equivalent dimeric interface as observed for the cytoplasmic domain of Band 3, and thus establishes that the consensus motif VTVLP is the key minimal dimerization motif.

    The crystal structure of the regulatory domain of the human sodium-driven chloride/bicarbonate exchanger.
    Alvadia CM, Sommer T, Bjerregaard-Andersen K, Damkier HH, Montrasio M, Aalkjaer C, Morth JP., Free PMC Article

    07/20/2019
    This study confirmed the presence in human cDNA of mouse NDCBE-like transcripts (human NDCBE-A) and three novel transcripts NDCBE-C, NDCBE-D, and NDCBE-D'.

    Cloning and characterization of novel human SLC4A8 gene products encoding Na+-driven Cl-/HCO3(-) exchanger variants NDCBE-A, -C, and -D.
    Parker MD, Bouyer P, Daly CM, Boron WF., Free PMC Article

    01/21/2010
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