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    FPGT fucose-1-phosphate guanylyltransferase [ Homo sapiens (human) ]

    Gene ID: 8790, updated on 5-Mar-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    identified five amino acid residues that are critical for catalysis.

    Identification of catalytic amino acids in the human GTP fucose pyrophosphorylase active site.
    Quirk S, Seley KL.

    01/21/2010
    the nature of the purine base is the major determinant in substrate specificity, followed by the nature of the hexose-1-P, and finally by the ribose moiety. Binding is enthalpy-driven and does not involve proton transfer

    Substrate discrimination by the human GTP fucose pyrophosphorylase.
    Quirk S, Seley KL.

    01/21/2010
    A complete native data set has been collected as a first step in determining the three-dimensional structure of this enzyme.

    Purification, crystallization and preliminary X-ray characterization of the human GTP fucose pyrophosphorylase.
    Quirk S, Seley-Radtke KL., Free PMC Article

    01/21/2010
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