Amyloid Modifier SERF1a Accelerates Alzheimer's Amyloid-beta Fibrillization and Exacerbates the Cytotoxicity. | Amyloid Modifier SERF1a Accelerates Alzheimer's Amyloid-β Fibrillization and Exacerbates the Cytotoxicity. Tsai TY, Jhang WT, Hsu HK, Chan YT, Chang CF, Chen YR. | 02/15/2024 |
The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation. | The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation. Pras A, Houben B, Aprile FA, Seinstra R, Gallardo R, Janssen L, Hogewerf W, Gallrein C, De Vleeschouwer M, Mata-Cabana A, Koopman M, Stroo E, de Vries M, Louise Edwards S, Kirstein J, Vendruscolo M, Falsone SF, Rousseau F, Schymkowitz J, Nollen EAA., Free PMC Article | 12/18/2021 |
Inverse correlation was observed between SMN2, SERF1A and NAIP copy number polymorphism and spinal muscular atrophy type. | Joint effect of the SMN2 and SERF1A genes on childhood-onset types of spinal muscular atrophy in Serbian patients. Brkušanin M, Kosać A, Jovanović V, Pešović J, Brajušković G, Dimitrijević N, Todorović S, Romac S, Milić Rašić V, Savić-Pavićević D. | 06/28/2016 |
the autonomous amyloid-modifying activity of SERF1a observed in living organisms relies on a direct and dedicated manipulation of the early stages in the amyloid aggregation pathway. | SERF protein is a direct modifier of amyloid fiber assembly. Falsone SF, Meyer NH, Schrank E, Leitinger G, Pham CL, Fodero-Tavoletti MT, Holmberg M, Dulle M, Scicluna B, Gesslbauer B, Rückert HM, Wagner GE, Merle DA, Nollen EA, Kungl AJ, Hill AF, Cappai R, Zangger K., Free PMC Article | 03/2/2013 |
There is a close relationship between SMN2, NAIP and H4F5 gene copy number and spinal muscular atrophy disease severity | Correlation of SMN2, NAIP, p44, H4F5 and Occludin genes copy number with spinal muscular atrophy phenotype in Tunisian patients. Amara A, Adala L, Ben Charfeddine I, Mamaï O, Mili A, Lazreg TB, H'mida D, Amri F, Salem N, Boughammura L, Saad A, Gribaa M. | 06/16/2012 |
The human orthologs of MOAG-4, SERF2 and SERF1A, are ubiquitously expressed, consistent with a role in a general cellular pathway. | Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity. van Ham TJ, Holmberg MA, van der Goot AT, Teuling E, Garcia-Arencibia M, Kim HE, Du D, Thijssen KL, Wiersma M, Burggraaff R, van Bergeijk P, van Rheenen J, Jerre van Veluw G, Hofstra RM, Rubinsztein DC, Nollen EA. | 09/20/2010 |
Observational study of gene-disease association. (HuGE Navigator) | A population-based study of genotypic and phenotypic variability in children with spinal muscular atrophy. Arkblad E, Tulinius M, Kroksmark AK, Henricsson M, Darin N. | 02/11/2009 |