| METTL16 promotes osteosarcoma progression by downregulating VPS33B in an m[6] A-dependent manner. | METTL16 promotes osteosarcoma progression by downregulating VPS33B in an m(6) A-dependent manner.
Cheng J, Xu Z, Tan W, He J, Pan B, Zhang Y, Deng Y. | 03/15/2024 |
| METTL16 suppressed the proliferation and cisplatin-chemoresistance of bladder cancer by degrading PMEPA1 mRNA in a m6A manner through autophagy pathway. | METTL16 suppressed the proliferation and cisplatin-chemoresistance of bladder cancer by degrading PMEPA1 mRNA in a m6A manner through autophagy pathway.
Yu H, Zhuang J, Zhou Z, Song Q, Lv J, Yang X, Yang H, Lu Q., Free PMC Article | 02/26/2024 |
| Targeting key RNA methylation enzymes to improve the outcome of colorectal cancer chemotherapy (Review). | Targeting key RNA methylation enzymes to improve the outcome of colorectal cancer chemotherapy (Review).
Shao C, Han Y, Huang Y, Zhang Z, Gong T, Zhang Y, Tian X, Fang M, Han X, Li M., Free PMC Article | 02/26/2024 |
| METTL16 inhibits papillary thyroid cancer tumorigenicity through m[6]A/YTHDC2/SCD1-regulated lipid metabolism. | METTL16 inhibits papillary thyroid cancer tumorigenicity through m(6)A/YTHDC2/SCD1-regulated lipid metabolism.
Li Q, Wang Y, Meng X, Wang W, Duan F, Chen S, Zhang Y, Sheng Z, Gao Y, Zhou L., Free PMC Article | 02/16/2024 |
| METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation. | METTL16 promotes liver cancer stem cell self-renewal via controlling ribosome biogenesis and mRNA translation.
Xue M, Dong L, Zhang H, Li Y, Qiu K, Zhao Z, Gao M, Han L, Chan AKN, Li W, Leung K, Wang K, Pokharel SP, Qing Y, Liu W, Wang X, Ren L, Bi H, Yang L, Shen C, Chen Z, Melstrom L, Li H, Timchenko N, Deng X, Huang W, Rosen ST, Tian J, Xu L, Diao J, Chen CW, Chen J, Shen B, Chen H, Su R., Free PMC Article | 02/6/2024 |
| METTL16 Inhibits the Malignant Progression of Epithelial Ovarian Cancer through the lncRNA MALAT1/beta-Catenin Axis. | METTL16 Inhibits the Malignant Progression of Epithelial Ovarian Cancer through the lncRNA MALAT1/β-Catenin Axis.
Li C, Liu J, Lyu Y, Ling S, Luo Y., Free PMC Article | 11/21/2023 |
| The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression. | The RNA methyltransferase METTL16 enhances cholangiocarcinoma growth through PRDM15-mediated FGFR4 expression.
Liu N, Zhang J, Chen W, Ma W, Wu T., Free PMC Article | 11/2/2023 |
| Functional analysis of 3'-UTR hairpins supports a two-tiered model for posttranscriptional regulation of MAT2A by METTL16. | Functional analysis of 3'-UTR hairpins supports a two-tiered model for posttranscriptional regulation of MAT2A by METTL16.
Hunter OV, Ruiz JC, Flaherty JN, Conrad NK., | 10/28/2023 |
| METTL16 controls Kaposi's sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle. | METTL16 controls Kaposi's sarcoma-associated herpesvirus replication by regulating S-adenosylmethionine cycle.
Zhang X, Meng W, Feng J, Gao X, Qin C, Feng P, Huang Y, Gao SJ., Free PMC Article | 09/8/2023 |
| Genetic Variations Within METTL16 and Susceptibility to Sudden Cardiac Death in Chinese Populations With Coronary Artery Disease. | Genetic Variations Within METTL16 and Susceptibility to Sudden Cardiac Death in Chinese Populations With Coronary Artery Disease.
Zhen X, Zhao W, Wang J, Li L, He Y, Zhang J, Li C, Zhang S, Huang J, Luo B, Gao Y. | 08/4/2023 |
| METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression. | METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.
Wei W, Zhang ZY, Shi B, Cai Y, Zhang HS, Sun CL, Fei YF, Zhong W, Zhang S, Wang C, He B, Jiang GM, Wang H., Free PMC Article | 06/28/2023 |
| METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2. | METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2.
Wang F, Zhang J, Lin X, Yang L, Zhou Q, Mi X, Li Q, Wang S, Li D, Liu XM, Zhou J. | 04/7/2023 |
| METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism. | METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism.
Han L, Dong L, Leung K, Zhao Z, Li Y, Gao L, Chen Z, Xue J, Qing Y, Li W, Pokharel SP, Gao M, Chen M, Shen C, Tan B, Small A, Wang K, Zhang Z, Qin X, Yang L, Wunderlich M, Zhang B, Mulloy JC, Marcucci G, Chen CW, Wei M, Su R, Chen J, Deng X., Free PMC Article | 01/21/2023 |
| Elucidating the Kinetic Mechanism of Human METTL16. | Elucidating the Kinetic Mechanism of Human METTL16.
Breger K, Brown JA., Free PMC Article | 01/21/2023 |
| METTL16 epigenetically enhances GPX4 expression via m6A modification to promote breast cancer progression by inhibiting ferroptosis. | METTL16 epigenetically enhances GPX4 expression via m6A modification to promote breast cancer progression by inhibiting ferroptosis.
Ye F, Wu J, Zhang F. | 01/7/2023 |
| Clinical Significance of Methyltransferase-like 16 Expression in Epithelial Ovarian Cancer. | Clinical Significance of Methyltransferase-like 16 Expression in Epithelial Ovarian Cancer.
Li C, Qiao C, Ding H, Luo Y. | 12/17/2022 |
| METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma. | METTL16 antagonizes MRE11-mediated DNA end resection and confers synthetic lethality to PARP inhibition in pancreatic ductal adenocarcinoma.
Zeng X, Zhao F, Cui G, Zhang Y, Deshpande RA, Chen Y, Deng M, Kloeber JA, Shi Y, Zhou Q, Zhang C, Hou J, Kim W, Tu X, Yan Y, Xu Z, Chen L, Gao H, Guo G, Liu J, Zhu Q, Cao Y, Huang J, Wu Z, Zhu S, Yin P, Luo K, Mer G, Paull TT, Yuan J, Tao K, Lou Z. | 10/8/2022 |
| METTL16 promotes hepatocellular carcinoma progression through downregulating RAB11B-AS1 in an m(6)A-dependent manner. | METTL16 promotes hepatocellular carcinoma progression through downregulating RAB11B-AS1 in an m(6)A-dependent manner.
Dai YZ, Liu YD, Li J, Chen MT, Huang M, Wang F, Yang QS, Yuan JH, Sun SH., Free PMC Article | 06/11/2022 |
| RNA methyltransferase METTL16: Targets and function. | RNA methyltransferase METTL16: Targets and function.
Satterwhite ER, Mansfield KD., Free PMC Article | 05/7/2022 |
| METTL16 exerts an m(6)A-independent function to facilitate translation and tumorigenesis. | METTL16 exerts an m(6)A-independent function to facilitate translation and tumorigenesis.
Su R, Dong L, Li Y, Gao M, He PC, Liu W, Wei J, Zhao Z, Gao L, Han L, Deng X, Li C, Prince E, Tan B, Qing Y, Qin X, Shen C, Xue M, Zhou K, Chen Z, Xue J, Li W, Qin H, Wu X, Sun M, Nam Y, Chen CW, Huang W, Horne D, Rosen ST, He C, Chen J., Free PMC Article | 03/5/2022 |
| METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer. | METTL16 promotes cell proliferation by up-regulating cyclin D1 expression in gastric cancer.
Wang XK, Zhang YW, Wang CM, Li B, Zhang TZ, Zhou WJ, Cheng LJ, Huo MY, Zhang CH, He YL., Free PMC Article | 02/5/2022 |
| The pan-cancer analysis of the two types of uterine cancer uncovered clinical and prognostic associations with m6A RNA methylation regulators. | The pan-cancer analysis of the two types of uterine cancer uncovered clinical and prognostic associations with m6A RNA methylation regulators.
Zou Z, Zhou S, Liang G, Tang Z, Li K, Tan S, Zhang X, Zhu X. | 01/1/2022 |
| The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features. | The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features.
Covelo-Molares H, Obrdlik A, Poštulková I, Dohnálková M, Gregorová P, Ganji R, Potěšil D, Gawriyski L, Varjosalo M, Vaňáčová Š., Free PMC Article | 12/25/2021 |
| Systematic analysis of molecular characterization and clinical relevance of m6A regulators in digestive system pan-cancers. | Systematic analysis of molecular characterization and clinical relevance of m6A regulators in digestive system pan-cancers.
Kou T, Chai R, Jin L, Bai Z, Yang Y, Zhao Y, Wu D, Zhang Z, Yang Y., Free PMC Article | 12/4/2021 |
| Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima. | Enzymatic characterization of three human RNA adenosine methyltransferases reveals diverse substrate affinities and reaction optima.
Yu D, Kaur G, Blumenthal RM, Zhang X, Cheng X., Free PMC Article | 08/28/2021 |