STAT5 is essential for inducing the suppressive subset and attenuate cytotoxicity of Vdelta2[+] T cells in acute myeloid leukemia. | STAT5 is essential for inducing the suppressive subset and attenuate cytotoxicity of Vδ2(+) T cells in acute myeloid leukemia. Cheng C, Liang S, Yue K, Wu N, Li Z, Dong T, Dong X, Ling M, Jiang Q, Liu J, Huang XJ. | 03/28/2024 |
Abnormal M1 polarization of placental macrophage induced by IL-15/STAT5 activation in VVC may lead to adverse pregnancy outcomes. | Abnormal M1 polarization of placental macrophage induced by IL-15/STAT5 activation in VVC may lead to adverse pregnancy outcomes. Zhang Y, Zhao L, Wu A, Lin P, Fan J, Chen J, Wang X, Zeng X. | 02/1/2024 |
A novel EGFR variant EGFRx maintains glioblastoma stem cells through STAT5. | A novel EGFR variant EGFRx maintains glioblastoma stem cells through STAT5. Huang W, Li J, Zhu H, Qin X, Chen C, Wang B, Wei J, Song Y, Lu X, Li Z, Xia W, He A, Cheng L, Yu X, Shu K, Wang W., | 01/9/2024 |
Dual inhibition of STAT3 and STAT5 may overcome imatinib resistance in chronic myeloid leukemia. | Dual inhibition of STAT3 and STAT5 may overcome imatinib resistance in chronic myeloid leukemia. Yin L, Xu J, Wu W, Niu M, Li Z, Zhu F, Xu K. | 06/28/2023 |
Stat5 inhibits NLRP3-mediated pyroptosis to enhance chemoresistance of breast cancer cells via promoting miR-182 transcription. | Stat5 inhibits NLRP3-mediated pyroptosis to enhance chemoresistance of breast cancer cells via promoting miR-182 transcription. Wan P, He X, Han Y, Wang L, Yuan Z. | 06/16/2023 |
Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of TH9 cells to promote allergic inflammation. | Dynamic chromatin accessibility licenses STAT5- and STAT6-dependent innate-like function of T(H)9 cells to promote allergic inflammation. Son A, Meylan F, Gomez-Rodriguez J, Kaul Z, Sylvester M, Falduto GH, Vazquez E, Haque T, Kitakule MM, Wang C, Manthiram K, Qi CF, Cheng J, Gurram RK, Zhu J, Schwartzberg P, Milner JD, Frischmeyer-Guerrerio PA, Schwartz DM., Free PMC Article | 06/5/2023 |
STAT5A modulates gastric cancer progression via upregulation of CD44. | STAT5A modulates gastric cancer progression via upregulation of CD44. Wang S, Fan R, Gao H, Ma X, Wu Y, Xing Y, Wang Y, Jia Y. | 05/28/2023 |
STAT5b: A master regulator of key biological pathways. | STAT5b: A master regulator of key biological pathways. Smith MR, Satter LRF, Vargas-Hernández A., Free PMC Article | 02/13/2023 |
STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential. | STAT5 confers lactogenic properties in breast tumorigenesis and restricts metastatic potential. Lin M, Ku AT, Dong J, Yue F, Jiang W, Ibrahim AA, Peng F, Creighton CJ, Nagi C, Gutierrez C, Rosen JM, Zhang XH, Hilsenbeck SG, Chen X, Du YN, Huang S, Shi A, Fan Z, Li Y., Free PMC Article | 12/3/2022 |
Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases. | Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases. Kim U, Shin HY., Free PMC Article | 10/22/2022 |
PDGFRbeta promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma. | PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma. Garces de Los Fayos Alonso I, Zujo L, Wiest I, Kodajova P, Timelthaler G, Edtmayer S, Zrimšek M, Kollmann S, Giordano C, Kothmayer M, Neubauer HA, Dey S, Schlederer M, Schmalzbauer BS, Limberger T, Probst C, Pusch O, Högler S, Tangermann S, Merkel O, Schiefer AI, Kornauth C, Prutsch N, Zimmerman M, Abraham B, Anagnostopoulos J, Quintanilla-Martinez L, Mathas S, Wolf P, Stoiber D, Staber PB, Egger G, Klapper W, Woessmann W, Look TA, Gunning P, Turner SD, Moriggl R, Lagger S, Kenner L., Free PMC Article | 09/24/2022 |
miR-10 and Its Negative Correlation with Serum IL-35 Concentration and Positive Correlation with STAT5a Expression in Patients with Rheumatoid Arthritis. | miR-10 and Its Negative Correlation with Serum IL-35 Concentration and Positive Correlation with STAT5a Expression in Patients with Rheumatoid Arthritis. Paradowska-Gorycka A, Wajda A, Rzeszotarska E, Kmiolek T, Stypinska B, Dudek E, Romanowska-Prochnicka K, Syrowka P., Free PMC Article | 08/6/2022 |
Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjogren's syndrome. | Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in Sjögren's syndrome. Keindl M, Davies R, Bergum B, Brun JG, Hammenfors D, Jonsson R, Lyssenko V, Appel S., Free PMC Article | 05/14/2022 |
STAT5A modulates CDYL2/SLC7A6 pathway to inhibit the proliferation and invasion of hepatocellular carcinoma by targeting to mTORC1. | STAT5A modulates CDYL2/SLC7A6 pathway to inhibit the proliferation and invasion of hepatocellular carcinoma by targeting to mTORC1. Chen X, Wang Z, Zhao X, Zhang L, Zhou L, Li X, Ge C, Zhao F, Chen T, Xie H, Cui Y, Tian H, Li H, Yao M, Li J. | 05/7/2022 |
YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis. | YTHDF2 promotes multiple myeloma cell proliferation via STAT5A/MAP2K2/p-ERK axis. Hua Z, Wei R, Guo M, Lin Z, Yu X, Li X, Gu C, Yang Y. | 04/23/2022 |
miR27a, a fine-tuning molecule, interacts with growth hormone (GH) signaling and ornithine decarboxylase (ODC) via targeting STAT5. | miR27a, a fine-tuning molecule, interacts with growth hormone (GH) signaling and ornithine decarboxylase (ODC) via targeting STAT5. Coker-Gurkan A, Koyuncu K, Yerlikaya PO, Arisan ED. | 04/16/2022 |
STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment. | STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment. Jesser EA, Brady NJ, Huggins DN, Witschen PM, O'Connor CH, Schwertfeger KL., Free PMC Article | 03/5/2022 |
Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma. | Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma. Xie J, Wang Z, Fan W, Liu Y, Liu F, Wan X, Liu M, Wang X, Zeng D, Wang Y, He B, Yan M, Zhang Z, Zhang M, Hou Z, Wang C, Kang Z, Fang W, Zhang L, Lam EW, Guo X, Yan J, Zeng Y, Chen M, Liu Q., Free PMC Article | 03/5/2022 |
OSMRbeta mutants enhance basal keratinocyte differentiation via inactivation of the STAT5/KLF7 axis in PLCA patients. | OSMRβ mutants enhance basal keratinocyte differentiation via inactivation of the STAT5/KLF7 axis in PLCA patients. Liu J, Chen J, Zhong Y, Yu X, Lu P, Feng J, Zhang X, Ma S, Yang C, Yang B, Rong Z., Free PMC Article | 01/29/2022 |
Aberrantly low STAT3 and STAT5 responses are associated with poor outcome and an inflammatory gene expression signature in pediatric acute myeloid leukemia. | Aberrantly low STAT3 and STAT5 responses are associated with poor outcome and an inflammatory gene expression signature in pediatric acute myeloid leukemia. Narayanan P, Man TK, Gerbing RB, Ries R, Stevens AM, Wang YC, Long X, Gamis AS, Cooper T, Meshinchi S, Alonzo TA, Redell MS., Free PMC Article | 01/1/2022 |
[Hsa_circ_0005221 promotes prostate cancer progression through the miR-339-5p/STAT5a pathway]. | [Hsa_circ_0005221 promotes prostate cancer progression through the miR-339-5p/STAT5a pathway]. Chen SS, Zhang YW, Wang YL, Gao Y, Wang C, Hu Q, Wu TG, Tao SC, Zhao JX, Chen M. | 12/25/2021 |
Staphylococcus aureus Induces Signal Transducer and Activator of Transcription 5Dependent miR-155 Expression in Cutaneous T-Cell Lymphoma. | Staphylococcus aureus Induces Signal Transducer and Activator of Transcription 5‒Dependent miR-155 Expression in Cutaneous T-Cell Lymphoma. Willerslev-Olsen A, Gjerdrum LMR, Lindahl LM, Buus TB, Pallesen EMH, Gluud M, Bzorek M, Nielsen BS, Kamstrup MR, Rittig AH, Bonefeld CM, Krejsgaard T, Geisler C, Koralov SB, Litman T, Becker JC, Woetmann A, Iversen L, Odum N. | 12/18/2021 |
Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA-23a-AKT signaling in hepatocellular carcinoma. | Loss of STAT5A promotes glucose metabolism and tumor growth through miRNA-23a-AKT signaling in hepatocellular carcinoma. Jiang Y, Tao Y, Zhang X, Wei X, Li M, He X, Zhou B, Guo W, Yin H, Cheng S., Free PMC Article | 11/27/2021 |
Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer. | Serine residues 726 and 780 have nonredundant roles regulating STAT5a activity in luminal breast cancer. Woock AE, Grible JM, Olex AL, Harrell JC, Zot P, Idowu M, Clevenger CV., Free PMC Article | 11/6/2021 |
Therapeutic delivery of siRNA with polymeric carriers to down-regulate STAT5A expression in high-risk B-cell acute lymphoblastic leukemia (B-ALL). | Therapeutic delivery of siRNA with polymeric carriers to down-regulate STAT5A expression in high-risk B-cell acute lymphoblastic leukemia (B-ALL). Mohseni M, Kucharski C, K C RB, Nasrullah M, Jiang X, Uludağ H, Brandwein J., Free PMC Article | 10/30/2021 |