| Impact of miR-519d on the Biological Activity of Non-Small Cell Lung Cancer Cells and Its Mechanism. | Impact of miR-519d on the Biological Activity of Non-Small Cell Lung Cancer Cells and Its Mechanism.
Wang K, Zhao X, Liu S, Xu S. | 02/5/2024 |
| Transcription factor p53-mediated activation of miR-519d-3p and downregulation of E2F1 attenuates prostate cancer growth and metastasis. | Transcription factor p53-mediated activation of miR-519d-3p and downregulation of E2F1 attenuates prostate cancer growth and metastasis.
Zhang D, Yang XJ, Luo QD, Xue L, Chong T. | 07/23/2022 |
| Identification and validation of aging-related genes in COPD based on bioinformatics analysis. | Identification and validation of aging-related genes in COPD based on bioinformatics analysis.
Zhong S, Yang L, Liu N, Zhou G, Hu Z, Chen C, Wang Y., Free PMC Article | 07/2/2022 |
| Downregulation of miR-519d-3p is Associated with Poor Outcomes and Facilitates Tumor Progression in Papillary Thyroid Cancer by Regulating FOXQ1. | Downregulation of miR-519d-3p is Associated with Poor Outcomes and Facilitates Tumor Progression in Papillary Thyroid Cancer by Regulating FOXQ1.
Li P, Pan X, Zheng Z, Sun Y, Han Y, Dong J, Lu M. | 01/22/2022 |
| circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells. | circ_0007385 served as competing endogenous RNA for miR-519d-3p to suppress malignant behaviors and cisplatin resistance of non-small cell lung cancer cells.
Ye Y, Zhao L, Li Q, Xi C, Li Y, Li Z., Free PMC Article | 08/14/2021 |
| H19 promotes aerobic glycolysis, proliferation, and immune escape of gastric cancer cells through the microRNA-519d-3p/lactate dehydrogenase A axis. | H19 promotes aerobic glycolysis, proliferation, and immune escape of gastric cancer cells through the microRNA-519d-3p/lactate dehydrogenase A axis.
Sun L, Li J, Yan W, Yao Z, Wang R, Zhou X, Wu H, Zhang G, Shi T, Chen W., Free PMC Article | 06/19/2021 |
| miR519d3p/HIF2alpha axis increases the chemosensitivity of human cervical cancer cells to cisplatin via inactivation of PI3K/AKT signaling. | miR‑519d‑3p/HIF‑2α axis increases the chemosensitivity of human cervical cancer cells to cisplatin via inactivation of PI3K/AKT signaling.
Jiang L, Shi S, Li F, Shi Q, Zhong T, Zhang H, Xia Y. | 05/15/2021 |
| Circular noncoding RNA circMBOAT2 is a novel tumor marker and regulates proliferation/migration by sponging miR-519d-3p in colorectal cancer. | Circular noncoding RNA circMBOAT2 is a novel tumor marker and regulates proliferation/migration by sponging miR-519d-3p in colorectal cancer.
Tang X, Sun G, He Q, Wang C, Shi J, Gao L, Ye J, Liang Y, Qu H., Free PMC Article | 03/28/2021 |
| MiR-519d targets HER3 and can be used as a potential serum biomarker for non-small cell lung cancer. | MiR-519d targets HER3 and can be used as a potential serum biomarker for non-small cell lung cancer.
Wang A, Zhang H, Wang J, Zhang S, Xu Z., Free PMC Article | 02/27/2021 |
| Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/beta-catenin signaling pathway via regulating miR-519d-3p. | Down-regulation of lncRNA BLACAT1 inhibits ovarian cancer progression by suppressing the Wnt/β-catenin signaling pathway via regulating miR-519d-3p.
Yang H, Qi Y, Wang XL, Gu JJ, Shi TM. | 10/24/2020 |
| Long noncoding RNA PVT1 promotes laryngeal squamous cell carcinoma development by acting as a molecular sponge to regulate miR-519d-3p. | Long noncoding RNA PVT1 promotes laryngeal squamous cell carcinoma development by acting as a molecular sponge to regulate miR-519d-3p.
Zheng X, Zhao K, Liu T, Liu L, Zhou C, Xu M. | 06/20/2020 |
| Cyclin D1 (CCND1) was predicted and confirmed as the direct target genes of miR-519d-3p using luciferase report assay. In addition, knockdown of CCND1 imitated the suppressive effects of miR-519d-3p on cell proliferation and cell cycle progression | MicroRNA-519d-3p inhibits cell proliferation and cell cycle G1/S transition in glioma by targeting CCND1.
Ma L, Li J. | 03/7/2020 |
| It was noted that BAMBI is a target of miR519d3p and miR519d3p promotes transforming growth factor beta/mothers against decapentaplegic homolog 9mediated postoperative epidural scar formation via suppression of BAMBI. | miR‑519d‑3p promotes TGFβ/Smad mediated postoperative epidural scar formation via suppression of BAMBI.
Yang L, Gao Q, Lv F, Guo M, Zhao D. | 02/22/2020 |
| MiR519D inhibits the expression of CCND1 and plays a role in alleviating 5-fluorouracil resistance in colorectal cancer cells. | MiR-519d reduces the 5-fluorouracil resistance in colorectal cancer cells by down-regulating the expression of CCND1.
Huang R, Lin JY, Chi YJ. | 11/9/2019 |
| our results concluded that CASC9 promotes STAT3 expression via sponging miR-519d, in return, STAT3 activate CASC9 transcription, forming a positive feedback loop of CASC9/miR-519d/STAT3. The novel finding provides a potential therapeutic target for glioma. | Long noncoding RNA CASC9/miR-519d/STAT3 positive feedback loop facilitate the glioma tumourigenesis.
Liu H, Li C, Yang J, Sun Y, Zhang S, Yang J, Yang L, Wang Y, Jiao B., Free PMC Article | 11/2/2019 |
| miR-519d overexpression dramatically suppressed MCF-7 cells proliferation, migration and invasion. While downregulation of miR-519d by miR-519d inhibitor substantially increased MCF-7 cell carcinogenesis. | MiR-519d suppresses breast cancer tumorigenesis and metastasis via targeting MMP3.
Chu C, Liu X, Bai X, Zhao T, Wang M, Xu R, Li M, Hu Y, Li W, Yang L, Qin Y, Yang M, Yan C, Zhang Y., Free PMC Article | 04/13/2019 |
| A significant functional role for miR-519d in determining EphA4 expression and melanoma progression. | miR-519d Promotes Melanoma Progression by Downregulating EphA4.
Hua KT, Hong JB, Sheen YS, Huang HY, Huang YL, Chen JS, Liao YH. | 11/10/2018 |
| Results show that miR-519d expression was significantly downregulated in hypertrophic scar tissues and fibroblasts. | MicroRNA-519d inhibits proliferation and induces apoptosis of human hypertrophic scar fibroblasts through targeting Sirtuin 7.
Zhou X, Xie Y, Xiao H, Deng X, Wang Y, Jiang L, Liu C, Zhou R. | 10/6/2018 |
| Overexpression of miR-519d-3p can inhibit the proliferation of prostate cancer cells. The possible mechanism is that miR-519d-3p inhibits the expression of TRAF4. | [Overexpression of miR-519d-3p inhibits the proliferation of DU-145 prostate cancer cells by reducing TRAF4].
Li X, Han X, Yang J, Sun J, Wei P. | 09/22/2018 |
| findings suggest that miR-519d-3p regulates the LIMK1/CFL1 pathway in breast cancer | MiR-519d-3p suppresses breast cancer cell growth and motility via targeting LIM domain kinase 1.
Li D, Song H, Wu T, Xie D, Hu J, Zhao J, Shen Q, Fang L. | 07/28/2018 |
| Results showed that miR-519d-3p was downregulated in gastric cancer (GC) tissues and was associated with the clinical stage and lymph node metastasis of GC tissues. The study demonstrated that miR-519d-3p functions as a tumor suppressor by targeting and downregulating the expression of BCL6 in GC cells. | miR-519d-3p Inhibits Cell Proliferation and Invasion of Gastric Cancer by Downregulating B-Cell Lymphoma 6.
Li YY, Shao JP, Zhang SP, Xing GQ, Liu HJ., Free PMC Article | 04/21/2018 |
| In this review, we focus on the function of miR-519d in placental trophoblasts, where miR-519d regulates cell migration and invasion, and its aberrant expression is associated with preeclampsia. | The function of miR-519d in cell migration, invasion, and proliferation suggests a role in early placentation.
Xie L, Sadovsky Y., Free PMC Article | 12/23/2017 |
| Low mir519d expression is associated with cisplatin-resistance in breast cancer. | MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1.
Xie Q, Wang S, Zhao Y, Zhang Z, Qin C, Yang X., Free PMC Article | 10/14/2017 |
| E2F transcription factor 1 (E2F1) downregulated micrRNA miR-519d directly and miR-519d downregulated Ras homolog gene family member C (RhoC) directly. | E2F-1 targets miR-519d to regulate the expression of the ras homolog gene family member C.
Sang XB, Zong ZH, Wang LL, Wu DD, Chen S, Liu BL, Zhao Y., Free PMC Article | 08/19/2017 |
| Study showed low expression level of miR-519d associated with TNM staging and metastasis of breast cancer, and suggested it as a tumor suppressor with role in breast cancer cell proliferation and invasion by downregulating STAT3. | miR-519d-mediated downregulation of STAT3 suppresses breast cancer progression.
Deng X, Zhao Y, Wang B. | 05/28/2016 |