| Replication stress causes delayed mitotic entry and chromosome 12 fragility at the ANKS1B large neuronal gene in human induced pluripotent stem cells. | Replication stress causes delayed mitotic entry and chromosome 12 fragility at the ANKS1B large neuronal gene in human induced pluripotent stem cells.
Kislova AV, Zheglo D, Pozhitnova VO, Sviridov PS, Gadzhieva EP, Voronina ES. | 08/22/2023 |
| Regulation of transforming growth factor-beta1 by circANKS1B/miR-515-5p affects the metastatic potential and cisplatin resistance in oral squamous cell carcinoma. | Regulation of transforming growth factor-beta1 by circANKS1B/miR-515-5p affects the metastatic potential and cisplatin resistance in oral squamous cell carcinoma.
Yan J, Xu H., Free PMC Article | 02/19/2022 |
| Circular RNA circANKS1B acts as a sponge for miR-152-3p and promotes prostate cancer progression by upregulating TGF-alpha expression. | Circular RNA circANKS1B acts as a sponge for miR-152-3p and promotes prostate cancer progression by upregulating TGF-α expression.
Tao LJ, Pan XY, Wang JW, Zhang L, Tao LS, Liang CZ. | 08/21/2021 |
| Study describe monogenic copy-number variations in ANKS1B in individuals that display a previously undefined spectrum of neurodevelopmental phenotypes that authors term ANKS1B haploinsufficiency syndrome. | Haploinsufficiency in the ANKS1B gene encoding AIDA-1 leads to a neurodevelopmental syndrome.
Carbonell AU, Cho CH, Tindi JO, Counts PA, Bates JC, Erdjument-Bromage H, Cvejic S, Iaboni A, Kvint I, Rosensaft J, Banne E, Anagnostou E, Neubert TA, Scherer SW, Molholm S, Jordan BA., Free PMC Article | 12/14/2019 |
| Our data uncover an essential role of the novel circular RNA circANKS1B in the metastasis of breast cancer, which demonstrate that therapeutic targeting of circANKS1B may better prevent breast cancer metastasis. | The pro-metastasis effect of circANKS1B in breast cancer.
Zeng K, He B, Yang BB, Xu T, Chen X, Xu M, Liu X, Sun H, Pan Y, Wang S., Free PMC Article | 04/27/2019 |
| this is the first genetic association study of the relationship between the rs7968606 SNP of ANKS1B and the response of schizophrenia patients to treatment with amisulpride. | rs7968606 polymorphism of ANKS1B is associated with improvement in the PANSS general score of schizophrenia caused by amisulpride.
Kang SG, Chee IS, Lee K, Lee J. | 12/30/2017 |
| We provide the first evidence that ANKS1B expression is down regulated in ccRCC tumors relative to patient-matched normal kidney tissue in smokers. | ANKS1B is a smoking-related molecular alteration in clear cell renal cell carcinoma.
Eckel-Passow JE, Serie DJ, Bot BM, Joseph RW, Cheville JC, Parker AS., Free PMC Article | 08/30/2014 |
| AIDA1 PTB domain binds amyloid protein precursorin a similar manner to the X11/Mint PTB domain. | Solution structure and peptide binding of the PTB domain from the AIDA1 postsynaptic signaling scaffolding protein.
Smirnova E, Shanbhag R, Kurabi A, Mobli M, Kwan JJ, Donaldson LW., Free PMC Article | 02/1/2014 |
| Targeted-E2A-PBX1 inhibition leads to reduced expression of the EB-1 and Wnt16b genes; aberrant expression of these genes may be a key step in leukemogenesis in t(1;19)-positive pre-B leukemia. | The effects of siRNA-mediated inhibition of E2A-PBX1 on EB-1 and Wnt16b expression in the 697 pre-B leukemia cell line.
Casagrande G, te Kronnie G, Basso G. | 01/25/2012 |
| It is clear that some single-nucleotide polymorphisms and haplotypes of the EB-1 gene are associated with genetic difference between diabetic patients with and without nephropathy. | The genetic background difference between diabetic patients with and without nephropathy in a Taiwanese population by linkage disequilibrium mapping using 382 autosomal STR markers.
Pei D, Huang YJ, Hsieh CH, Kuo SW, Liou YH, Wu LS, Pei D, Huang YJ, Hsieh CH, Kuo SW, Liou YH, Wu LS. | 10/23/2010 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesThe genetic background difference between diabetic patients with and without nephropathy in a Taiwanese population by linkage disequilibrium mapping using 382 autosomal STR markers.
Pei D, Huang YJ, Hsieh CH, Kuo SW, Liou YH, Wu LS, Pei D, Huang YJ, Hsieh CH, Kuo SW, Liou YH, Wu LS. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium. | 09/15/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study and genome-wide association study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Detecting Genes and Gene-gene Interactions for Age-related Macular Degeneration with a Forest-based Approach.
Wang M, Zhang M, Chen X, Zhang H., Free PMC Article | 06/30/2010 |
| EB1 recognizes the nucleotide state of tubulin in the microtubule lattice | EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.
Zanic M, Stear JH, Hyman AA, Howard J., Free PMC Article | 03/15/2010 |
| The basic nuclear import signal for AIDA-1 is buried at the interface between the two sterile alpha motif domains. | A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import.
Kurabi A, Brener S, Mobli M, Kwan JJ, Donaldson LW. | 01/21/2010 |
| The TCR gene rearrangements in childhood B-lineage acute lymphoblastic leukemia was associated with expression of E2A-Pbx1 fusion protein chimeric oncogene. | The incidence of T-cell receptor gene rearrangements in childhood B-lineage acute lymphoblastic leukemia is related to immunophenotype and fusion oncogene expression.
Meleshko AN, Belevtsev MV, Savitskaja TV, Potapnev MP. | 01/21/2010 |
| Amyloid beta-protein precursor expression and secretion are regulated via activation of ERK1/2 by HGF in cells transfected with APP751. | Regulation of amyloid precursor protein expression and secretion via activation of ERK1/2 by hepatocyte growth factor in HEK293 cells transfected with APP751.
Liu F, Su Y, Li B, Ni B. | 01/21/2010 |
| Evidence pertaining to leukemogenesis by the well-characterized E2A-fusion protein E2A-PBX1 is reviewed and its mechanistic implications are considered. | E2A basic helix-loop-helix transcription factors in human leukemia.
LeBrun DP. | 01/21/2010 |
| specific EB-1/AIDA-1 isoforms, such as AIDA-1c, may participate in the regulation of nucleoplasmic coilin protein interactions in neuronal and transformed cells | A novel EB-1/AIDA-1 isoform, AIDA-1c, interacts with the Cajal body protein coilin.
Xu H, Hebert MD., Free PMC Article | 01/21/2010 |
| site-specific translocation and evidence of postnatal origin of the t(1;19) fusion in childhood acute lymphoblastic leukemia | Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.
Wiemels JL, Leonard BC, Wang Y, Segal MR, Hunger SP, Smith MT, Crouse V, Ma X, Buffler PA, Pine SR., Free PMC Article | 01/21/2010 |
| AbetaPP and the AIDA-1 proteins interact in vitro, in living cells and, endogenously, in leukemia cell lines;AIDA-1 proteins are expressed at high levels in the brain | The intracellular localization of amyloid beta protein precursor (AbetaPP) intracellular domain associated protein-1 (AIDA-1) is regulated by AbetaPP and alternative splicing.
Ghersi E, Vito P, Lopez P, Abdallah M, D'Adamio L. | 01/21/2010 |
| the interaction between AbetaPP and AIDA-1 is regulated by alternative splicing of the AIDA-1 protein | Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner.
Ghersi E, Noviello C, D'Adamio L. | 01/21/2010 |