| Conformational Change of the Hairpin-like-structured Robo2 Ectodomain Allows NELL1/2 Binding. | Conformational Change of the Hairpin-like-structured Robo2 Ectodomain Allows NELL1/2 Binding.
Miyaguchi M, Nakanishi Y, Maturana AD, Mizutani K, Niimi T. | 10/1/2022 |
| NELL2 modulates cell proliferation and apoptosis via ERK pathway in the development of benign prostatic hyperplasia. | NELL2 modulates cell proliferation and apoptosis via ERK pathway in the development of benign prostatic hyperplasia.
Liu J, Liu D, Zhang X, Li Y, Fu X, He W, Li M, Chen P, Zeng G, DiSanto ME, Wang X, Zhang X. | 11/27/2021 |
| Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2. | Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel-like proteins 1 and 2.
Pan R, Lu Q, Ren C, Li H, Zeng F, Tian X, Chen H., Free PMC Article | 07/31/2021 |
| results suggest that Robo2 functions as a receptor for NELL1/2, particularly under circumstances where Robo2 undergoes proteolytic digestion | Robo2 contains a cryptic binding site for neural EGFL-like (NELL) protein 1/2.
Yamamoto N, Kashiwagi M, Ishihara M, Kojima T, Maturana AD, Kuroda S, Niimi T., Free PMC Article | 12/14/2019 |
| CSF NELL2 is a potential diagnostic biomarker for TBM. | iTRAQ-based quantitative proteomic analysis of cerebrospinal fluid reveals NELL2 as a potential diagnostic biomarker of tuberculous meningitis.
Yang Y, Mu J, Chen G, Zhan Y, Zhong J, Wei Y, Cheng K, Qin B, You H, Xie P. | 12/19/2015 |
| CpG islands in the NELL1 and NELL2 promoters are hypermethylated in renal cell carcinoma.NELL1 and NELL2 protein expression is downregulated in clear cell renal carcinoma. | Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma.
Nakamura R, Oyama T, Tajiri R, Mizokami A, Namiki M, Nakamoto M, Ooi A., Free PMC Article | 08/29/2015 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |