Midkine (MDK) in Hepatocellular Carcinoma: More than a Biomarker. | Midkine (MDK) in Hepatocellular Carcinoma: More than a Biomarker. Christou C, Stylianou A, Gkretsi V., Free PMC Article | 02/9/2024 |
Elevated Midkine Serum Levels Are Associated with Long-Term Survival in Critically Ill Patients. | Elevated Midkine Serum Levels Are Associated with Long-Term Survival in Critically Ill Patients. Hohlstein P, Abu Jhaisha S, Yagmur E, Wawer D, Pollmanns MR, Adams JK, Wirtz TH, Brozat JF, Bündgens L, Hamesch K, Weiskirchen R, Tacke F, Trautwein C, Koch A., Free PMC Article | 01/16/2024 |
Single-cell RNA-sequencing analysis reveals enhanced non-canonical neurotrophic factor signaling in the subacute phase of traumatic brain injury. | Single-cell RNA-sequencing analysis reveals enhanced non-canonical neurotrophic factor signaling in the subacute phase of traumatic brain injury. Qiu X, Guo Y, Liu MF, Zhang B, Li J, Wei JF, Li M., Free PMC Article | 11/28/2023 |
Midkine characterization in human ovaries: potential new variants in follicles. | Midkine characterization in human ovaries: potential new variants in follicles. Cadenas J, Pors SE, Hansen CP, Olufsen SM, Subiran C, Bøtkjær JA, La Cour Poulsen L, Fedder J, Dueholm M, Colmorn LB, Kristensen SG, Mamsen LS, Andersen CY. | 11/22/2023 |
Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs. | Differential Production of Midkine and Pleiotrophin by Innate APCs upon Stimulation through Nucleic Acid-Sensing TLRs. Said EA, Al-Dughaishi S, Al-Hatmi W, Al-Reesi I, Al-Balushi MS, Al-Bimani A, Al-Busaidi JZ, Al-Riyami M, Al-Khabori M, Al-Kindi S, Procopio FA, Al-Sinawi S, Al-Ansari A, Koh CY, Al-Naamani K, Al-Jabri AA., Free PMC Article | 10/30/2023 |
Secreted proteins MDK, WFDC2, and CXCL14 as candidate biomarkers for early diagnosis of lung adenocarcinoma. | Secreted proteins MDK, WFDC2, and CXCL14 as candidate biomarkers for early diagnosis of lung adenocarcinoma. Li J, Li J, Hao H, Lu F, Wang J, Ma M, Jia B, Zhuo M, Wang J, Chi Y, Zhai X, Wang Y, Wu M, An T, Zhao J, Yang F, Wang Z., Free PMC Article | 02/4/2023 |
Long noncoding RNA HOTAIR and Midkine as biomarkers in thyroid cancer. | Long noncoding RNA HOTAIR and Midkine as biomarkers in thyroid cancer. Mahmoud AA, Mohamed HO, Abdel Aal AM, Abdelghafour HS, Jabir MA. | 01/11/2023 |
CAF-derived midkine promotes EMT and cisplatin resistance by upregulating lncRNA ST7-AS1 in gastric cancer. | CAF-derived midkine promotes EMT and cisplatin resistance by upregulating lncRNA ST7-AS1 in gastric cancer. Yang KD, Wang Y, Zhang F, Li QL, Luo BH, Feng DY, Zeng ZJ. | 11/5/2022 |
Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment. | Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment. Tang Y, Kwiatkowski DJ, Henske EP., Free PMC Article | 09/3/2022 |
Midkine Promotes Metastasis and Therapeutic Resistance via mTOR/RPS6 in Uveal Melanoma. | Midkine Promotes Metastasis and Therapeutic Resistance via mTOR/RPS6 in Uveal Melanoma. Karg MM, John L, Refaian N, Buettner C, Rottmar T, Sommer J, Bock B, Resheq YJ, Ksander BR, Heindl LM, Mackensen A, Bosch JJ. | 08/13/2022 |
Extracellular vesicles derived from pancreatic cancer cells are enriched in the growth factor Midkine. | Extracellular vesicles derived from pancreatic cancer cells are enriched in the growth factor Midkine. Casari I, Emmanouilidi A, Domenichini A, Falasca M. | 04/16/2022 |
Maternal serum midkine level increases in pregnant women with diabetes mellitus: a case-control study. | Maternal serum midkine level increases in pregnant women with diabetes mellitus: a case-control study. Oluklu D, Menekse Beser D, Uyan Hendem D, Sinaci S, Turgut E, Yazihan N, Sahin D. | 04/9/2022 |
Midkine promotes breast cancer cell proliferation and migration by upregulating NR3C1 expression and activating the NF-kappaB pathway. | Midkine promotes breast cancer cell proliferation and migration by upregulating NR3C1 expression and activating the NF-κB pathway. Zhang L, Song L, Xu Y, Xu Y, Zheng M, Zhang P, Wang Q. | 04/9/2022 |
Diagnostic performance of Midkine ratios in fine-needle aspirates for evaluation of Cytologically indeterminate thyroid nodules. | Diagnostic performance of Midkine ratios in fine-needle aspirates for evaluation of Cytologically indeterminate thyroid nodules. Zhou L, Jiang J, Fu Y, Zhang D, Li T, Fu Q, Yan C, Zhong Y, Dionigi G, Liang N, Sun H., Free PMC Article | 02/12/2022 |
Midkine-A potential therapeutic target in melanoma. | Midkine-A potential therapeutic target in melanoma. Donia M, Jönsson G. | 02/5/2022 |
Shedding more light on the role of Midkine in hepatocellular carcinoma: New perspectives on diagnosis and therapy. | Shedding more light on the role of Midkine in hepatocellular carcinoma: New perspectives on diagnosis and therapy. Gowhari Shabgah A, Ezzatifar F, Aravindhan S, Olegovna Zekiy A, Ahmadi M, Gheibihayat SM, Gholizadeh Navashenaq J. | 01/29/2022 |
Midkine: Utility as a Predictor of Early Diabetic Nephropathy in Children with Type 1 Diabetes Mellitus | Midkine: Utility as a Predictor of Early Diabetic Nephropathy in Children with Type 1 Diabetes Mellitus. Metwalley KA, Farghaly HS, Gabri MF, Abdel-Aziz SM, Ismail AM, Raafat DM, Elnakeeb IF., Free PMC Article | 01/22/2022 |
Serum midkine level might be a diagnostic tool for COVID19 disease in pregnancy: From the disease severity, hospitalization and disease progression respects. | Serum midkine level might be a diagnostic tool for COVID19 disease in pregnancy: From the disease severity, hospitalization and disease progression respects. Yazihan N, Erol SA, Akdas S, Goncu Ayhan S, Atalay A, Yildirim M, Biriken D, Akin I, Altiner S, Ceylan MN, Tanacan A, Keskin HL, Moraloglu Tekin O, Sahin D., Free PMC Article | 12/11/2021 |
Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells. | Midkine signaling maintains the self-renewal and tumorigenic capacity of glioma initiating cells. López-Valero I, Dávila D, González-Martínez J, Salvador-Tormo N, Lorente M, Saiz-Ladera C, Torres S, Gabicagogeascoa E, Hernández-Tiedra S, García-Taboada E, Mendiburu-Eliçabe M, Rodríguez-Fornés F, Sánchez-Domínguez R, Segovia JC, Sánchez-Gómez P, Matheu A, Sepúlveda JM, Velasco G., Free PMC Article | 05/15/2021 |
Association of Midkine and Pleiotrophin Gene Polymorphisms With Systemic Lupus Erythematosus Susceptibility in Chinese Han Population. | Association of Midkine and Pleiotrophin Gene Polymorphisms With Systemic Lupus Erythematosus Susceptibility in Chinese Han Population. Wang P, Mao YM, Zhao CN, Wang JB, Li XM, Ye DQ, Pan HF., Free PMC Article | 05/15/2021 |
Serum Midkine is a clinical significant biomarker for colorectal cancer and associated with poor survival. | Serum Midkine is a clinical significant biomarker for colorectal cancer and associated with poor survival. Kemper M, Hentschel W, Graß JK, Stüben BO, Konczalla L, Rawnaq T, Ghadban T, Izbicki JR, Reeh M., Free PMC Article | 04/24/2021 |
Serum Midkine, estimated glomerular filtration rate and chronic kidney disease-related events in elderly women: Perth Longitudinal Study of Aging Women. | Serum Midkine, estimated glomerular filtration rate and chronic kidney disease-related events in elderly women: Perth Longitudinal Study of Aging Women. Wang J, Lewis JR, Byrnes E, Wong G, Raymond WD, Zhu K, Robertson GR, Lim WH, Cao Q, Prince RL, Lee VW., Free PMC Article | 03/6/2021 |
A combination of alpha-fetoprotein, midkine, thioredoxin and a metabolite for predicting hepatocellular carcinoma. | A combination of α-fetoprotein, midkine, thioredoxin and a metabolite for predicting hepatocellular carcinoma. Omran MM, Farid K, Omar MA, Emran TM, El-Taweel FM, Tabll AA. | 02/13/2021 |
Midkine promotes articular chondrocyte proliferation through the MK-LRP1-nucleolin signaling pathway. | Midkine promotes articular chondrocyte proliferation through the MK-LRP1-nucleolin signaling pathway. Deng Q, Yu X, Deng S, Ye H, Zhang Y, Han W, Li J, Yu Y. | 02/6/2021 |
Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state. | Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state. Cerezo-Wallis D, Contreras-Alcalde M, Troulé K, Catena X, Mucientes C, Calvo TG, Cañón E, Tejedo C, Pennacchi PC, Hogan S, Kölblinger P, Tejero H, Chen AX, Ibarz N, Graña-Castro O, Martinez L, Muñoz J, Ortiz-Romero P, Rodriguez-Peralto JL, Gómez-López G, Al-Shahrour F, Rabadán R, Levesque MP, Olmeda D, Soengas MS. | 02/2/2021 |