| SNORD115-1 gene is imprinted, with preferential expression from the paternal allele in the brain. | Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization.
Cavaillé J, Buiting K, Kiefmann M, Lalande M, Brannan CI, Horsthemke B, Bachellerie JP, Brosius J, Hüttenhofer A., Free PMC Article | 10/26/2010 |
| The likely evolutionary history of the HBII-52 cluster and SNORD119 and suggest that they have evolved from a common ancestor, is constructed. | Molecular evolution of the HBII-52 snoRNA cluster.
Nahkuri S, Taft RJ, Korbie DJ, Mattick JS. | 01/21/2010 |
| results show that a snoRNA regulates the processing of an mRNA expressed from a gene located on a different chromosome, and the results indicate that a defect in pre-mRNA processing contributes to the Prader-Willi syndrome | The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C.
Kishore S, Stamm S. | 01/21/2010 |
| Since the complete loss of the HBII-52 genes in family members who carry the deletion on their paternal chromosome is not associated with an obvious clinical phenotype, we conclude that HBII-52 snoRNA genes do not play a major role in PWS. | Exclusion of the C/D box snoRNA gene cluster HBII-52 from a major role in Prader-Willi syndrome.
Runte M, Varon R, Horn D, Horsthemke B, Buiting K. | 01/21/2010 |