| A poly-histidine motif of HOXA1 is involved in regulatory interactions with cysteine-rich proteins. | A poly-histidine motif of HOXA1 is involved in regulatory interactions with cysteine-rich proteins.
Marchese D, Guislain F, Pringels T, Bridoux L, Rezsohazy R. | 02/16/2024 |
| Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction. | Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction.
Chen Q, Chen Q, Song Y, Xiang Y, Li Q, Sang Y, Zhang L, Bai L, Zhu Y. | 01/3/2024 |
| Circ_0058063 regulates the development of esophageal cancer through miR-377-3p/HOXA1 axis. | Circ_0058063 regulates the development of esophageal cancer through miR-377-3p/HOXA1 axis.
Chen L, Luo C, Xu Y, Hu J, Chen H. | 03/14/2023 |
| HOXA1 promotes proliferation and metastasis of bladder cancer by enhancing SMAD3 transcription. | HOXA1 promotes proliferation and metastasis of bladder cancer by enhancing SMAD3 transcription.
Chen S, Shu G, Wang G, Ye J, Xu J, Huang C, Yang S. | 12/3/2022 |
| HOXA1, a breast cancer oncogene. | HOXA1, a breast cancer oncogene.
Belpaire M, Taminiau A, Geerts D, Rezsohazy R. | 08/13/2022 |
| Hsa_circ_0074032 promotes prostate cancer progression through elevating homeobox A1 expression by serving as a microRNA-198 decoy. | Hsa_circ_0074032 promotes prostate cancer progression through elevating homeobox A1 expression by serving as a microRNA-198 decoy.
Feng C, Wang Q, Deng L, Peng N, Yang M, Wang X. | 01/15/2022 |
| CircRASSF2 acts as a prognostic factor and promotes breast cancer progression by modulating miR-1205/HOXA1 axis. | CircRASSF2 acts as a prognostic factor and promotes breast cancer progression by modulating miR-1205/HOXA1 axis.
Zhong W, Bao L, Yuan Y, Meng Y., Free PMC Article | 12/4/2021 |
| MiR-10a-5p restrains the aggressive phenotypes of ovarian cancer cells by inhibiting HOXA1. | MiR-10a-5p restrains the aggressive phenotypes of ovarian cancer cells by inhibiting HOXA1.
Liu LJ, Sun XY, Yang CX, Zou XY. | 12/4/2021 |
| LncRNA HOTAIRM1 promotes MDSC expansion and suppressive functions through the HOXA1-miR124 axis during HCV infection. | LncRNA HOTAIRM1 promotes MDSC expansion and suppressive functions through the HOXA1-miR124 axis during HCV infection.
Thakuri BKC, Zhang J, Zhao J, Nguyen LN, Nguyen LNT, Khanal S, Cao D, Dang X, Schank M, Wu XY, Morrison ZD, Gazzar ME, Li Z, Jiang Y, Ning S, Wang L, Moorman JP, Yao ZQ., Free PMC Article | 09/11/2021 |
| miR-18a-3p Encourages Apoptosis of Chondrocyte in Osteoarthritis via HOXA1 Pathway. | miR-18a-3p Encourages Apoptosis of Chondrocyte in Osteoarthritis via HOXA1 Pathway.
Ding B, Xu S, Sun X, Gao J, Nie W, Xu H. | 08/14/2021 |
| Long non-coding RNA SNHG1 activates HOXA1 expression via sponging miR-193a-5p in breast cancer progression. | Long non-coding RNA SNHG1 activates HOXA1 expression via sponging miR-193a-5p in breast cancer progression.
Li J, Zeng T, Li W, Wu H, Sun C, Yang F, Yang M, Fu Z, Yin Y., Free PMC Article | 03/13/2021 |
| Long noncoding RNA HOTAIRM1 promotes myeloid-derived suppressor cell expansion and suppressive functions through up-regulating HOXA1 expression during latent HIV infection. | Long noncoding RNA HOTAIRM1 promotes myeloid-derived suppressor cell expansion and suppressive functions through up-regulating HOXA1 expression during latent HIV infection.
Zhang J, Thakuri BKC, Zhao J, Nguyen LN, Nguyen LNT, Cao D, Dang X, Khanal S, Schank M, Lu Z, Wu XY, Morrison ZD, Gazzar ME, Li Z, Jiang Y, Ning S, Wang L, Moorman JP, Yao ZQ., Free PMC Article | 02/20/2021 |
| MiR-99a suppressed cell proliferation and invasion by directly targeting HOXA1 through regulation of the AKT/mTOR signaling pathway and EMT in ovarian cancer. | MiR-99a suppressed cell proliferation and invasion by directly targeting HOXA1 through regulation of the AKT/mTOR signaling pathway and EMT in ovarian cancer.
Zhang L, Liu XL, Yuan Z, Cui J, Zhang H. | 09/19/2020 |
| Long non-coding RNA 00152 promotes cell proliferation in cervical cancer via regulating miR-216b-5p/HOXA1 axis. | Long non-coding RNA 00152 promotes cell proliferation in cervical cancer via regulating miR-216b-5p/HOXA1 axis.
Zheng JJ, Du XJ, Wang HP, Zhou LY, Wang YJ, Zhang L, Xu H, Zhang J, Hu ZF. | 09/19/2020 |
| demonstrate for first time that miR-99a-5p may serve as a potential inhibitor of the atherosclerosis, and miR-99a-5p plays its role partially through targeting HOXA1 | MicroRNA-99a-5p alleviates atherosclerosis via regulating Homeobox A1.
Han Z, Guan Y, Liu B, Lin Y, Yan Y, Wang H, Wang H, Jing B. | 10/12/2019 |
| this study illustrates that HOTAIRM1/HOXA1 downregulates the immunosuppressive function of myeloid-derived suppressor celsl and may be a potential therapeutic target in lung cancer. | Long Non-Coding RNA HOXA Transcript Antisense RNA Myeloid-Specific 1-HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer.
Tian X, Ma J, Wang T, Tian J, Zhang Y, Mao L, Xu H, Wang S., Free PMC Article | 06/29/2019 |
| these results indicated that miR577 may have served tumor suppressive roles in nonsmall cell lung cancer by directly targeting HOXA1. | microRNA‑577 inhibits cell proliferation and invasion in non‑small cell lung cancer by directly targeting homeobox A1.
Men L, Nie D, Nie H. | 06/1/2019 |
| The O-GlcNAc transferase OGT interacts with and post-translationally modifies the transcription factor HOXA1. | The O-GlcNAc transferase OGT interacts with and post-translationally modifies the transcription factor HOXA1.
Draime A, Bridoux L, Belpaire M, Pringels T, Degand H, Morsomme P, Rezsohazy R. | 02/9/2019 |
| Results find that HOXA1 expression is regulated in glioblastoma multiforme by HOTAIRM1 which decreases DNA methylation levels in the HOXA1 promoter region by reducing DNA methyltransferases. | Over-expressed lncRNA HOTAIRM1 promotes tumor growth and invasion through up-regulating HOXA1 and sequestering G9a/EZH2/Dnmts away from the HOXA1 gene in glioblastoma multiforme.
Li Q, Dong C, Cui J, Wang Y, Hong X., Free PMC Article | 01/12/2019 |
| We speculate that HOXA1 may be the direct target of miR181b5p or miR181d5p in LUSC, and HOXA1 may serve a significant role in nonsmall cell lung cancer (NSCLC) by regulating various pathways, particularly the p53 signaling pathway. | Upregulation of HOXA1 promotes tumorigenesis and development of non‑small cell lung cancer: A comprehensive investigation based on reverse transcription-quantitative polymerase chain reaction and bioinformatics analysis.
Zhang Y, Li XJ, He RQ, Wang X, Zhang TT, Qin Y, Zhang R, Deng Y, Wang HL, Luo DZ, Chen G., Free PMC Article | 10/6/2018 |
| Study revealed the existence of negative correlation between the expression of miR577 and HOXA1 in hepatocellular carcinoma (HCC) specimens. HOXA1 expression is under the direct regulation of miR577 which is able to bind to its 3'UTR. | MicroRNA‑577 inhibits the migration and invasion of hepatocellular carcinoma cells by targeting homeobox A1.
Han S, Liu Z, Wang Y, Wang L, Yao B, Guo C, Song T, Tu K, Liu Q. | 09/29/2018 |
| HOTTIP cooperates with CTCF to coordinate HOXA gene expression. | Long noncoding RNA HOTTIP cooperates with CCCTC-binding factor to coordinate HOXA gene expression.
Wang F, Tang Z, Shao H, Guo J, Tan T, Dong Y, Lin L. | 09/8/2018 |
| that miR-433 was frequently downregulated in colon cancer tissues and cell lines. Overexpression of miR-433 significantly inhibited the proliferation and invasion of colon cancer. We also newly identified HOXA1 as a direct target of miR-433. The effects of miR-433 on colon cancer cells were mediated via HOXA1. | MicroRNA-433 Represses Proliferation and Invasion of Colon Cancer Cells by Targeting Homeobox A1.
Li H, Li J, Yang T, Lin S, Li H., Free PMC Article | 09/1/2018 |
| we found that KDM3B exhibits potential tumor-suppressive activity and transcriptionally modulates HOXA1 expression via RARE in AML. | KDM3B shows tumor-suppressive activity and transcriptionally regulates HOXA1 through retinoic acid response elements in acute myeloid leukemia.
Xu X, Nagel S, Quentmeier H, Wang Z, Pommerenke C, Dirks WG, Macleod RAF, Drexler HG, Hu Z. | 08/4/2018 |
| miR-30c could suppress giant cell tumor of bone cell proliferation and progression via HOXA1, which might provide a new target for giant cell tumor of bone diagnosis and therapy | MicroRNA-30c suppressed giant-cell tumor of bone cell metastasis and growth via targeting HOXA1.
Ni LY, Zhao JD, Lu YH, Li W, Li BL, Wang XC, Meng QG. | 07/28/2018 |