| Identification of a novel GOLGA4-JAK2 fusion gene in B-cell acute lymphoblastic leukaemia. | Identification of a novel GOLGA4-JAK2 fusion gene in B-cell acute lymphoblastic leukaemia.
Downes CEJ, Rehn J, Heatley SL, Yeung D, McClure BJ, White DL. | 02/19/2022 |
| CrpF46 regulates cell migration by centrosomal reorientation and altering the function of the actomyosin network by controlling specific phosphorylation of myosin. | The actomyosin network is influenced by NMHC IIA and regulated by Crp(F46), which is involved in controlling cell migration.
Cao Y, Lei Y, Luo Y, Tan T, Du B, Zheng Y, Sun L, Liang Q. | 09/28/2019 |
| This study provides Class III evidence that elevated cerebrospinal fluid golgin A4 levels identify patients with Alzheimer disease. | Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease.
Kork F, Jankowski J, Goswami A, Weis J, Brook G, Yamoah A, Anink J, Aronica E, Fritz S, Huck C, Schipke C, Peters O, Tepel M, Noels H, Jankowski V. | 09/7/2019 |
| p230 is an important molecule in phagophore formation, although it remains unclear whether p230 has any role in late steps of autophagy | Trans-Golgi protein p230/golgin-245 is involved in phagophore formation.
Sohda M, Misumi Y, Ogata S, Sakisaka S, Hirose S, Ikehara Y, Oda K. | 03/21/2015 |
| CD99 also binds p230/golgin-245, a coiled-coil protein that recycles between the cytosol and buds/vesicles of the TGN and which plays a fundamental role in trafficking transport vesicles. | Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction.
Brémond A, Meynet O, Mahiddine K, Coito S, Tichet M, Scotlandi K, Breittmayer JP, Gounon P, Gleeson PA, Bernard A, Bernard G. | 01/21/2010 |
| The protein CrpF46 has an apparent molecular mass of ~60 kDa, is highly homologous to a 527 amino acid sequence of the C-terminal portion of the protein Golgin-245, and appears to be a splice variant of Golgin-245. | Identification of a novel centrosomal protein CrpF46 involved in cell cycle progression and mitosis.
Wei Y, Shen E, Zhao N, Liu Q, Fan J, Marc J, Wang Y, Sun L, Liang Q. | 01/21/2010 |
| golgin-245 is a key regulator of TNF secretion; LPS activation of macrophages results in increased Golgi carriers for export, up-regulating the transport pathway for TNF export. | A trans-Golgi network golgin is required for the regulated secretion of TNF in activated macrophages in vivo.
Lieu ZZ, Lock JG, Hammond LA, La Gruta NL, Stow JL, Gleeson PA., Free PMC Article | 01/21/2010 |
| The ability of the four mammalian GRIP domain proteins, p230, golgin-97, GCC88, and GCC185 to interact is reported. | The trans-Golgi network GRIP-domain proteins form alpha-helical homodimers.
Luke MR, Houghton F, Perugini MA, Gleeson PA., Free PMC Article | 01/21/2010 |
| tGolgin-1 functions in Golgi positioning indirectly, probably by regulating retrograde movement of cargo required for recruitment or activation of dynein-dynactin complexes on newly formed Golgi elements. | tGolgin-1 (p230, golgin-245) modulates Shiga-toxin transport to the Golgi and Golgi motility towards the microtubule-organizing centre.
Yoshino A, Setty SR, Poynton C, Whiteman EL, Saint-Pol A, Burd CG, Johannes L, Holzbaur EL, Koval M, McCaffery JM, Marks MS. | 01/21/2010 |
| crystal structure of Arl1-GTP in complex with the GRIP domain of golgin-245 shows that Arl1-GTP interacts with the GRIP domain predominantly in a hydrophobic manner, with the switch II region conferring the main recognition surface | Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1.
Wu M, Lu L, Hong W, Song H. | 01/21/2010 |
| P230, through its interaction with MACF1, provides the molecular link for transport of GPI-anchored proteins along the microtubule and actin cytoskeleton from the TGN to the cell periphery. | Interaction between p230 and MACF1 is associated with transport of a glycosyl phosphatidyl inositol-anchored protein from the Golgi to the cell periphery.
Kakinuma T, Ichikawa H, Tsukada Y, Nakamura T, Toh BH. | 01/21/2010 |