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    GMFB glia maturation factor beta [ Homo sapiens (human) ]

    Gene ID: 2764, updated on 11-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Parkinson's Disease Dementia Patients: Expression of Glia Maturation Factor in the Brain.

    Parkinson's Disease Dementia Patients: Expression of Glia Maturation Factor in the Brain.
    Thangavel R, Kaur H, Dubova I, Selvakumar GP, Ahmed ME, Raikwar SP, Govindarajan R, Kempuraj D.

    02/28/2024
    G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease.

    G9a Inhibition Promotes Neuroprotection through GMFB Regulation in Alzheimer's Disease.
    Bellver-Sanchis A, Geng Q, Navarro G, Ávila-López PA, Companys-Alemany J, Marsal-García L, Larramona-Arcas R, Miró L, Perez-Bosque A, Ortuño-Sahagún D, Banerjee DR, Choudhary BS, Soriano FX, Poulard C, Pallàs M, Du HN, Griñán-Ferré C., Free PMC Article

    01/26/2024
    MicroRNA-5195-3p alleviates high glucoseinduced injury in human ARPE-19 cells by targeting GMFB.

    MicroRNA-5195-3p alleviates high glucose‑induced injury in human ARPE-19 cells by targeting GMFB.
    Liu J, Hou Y, Lin L, Yu N, Zhang Y., Free PMC Article

    01/22/2022
    GMF acts as an important upstream regulator of PGC-1alpha in promoting dopaminergic neuronal death through its effect on oxidative stress-mediated apoptosis.

    Glia Maturation Factor Dependent Inhibition of Mitochondrial PGC-1α Triggers Oxidative Stress-Mediated Apoptosis in N27 Rat Dopaminergic Neuronal Cells.
    Selvakumar GP, Iyer SS, Kempuraj D, Raju M, Thangavel R, Saeed D, Ahmed ME, Zahoor H, Raikwar SP, Zaheer S, Zaheer A., Free PMC Article

    02/9/2019
    GMF and ApoE4 were strongly expressed and co-associated in amyloid plaques (APs) and in the reactive astrocytes surrounding APs in Alzheimer's disease.

    Co-Expression of Glia Maturation Factor and Apolipoprotein E4 in Alzheimer's Disease Brain.
    Thangavel R, Bhagavan SM, Ramaswamy SB, Surpur S, Govindarajan R, Kempuraj D, Zaheer S, Raikwar S, Ahmed ME, Selvakumar GP, Iyer SS, Zaheer A., Free PMC Article

    01/19/2019
    GMF-beta is an important player in glioma progression via promoting neovascularization.

    Expressions of glia maturation factor-β by tumor cells and endothelia correlate with neovascularization and poor prognosis in human glioma.
    Kuang XY, Jiang XF, Chen C, Su XR, Shi Y, Wu JR, Zhang P, Zhang XL, Cui YH, Ping YF, Bian XW., Free PMC Article

    02/24/2018
    The distribution of GMF-immunoreactive cells in and around amyloid plaques and neurofibrillary tangles suggests involvement of GMF in inflammatory responses through reactive glia and a role of GMF in Alzheimer disease pathology.

    Expression of glia maturation factor in neuropathological lesions of Alzheimer's disease.
    Thangavel R, Stolmeier D, Yang X, Anantharam P, Zaheer A., Free PMC Article

    02/23/2013
    GMF co-localizes with amyloid plaques and neurofibrillary tangles in Alzheimer brains, implicating significant upregulation of GMF expression under conditions of neurodegeneration.

    Augmented expression of glia maturation factor in Alzheimer's disease.
    Zaheer S, Thangavel R, Sahu SK, Zaheer A., Free PMC Article

    06/30/2012
    There is a significant increase in GMF beta protein expression levels in IFN beta-1a treated LX-2 cells.

    [Effect of glia maturation factor beta on the activation of hepatic stellate cells and on liver fibrosis].
    Rao HY, Wang JH, Liu F, Fei R, Liu ZD, Wei L.

    07/12/2010
    Observational study of gene-disease association. (HuGE Navigator)

    Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
    Gratacòs M, Costas J, de Cid R, Bayés M, González JR, Baca-García E, de Diego Y, Fernández-Aranda F, Fernández-Piqueras J, Guitart M, Martín-Santos R, Martorell L, Menchón JM, Roca M, Sáiz-Ruiz J, Sanjuán J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A, Psychiatric Genetics Network Group.

    01/11/2009
    GMFB promoted T-cell differentiation into CD4-/CD8+ cells when analysed by two-colour flow cytometry.

    Glia maturation factor-beta is produced by thymoma and may promote intratumoral T-cell differentiation.
    Yamazaki H, Tateyama H, Asai K, Fukai I, Fujii Y, Tada T, Eimoto T.

    01/21/2010
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