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    IL37 interleukin 37 [ Homo sapiens (human) ]

    Gene ID: 27178, updated on 7-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    IL-37 dampens immunosuppressive functions of MDSCs via metabolic reprogramming in the tumor microenvironment.

    IL-37 dampens immunosuppressive functions of MDSCs via metabolic reprogramming in the tumor microenvironment.
    Mei Y, Zhu Y, Yong KSM, Hanafi ZB, Gong H, Liu Y, Teo HY, Hussain M, Song Y, Chen Q, Liu H.

    04/1/2024
    Interleukin-37 relieves PM2.5-triggered lung injury by inhibiting autophagy through the AKT/mTOR signaling pathway in vivo and in vitro.

    Interleukin-37 relieves PM2.5-triggered lung injury by inhibiting autophagy through the AKT/mTOR signaling pathway in vivo and in vitro.
    Cao J, Hou S, Chen Z, Yan J, Chao L, Qian Y, Li J, Yan X.

    02/1/2024
    Potential Role of IL-37 in Atopic Dermatitis.

    Potential Role of IL-37 in Atopic Dermatitis.
    Mesjasz A, Trzeciak M, Gleń J, Jaskulak M., Free PMC Article

    01/12/2024
    [Expression of interleukin-37, vascular endothelial growth factor A, and transforming growth factor-beta1 and their correlation with T cells in children with primary immune thrombocytopenia].

    [Expression of interleukin-37, vascular endothelial growth factor A, and transforming growth factor-β1 and their correlation with T cells in children with primary immune thrombocytopenia].
    Tong LL, Wang LH, Fang F, Xu B, Zheng SH., Free PMC Article

    12/1/2023
    Novel insights into IL-37: an anti-inflammatory cytokine with emerging roles in anti-cancer process.

    Novel insights into IL-37: an anti-inflammatory cytokine with emerging roles in anti-cancer process.
    Gu M, Jin Y, Gao X, Xia W, Xu T, Pan S., Free PMC Article

    11/21/2023
    Correlation analysis of IL-37 gene polymorphisms and susceptibility to chronic HBV infection among Han people in Central China.

    Correlation analysis of IL-37 gene polymorphisms and susceptibility to chronic HBV infection among Han people in Central China.
    Cheng H, Sun F, Ouyang Y, Li C.

    11/13/2023
    Modulation of intestinal IL-37 expression and its impact on the epithelial innate immune response and barrier integrity.

    Modulation of intestinal IL-37 expression and its impact on the epithelial innate immune response and barrier integrity.
    Kröhn L, Azabdaftari A, Heuberger J, Hudert C, Zilbauer M, Breiderhoff T, Bufler P., Free PMC Article

    10/30/2023
    Interleukin-37: associations of plasma levels and genetic variants in gout.

    Interleukin-37: associations of plasma levels and genetic variants in gout.
    Andres Cerezo L, Navrátilová A, Hulejová H, Pavlíková M, Závada J, Pavelka K, Šenolt L, Stiburkova B., Free PMC Article

    10/30/2023
    Upregulation of IL-37 in epithelial cells: A potential new mechanism of T cell inhibition induced by tacrolimus.

    Upregulation of IL-37 in epithelial cells: A potential new mechanism of T cell inhibition induced by tacrolimus.
    Su Z, Lu J, Ling Z, Li W, Yang X, Cheng B, Tao X.

    10/2/2023
    Interleukin-37 inhibits desmoglein-3 endocytosis and keratinocyte dissociation via upregulation of Caveolin-1 and inhibition of the STAT3 pathway.

    Interleukin-37 inhibits desmoglein-3 endocytosis and keratinocyte dissociation via upregulation of Caveolin-1 and inhibition of the STAT3 pathway.
    Liang J, Hu F, Mao L, Qiu Y, Jiang F, Wang Q, Abulikemu K, Hong Y, Ge X, Kang X.

    09/6/2023
    Interleukin-37 suppresses the cytotoxicity of hepatitis B virus peptides-induced CD8+ T cells in patients with acute hepatitis B.

    Interleukin-37 suppresses the cytotoxicity of hepatitis B virus peptides-induced CD8+ T cells in patients with acute hepatitis B.
    Liu Q, Zhou Q, Wang M, Pang B., Free PMC Article

    08/30/2023
    Interleukin -37 in rheumatoid arthritis: Correlation with clinical severity and genetic polymorphisms in Mosul city, Iraq.

    Interleukin -37 in rheumatoid arthritis: Correlation with clinical severity and genetic polymorphisms in Mosul city, Iraq.
    Al-Tae FMD, Al-Harbi AA, Turki KW, Sood M.

    08/10/2023
    Estimation of Interleukin 32 and Interleukin 37 Serum Levels in Iraqi Patients with Rheumatoid Arthritis.

    Estimation of Interleukin 32 and Interleukin 37 Serum Levels in Iraqi Patients with Rheumatoid Arthritis.
    Mohammed Jasim E, Khudhur Jameel S, Ihsan Awadh N., Free PMC Article

    07/6/2023
    IL-12 and IL-23 pathway inhibition in inflammatory bowel disease.

    IL-12 and IL-23 pathway inhibition in inflammatory bowel disease.
    Verstockt B, Salas A, Sands BE, Abraham C, Leibovitzh H, Neurath MF, Vande Casteele N, Alimentiv Translational Research Consortium (ATRC).,

    06/29/2023
    Interleukin-23 mediates the reduction of GADD45a expression to attenuate oxidative stress-induced cellular senescence in human fibroblasts.

    Interleukin-23 mediates the reduction of GADD45a expression to attenuate oxidative stress-induced cellular senescence in human fibroblasts.
    Haonan L, Zehang S, Jiacong H, Zhenxing W, Shengli Z, Bailing C, Zhuning C, Haoran K.

    06/9/2023
    Relative CTLA-4, PTPN-22, and interleukin 37 mRNA expressions in patients with lupus nephritis.

    Relative CTLA-4, PTPN-22, and interleukin 37 mRNA expressions in patients with lupus nephritis.
    A Moneim NH, Hosny MM, Omar HH, Abdelnaby MM, Fouad MM, Abd El-Waheed WO, Elmedany SH, Zaki HM.

    04/19/2023
    Polymorphism Analysis of Interleukin-18 and Interleukin-37 Genes in Hepatitis B Infections with Different Outcomes: A Preliminary Report from an Iranian Population.

    Polymorphism Analysis of Interleukin-18 and Interleukin-37 Genes in Hepatitis B Infections with Different Outcomes: A Preliminary Report from an Iranian Population.
    Molaei V, Fattahi MR, Haghshenas MR, Hosseini SY, Malekhosseini SA, Sarvari J., Free PMC Article

    03/8/2023
    A Critical Appraisal of the Diagnostic and Prognostic Utility of the Anti-Inflammatory Marker IL-37 in a Clinical Setting: A Case Study of Patients with Diabetes Type 2.

    A Critical Appraisal of the Diagnostic and Prognostic Utility of the Anti-Inflammatory Marker IL-37 in a Clinical Setting: A Case Study of Patients with Diabetes Type 2.
    Bosnić Z, Babič F, Anderková V, Štefanić M, Wittlinger T, Majnarić LT., Free PMC Article

    02/28/2023
    Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs.

    Circulating interleukin-37 declines with aging in healthy humans: relations to healthspan indicators and IL37 gene SNPs.
    Brunt VE, Ikoba AP, Ziemba BP, Ballak DB, Hoischen A, Dinarello CA, Ehringer MA, Seals DR., Free PMC Article

    02/4/2023
    Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study.

    Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study.
    Teufel LU, van der Made CI, Klück V, Simons A, Hoischen A, Vernimmen V, Joosten LAB, Arts RJW.

    01/28/2023
    Evaluation of interleukins 37 and 38 and vitamin D status in the serum of women with Graves' disease.

    Evaluation of interleukins 37 and 38 and vitamin D status in the serum of women with Graves' disease.
    Ibrahim HY, Sulaiman GM, Al-Shammaa MS, Ad'hiah AH., Free PMC Article

    01/14/2023
    Myeloid cell-derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement.

    Myeloid cell-derived proteases produce a proinflammatory form of IL-37 that signals via IL-36 receptor engagement.
    Sullivan GP, Davidovich P, Muñoz-Wolf N, Ward RW, Hernandez Santana YE, Clancy DM, Gorman A, Najda Z, Turk B, Walsh PT, Lavelle EC, Martin SJ.

    12/24/2022
    Imbalanced IL-37/TNF-alpha/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro.

    Imbalanced IL-37/TNF-α/CTSS signaling disrupts corneal epithelial barrier in a dry eye model in vitro.
    Zhang Y, Li JM, Lu R, Liu Z, Chen X, de Paiva CS, Pflugfelder SC, Li DQ., Free PMC Article

    12/17/2022
    Serum levels of IL-37 and correlation with inflammatory cytokines and clinical outcomes in patients with coronary artery disease.

    Serum levels of IL-37 and correlation with inflammatory cytokines and clinical outcomes in patients with coronary artery disease.
    Rafiei A, Ahmadi R, Kazemian S, Rahimzadeh-Fallah T, Mohammad-Rezaei M, Azadegan-Dehkordi F, Sanami S, Mirzaei Y, Aghaei F, Bagheri N., Free PMC Article

    12/10/2022
    Mast Cell Cytokines in Acute and Chronic Gingival Tissue Inflammation: Role of IL-33 and IL-37.

    Mast Cell Cytokines in Acute and Chronic Gingival Tissue Inflammation: Role of IL-33 and IL-37.
    Trimarchi M, Lauritano D, Ronconi G, Caraffa A, Gallenga CE, Frydas I, Kritas SK, Calvisi V, Conti P., Free PMC Article

    11/26/2022
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