| FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1. | FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1.
Sun X, Gao C, Xu X, Li M, Zhao X, Wang Y, Wang Y, Zhang S, Yan Z, Liu X, Wu C., | 09/8/2023 |
| Current research on viral proteins that interact with fibrillarin. | Current research on viral proteins that interact with fibrillarin.
Decle-Carrasco S, Rodríguez-Piña AL, Rodríguez-Zapata LC, Castano E., Free PMC Article | 05/8/2023 |
| A PRC2-independent function for EZH2 in regulating rRNA 2'-O methylation and IRES-dependent translation. | A PRC2-independent function for EZH2 in regulating rRNA 2'-O methylation and IRES-dependent translation.
Yi Y, Li Y, Meng Q, Li Q, Li F, Lu B, Shen J, Fazli L, Zhao D, Li C, Jiang W, Wang R, Liu Q, Szczepanski A, Li Q, Qin W, Weiner AB, Lotan TL, Ji Z, Kalantry S, Wang L, Schaeffer EM, Niu H, Dong X, Zhao W, Chen K, Cao Q., Free PMC Article | 06/26/2021 |
| Phase transition of fibrillarin LC domain regulates localization and protein interaction of fibrillarin. | Phase transition of fibrillarin LC domain regulates localization and protein interaction of fibrillarin.
Kim E, Kwon I. | 06/19/2021 |
| Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids. | Fibrillarin Ribonuclease Activity is Dependent on the GAR Domain and Modulated by Phospholipids.
Guillen-Chable F, Corona UR, Pereira-Santana A, Bayona A, Rodríguez-Zapata LC, Aquino C, Šebestová L, Vitale N, Hozak P, Castano E., Free PMC Article | 02/27/2021 |
| This is the first report on the clinical aspect of ribosome biogenesis in pediatric BCP-ALL [B-cell precursor acute lymphoblastic leukemia ], and it shows that overexpression of CMYC and C/D box nucleoproteins FBL and NOP56 is an antecedent event in patients who subsequently relapse. | Analysis of the rRNA methylation complex components in pediatric B-cell precursor acute lymphoblastic leukemia: A pilot study.
Ussowicz M, Marcel V, Long FNV, Kazanowska B, Diaz JJ, Wołowiec D. | 03/7/2020 |
| SIRT7-dependent deacetylation impacts nucleolar activity by an FBL-driven circuitry that mediates cell-cycle-dependent fluctuation of ribosomal DNA transcription. | SIRT7-Dependent Deacetylation of Fibrillarin Controls Histone H2A Methylation and rRNA Synthesis during the Cell Cycle.
Iyer-Bierhoff A, Krogh N, Tessarz P, Ruppert T, Nielsen H, Grummt I. | 12/7/2019 |
| Fibrillarin acts as a central node in a regulatory network engaged in imparting immunity against bacterial pathogens. | Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance.
Tiku V, Kew C, Mehrotra P, Ganesan R, Robinson N, Antebi A., Free PMC Article | 12/29/2018 |
| Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions. | Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions.
Shubina MY, Musinova YR, Sheval EV. | 01/14/2017 |
| FBL overexpression contributes to tumorigenesis and is associated with poor survival in patients with breast cancer. | p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer.
Marcel V, Ghayad SE, Belin S, Therizols G, Morel AP, Solano-Gonzàlez E, Vendrell JA, Hacot S, Mertani HC, Albaret MA, Bourdon JC, Jordan L, Thompson A, Tafer Y, Cong R, Bouvet P, Saurin JC, Catez F, Prats AC, Puisieux A, Diaz JJ., Free PMC Article | 12/14/2013 |
| NS1 protein of the human H3N2 virus interacts primarily via the C-terminal NLS2/NoLS and to a minor extent via the N-terminal NLS1 with the main nucleolar proteins, nucleolin, B23 and fibrillarin. | Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin.
Melén K, Tynell J, Fagerlund R, Roussel P, Hernandez-Verdun D, Julkunen I., Free PMC Article | 04/20/2013 |
| p32 is a new rRNA maturation factor involved in the remodeling from pre-90S particles to pre-40S and pre-60S particles that requires the exchange of FBL for Nop52. | Splicing factor 2-associated protein p32 participates in ribosome biogenesis by regulating the binding of Nop52 and fibrillarin to preribosome particles.
Yoshikawa H, Komatsu W, Hayano T, Miura Y, Homma K, Izumikawa K, Ishikawa H, Miyazawa N, Tachikawa H, Yamauchi Y, Isobe T, Takahashi N., Free PMC Article | 06/2/2012 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium., Free PMC Article | 09/15/2010 |
| Data demonstrate that fibrillarin and Nop56 directly interact in vivo, and that this interaction is indispensable for the association of both proteins with the box C/D snoRNPs. | Fibrillarin and Nop56 interact before being co-assembled in box C/D snoRNPs.
Lechertier T, Grob A, Hernandez-Verdun D, Roussel P. | 01/21/2010 |
| Evidence that BIG1 and nucleolin, but not fibrillarin, can be present with p62 at the nuclear envelope confirms the presence of BIG1 and nucleolin in dynamic molecular complexes that change in composition while moving through nuclei | Association of guanine nucleotide-exchange protein BIG1 in HepG2 cell nuclei with nucleolin, U3 snoRNA, and fibrillarin.
Padilla PI, Uhart M, Pacheco-Rodriguez G, Peculis BA, Moss J, Vaughan M., Free PMC Article | 01/21/2010 |
| Increased levels of exogenous BRAG2 in nucleoli result in redistribution of FBL to the nucleolar periphery. | Nuclear functions of the Arf guanine nucleotide exchange factor BRAG2.
Dunphy JL, Ye K, Casanova JE. | 01/21/2010 |
| Our data suggest that fibrillarin would play a critical role in the maintenance of nuclear shape and cellular growth. | Fibrillarin, a nucleolar protein, is required for normal nuclear morphology and cellular growth in HeLa cells.
Amin MA, Matsunaga S, Ma N, Takata H, Yokoyama M, Uchiyama S, Fukui K. | 01/21/2010 |