Eutherian-Specific Gene TRIML2 Attenuates Inflammation in the Evolution of Placentation. | Eutherian-Specific Gene TRIML2 Attenuates Inflammation in the Evolution of Placentation. Zhang X, Pavlicev M, Jones HN, Muglia LJ., Free PMC Article | 10/24/2020 |
the degradation of STAT6 is induced and required for the lytic activation of human herpesviruses and is association with the increased ubiquitylated form of TRIML2 | STAT6 degradation and ubiquitylated TRIML2 are essential for activation of human oncogenic herpesvirus. Gu F, Wang C, Wei F, Wang Y, Zhu Q, Ding L, Xu W, Zhu C, Cai C, Qian Z, Yuan Z, Robertson E, Cai Q., Free PMC Article | 02/16/2019 |
Findings indicate that the C allele of two single nucleotide polymorphisms in the tripartite motif family-like 2 (TRIML2) gene was associated with an increased risk of Alzheimer disease (AD). These results suggest that TRIML2 may contribute to AD susceptibility. | Association of tripartite motif family-like 2 (TRIML2) polymorphisms with late-onset Alzheimer's disease risk in a Korean population. Kang WS, Park JK, Kim YJ, Cho AR, Park HJ, Kim SK, Paik JW, Lee KJ, Na HR, Kim YY, Lim HK, Jeong HG, Kim JW. | 07/29/2017 |
Data indicate that TRIML2 is part of a feed-forward loop that activates p53 in cells expressing the R72 variant, particularly after prolonged stress. | Identification of TRIML2, a novel p53 target, that enhances p53 SUMOylation and regulates the transactivation of proapoptotic genes. Kung CP, Khaku S, Jennis M, Zhou Y, Murphy ME., Free PMC Article | 04/2/2016 |