| Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells. | Induction of Viral Mimicry Upon Loss of DHX9 and ADAR1 in Breast Cancer Cells.
Cottrell KA, Ryu S, Pierce JR, Soto Torres L, Bohlin HE, Schab AM, Weber JD., Free PMC Article | 04/10/2024 |
| Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing. | Malignant A-to-I RNA editing by ADAR1 drives T cell acute lymphoblastic leukemia relapse via attenuating dsRNA sensing.
Rivera M, Zhang H, Pham J, Isquith J, Zhou QJ, Balaian L, Sasik R, Enlund S, Mark A, Ma W, Holm F, Fisch KM, Kuo DJ, Jamieson C, Jiang Q., Free PMC Article | 03/4/2024 |
| Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1. | Impact of Disease-Associated Mutations on the Deaminase Activity of ADAR1.
Karki A, Campbell KB, Mozumder S, Fisher AJ, Beal PA., Free PMC Article | 02/8/2024 |
| ADAR-mediated RNA editing regulates PVR immune checkpoint in colorectal cancer. | ADAR-mediated RNA editing regulates PVR immune checkpoint in colorectal cancer.
Qian CJ, He YS, Guo T, Tao J, Wei ZY, Zhang JL, Bao C, Chen JH. | 02/8/2024 |
| ADAR1 protects pulmonary macrophages from sepsis-induced pyroptosis and lung injury through miR-21/A20 signaling. | ADAR1 protects pulmonary macrophages from sepsis-induced pyroptosis and lung injury through miR-21/A20 signaling.
Zhao X, Xie J, Duan C, Wang L, Si Y, Liu S, Wang Q, Wu D, Wang Y, Yin W, Zhuang R, Li J., Free PMC Article | 01/9/2024 |
| Enhanced mitophagy driven by ADAR1-GLI1 editing supports the self-renewal of cancer stem cells in HCC. | Enhanced mitophagy driven by ADAR1-GLI1 editing supports the self-renewal of cancer stem cells in HCC.
Luo J, Gong L, Yang Y, Zhang Y, Liu Q, Bai L, Fang X, Zhang B, Huang J, Liu M, Liu B, Tang Y, Wong CN, Huang J, Liu S, Li S, Ding T, Man K, Lee VH, Li Y, Ma S, Guan XY. | 12/18/2023 |
| Elevated ADAR expression is significantly linked to shorter overall survival and immune infiltration in patients with lung adenocarcinoma. | Elevated ADAR expression is significantly linked to shorter overall survival and immune infiltration in patients with lung adenocarcinoma.
Hu S, Wang F, Yang J, Xu X. | 12/15/2023 |
| ADAR1 links R-loop homeostasis to ATR activation in replication stress response. | ADAR1 links R-loop homeostasis to ATR activation in replication stress response.
Zhang B, Li Y, Zhang J, Wang Y, Liang C, Lu T, Zhang C, Liu L, Qin Y, He J, Zhao X, Yu J, Hao J, Yang J, Li MJ, Yao Z, Ma S, Cheng H, Cheng T, Shi L., Free PMC Article | 11/30/2023 |
| ADAR1 polymorphisms contribute to increased susceptibility in pediatric acute lymphoblastic leukemia. | ADAR1 polymorphisms contribute to increased susceptibility in pediatric acute lymphoblastic leukemia.
Cai M, Liu X, Luo A, Yang X, Yan Y, Liu S, Wang X, Luo Z, Wu X, Huang K, Yang L, Jiang H, Xu L, Liu X. | 08/23/2023 |
| Clinical significance, tumor immune landscape and immunotherapy responses of ADAR in pan-cancer and its association with proliferation and metastasis of bladder cancer. | Clinical significance, tumor immune landscape and immunotherapy responses of ADAR in pan-cancer and its association with proliferation and metastasis of bladder cancer.
Yu H, Bai K, Cheng Y, Lv J, Song Q, Yang H, Lu Q, Yang X., Free PMC Article | 08/3/2023 |
| RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing. | RNA editing of AZIN1 coding sites is catalyzed by ADAR1 p150 after splicing.
Xing Y, Nakahama T, Wu Y, Inoue M, Kim JI, Todo H, Shibuya T, Kato Y, Kawahara Y., Free PMC Article | 08/3/2023 |
| ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma. | ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.
Yang W, Chen K, Yu Q, Liao R, He H, Peng Y, Yang Z, Zhang X., Free PMC Article | 07/21/2023 |
| RNA Editing Enzyme ADAR1 Suppresses the Mobility of Cancer Cells via ARPIN. | RNA Editing Enzyme ADAR1 Suppresses the Mobility of Cancer Cells via ARPIN.
Park MJ, Jeong E, Lee EJ, Choi HJ, Moon BH, Kang K, Chang S., Free PMC Article | 06/9/2023 |
| Identification of novel interacts partners of ADAR1 enzyme mediating the oncogenic process in aggressive breast cancer. | Identification of novel interacts partners of ADAR1 enzyme mediating the oncogenic process in aggressive breast cancer.
Binothman N, Aljadani M, Alghanem B, Refai MY, Rashid M, Al Tuwaijri A, Alsubhi NH, Alrefaei GI, Khan MY, Sonbul SN, Aljoud F, Alhayyani S, Abdulal RH, Ganash M, Hashem AM., Free PMC Article | 05/31/2023 |
| ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer. | ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer.
Wong TL, Loh JJ, Lu S, Yan HHN, Siu HC, Xi R, Chan D, Kam MJF, Zhou L, Tong M, Copland JA, Chen L, Yun JP, Leung SY, Ma S., Free PMC Article | 05/30/2023 |
| ADAR1 has an oncogenic function and can be a prognostic factor in cervical cancer. | ADAR1 has an oncogenic function and can be a prognostic factor in cervical cancer.
Nakamura K, Shigeyasu K, Okamoto K, Matsuoka H, Masuyama H., Free PMC Article | 03/28/2023 |
| A Comprehensive and Systematic Analysis Revealed the Role of ADAR1 in Pan-Cancer Prognosis and Immune Implications. | A Comprehensive and Systematic Analysis Revealed the Role of ADAR1 in Pan-Cancer Prognosis and Immune Implications.
Zhu J, Zheng J, Zhang J, Wang S, Wang L, Zhao Y., Free PMC Article | 03/7/2023 |
| ADAR1 and ZBP1 in innate immunity, cell death, and disease. | ADAR1 and ZBP1 in innate immunity, cell death, and disease.
Karki R, Kanneganti TD., Free PMC Article | 03/2/2023 |
| ADAR1 is a promising risk stratification biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer. | ADAR1 is a promising risk stratification biomarker of remnant liver recurrence after hepatic metastasectomy for colorectal cancer.
Hata N, Shigeyasu K, Umeda Y, Yano S, Takeda S, Yoshida K, Fuji T, Yoshida R, Yasui K, Umeda H, Takahashi T, Kondo Y, Kishimoto H, Mori Y, Teraishi F, Yamamoto H, Michiue H, Nakamura K, Tazawa H, Fujiwara T., Free PMC Article | 03/1/2023 |
| ADAR1 improved Treg cell function through the miR-21b/Foxp3 axis and inhibits the progression of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. | ADAR1 improved Treg cell function through the miR-21b/Foxp3 axis and inhibits the progression of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Zhao Y, Zheng X, Li M, Zhao J, Wang X, Zhu H. | 02/28/2023 |
| ADAR1-dependent editing regulates human beta cell transcriptome diversity during inflammation. | ADAR1-dependent editing regulates human β cell transcriptome diversity during inflammation.
Szymczak F, Cohen-Fultheim R, Thomaidou S, de Brachène AC, Castela A, Colli M, Marchetti P, Levanon E, Eizirik D, Zaldumbide A., Free PMC Article | 12/24/2022 |
| ADAR activation by inducing a syn conformation at guanosine adjacent to an editing site. | ADAR activation by inducing a syn conformation at guanosine adjacent to an editing site.
Doherty EE, Karki A, Wilcox XE, Mendoza HG, Manjunath A, Matos VJ, Fisher AJ, Beal PA., Free PMC Article | 11/12/2022 |
| Immunosuppressive lncRNA LINC00624 promotes tumor progression and therapy resistance through ADAR1 stabilization. | Immunosuppressive lncRNA LINC00624 promotes tumor progression and therapy resistance through ADAR1 stabilization.
Zhang Q, Xiu B, Zhang L, Chen M, Chi W, Li L, Guo R, Xue J, Yang B, Huang X, Shao ZM, Huang S, Chi Y, Wu J., Free PMC Article | 10/22/2022 |
| RNA Editing Enzyme ADAR1 Regulates METTL3 in an Editing Dependent Manner to Promote Breast Cancer Progression via METTL3/ARHGAP5/YTHDF1 Axis. | RNA Editing Enzyme ADAR1 Regulates METTL3 in an Editing Dependent Manner to Promote Breast Cancer Progression via METTL3/ARHGAP5/YTHDF1 Axis.
Li Y, Wang NX, Yin C, Jiang SS, Li JC, Yang SY., Free PMC Article | 09/24/2022 |
| Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells. | Adenosine-Deaminase-Acting-on-RNA-1 Facilitates T-cell Migration toward Human Melanoma Cells.
Margolis N, Moalem H, Meirson T, Galore-Haskel G, Markovits E, Baruch EN, Vizel B, Yeffet A, Kanterman-Rifman J, Debby A, Besser MJ, Schachter J, Markel G. | 09/17/2022 |