| Genome-wide screening for the G-protein-coupled receptor (GPCR) pathway-related therapeutic gene RGS19 (regulator of G protein signaling 19) in bladder cancer. | Genome-wide screening for the G-protein-coupled receptor (GPCR) pathway-related therapeutic gene RGS19 (regulator of G protein signaling 19) in bladder cancer.
Liu Y, Lou W, Chen G, Ding B, Kuang J, Zhang Y, Wang C, Duan S, Deng Y, Lu X., Free PMC Article | 01/1/2022 |
| RGS19 senses cellular iron availability and is stabilized under iron-depleted conditions, resulting in the induction of a growth-inhibitory signal. | RGS19 converts iron deprivation stress into a growth-inhibitory signal.
Hwang J, Kim HS, Kang BS, Kim DH, Ryoo ZY, Choi SU, Lee S. | 10/3/2015 |
| RGS19 may play an important role in controlling the degree of synergism between FGF-1 receptors and 5-HT1A receptors, that may work together to mediate an anti-depressant effect. | 5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19.
Wang Q, Terauchi A, Yee CH, Umemori H, Traynor JR., Free PMC Article | 03/7/2015 |
| Overall methylation levels in the promoter regions of three genes (ALDH1A1, OPRL1 and RGS19) are elevated in subjects who were exposed to childhood adversity. | Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls.
Zhang H, Wang F, Kranzler HR, Zhao H, Gelernter J., Free PMC Article | 02/1/2014 |
| The RGS19 inhibits Ras signaling through a complex network involving a scaffold protein KSR1 and a nucleoside diphosphate kinase Nm23. | RGS19 inhibits Ras signaling through Nm23H1/2-mediated phosphorylation of the kinase suppressor of Ras.
Tso PH, Wang Y, Yung LY, Tong Y, Lee MM, Wong YH. | 10/19/2013 |
| elevated expression of RGS19 can severely disrupt the regulation of mitogen-activated protein kinases by small GTPases | Elevated expression of RGS19 impairs the responsiveness of stress-activated protein kinases to serum.
Ip AK, Tso PH, Lee MM, Wong YH. | 09/1/2012 |
| cyclin D1/3 and Cdk6 were upregulated in HEK293 cells overexpressing RGS19, while INK4A and INK4B were reduced | RGS19 stimulates cell proliferation by deregulating cell cycle control and enhancing Akt signaling.
Tso PH, Yung LY, Wang Y, Wong YH. | 10/8/2011 |
| Observational study of gene-disease association. (HuGE Navigator) | Association study of 182 candidate genes in anorexia nervosa.
Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB., Free PMC Article | 06/30/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Identification of hypertension-susceptibility genes and pathways by a systemic multiple candidate gene approach: the millennium genome project for hypertension.
Kohara K, Tabara Y, Nakura J, Imai Y, Ohkubo T, Hata A, Soma M, Nakayama T, Umemura S, Hirawa N, Ueshima H, Kita Y, Ogihara T, Katsuya T, Takahashi N, Tokunaga K, Miki T. | 04/3/2008 |
| GIPC recruits GAIP (RGS19) to attenuate dopamine D2 receptor signaling | GIPC recruits GAIP (RGS19) to attenuate dopamine D2 receptor signaling.
Jeanneteau F, Guillin O, Diaz J, Griffon N, Sokoloff P., Free PMC Article | 01/21/2010 |
| gene structure and transcription regulation | Gene structure, dual-promoters and mRNA alternative splicing of the human and mouse regulator of G protein signaling GAIP/RGS19.
Xie GX, Han X, Ito E, Yanagisawa Y, Maruyama K, Sugano S, Suzuki Y, Wang Y, Gabriel A, Stevens SK, Mitchell J, Sharma M, Palmer PP. | 01/21/2010 |