| E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma. | E3 ubiquitin ligase CHIP interacts with transferrin receptor 1 for degradation and promotes cell proliferation through inhibiting ferroptosis in hepatocellular carcinoma.
Shao M, Qi K, Wang L, Yu X, Zhang Q, Yu L, Wang L, Yang C, Fan L. | 04/12/2024 |
| E3 ubiquitin ligase STUB1 affects the mTORC1 pathway through p62 and participates in regulating the differentiation of follicular helper T cells in rheumatoid arthritis. | E3 ubiquitin ligase STUB1 affects the mTORC1 pathway through p62 and participates in regulating the differentiation of follicular helper T cells in rheumatoid arthritis.
Wang W, Yang Y, Shi Y, Xiang T, Xie J. | 10/11/2023 |
| Degradation of CDK9 by Ubiquitin E3 Ligase STUB1 Regulates P-TEFb Level and Its Functions for Global Target Gene Expression within Mammalian Cells. | Degradation of CDK9 by Ubiquitin E3 Ligase STUB1 Regulates P-TEFb Level and Its Functions for Global Target Gene Expression within Mammalian Cells.
Basu S, Nandy A, Ghosh A, Mall DP, Biswas D., | 09/20/2023 |
| STUB1/CHIP: New insights in cancer and immunity. | STUB1/CHIP: New insights in cancer and immunity.
Liu Y, Zhou H, Tang X. | 08/17/2023 |
| Complex Ataxia-Dementia Phenotype in Patients with Digenic TBP/STUB1 Spinocerebellar Ataxia. | Complex Ataxia-Dementia Phenotype in Patients with Digenic TBP/STUB1 Spinocerebellar Ataxia.
Nanetti L, Magri S, Fichera M, Castaldo A, Nigri A, Pinardi C, Mongelli A, Sarro L, Pareyson D, Grisoli M, Gellera C, Di Bella D, Mariotti C, Taroni F. | 04/21/2023 |
| Intermediate repeat expansions of TBP and STUB1: Genetic modifier or pure digenic inheritance in spinocerebellar ataxias? | Intermediate repeat expansions of TBP and STUB1: Genetic modifier or pure digenic inheritance in spinocerebellar ataxias?
Barbier M, Davoine CS, Petit E, Porché M, Guillot-Noel L, Sayah S, Fauret AL, Neau JP, Guyant-Maréchal L, Deffond D, Tranchant C, Goizet C, Coarelli G, Castrioto A, Klebe S, Ewenczyk C, Heinzmann A, Charles P, Tchikviladzé M, Van Broeckhoven C, Brice A, Durr A. | 02/28/2023 |
| VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4. | VEZF1, destabilized by STUB1, affects cellular growth and metastasis of hepatocellular carcinoma by transcriptionally regulating PAQR4.
Shi X, Zhao P, Zhao G. | 02/22/2023 |
| KDM1A-mediated upregulation of METTL3 ameliorates Alzheimer's disease via enhancing autophagic clearance of p-Tau through m6A-dependent regulation of STUB1. | KDM1A-mediated upregulation of METTL3 ameliorates Alzheimer's disease via enhancing autophagic clearance of p-Tau through m6A-dependent regulation of STUB1.
Tang Z, Cao J, Yao J, Fan X, Zhao J, Zhao M, Duan Q, Han B, Duan S. | 01/21/2023 |
| CHIP induces ubiquitination and degradation of HMGB1 to regulate glycolysis in ovarian endometriosis. | CHIP induces ubiquitination and degradation of HMGB1 to regulate glycolysis in ovarian endometriosis.
Sun Y, Wang Q, Wang M, Sun F, Qiao P, Jiang A, Ren C, Yu Z, Yang T. | 12/31/2022 |
| CHIP: A Co-chaperone for Degradation by the Proteasome and Lysosome. | CHIP: A Co-chaperone for Degradation by the Proteasome and Lysosome.
Chakraborty A, Edkins AL. | 12/31/2022 |
| E3 ubiquitin ligases STUB1/CHIP contributes to the Th17/Treg imbalance via the ubiquitination of aryl hydrocarbon receptor in rheumatoid arthritis. | E3 ubiquitin ligases STUB1/CHIP contributes to the Th17/Treg imbalance via the ubiquitination of aryl hydrocarbon receptor in rheumatoid arthritis.
Wang W, Xiang T, Yang Y, Wang Z, Xie J., Free PMC Article | 10/8/2022 |
| A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing. | A dimer-monomer switch controls CHIP-dependent substrate ubiquitylation and processing.
Balaji V, Müller L, Lorenz R, Kevei É, Zhang WH, Santiago U, Gebauer J, Llamas E, Vilchez D, Camacho CJ, Pokrzywa W, Hoppe T. | 09/17/2022 |
| STUB1 is an intracellular checkpoint for interferon gamma sensing. | STUB1 is an intracellular checkpoint for interferon gamma sensing.
Ng S, Lim S, Sim ACN, Mangadu R, Lau A, Zhang C, Martinez SB, Chandramohan A, Lim UM, Ho SSW, Chang SC, Gopal P, Hong LZ, Schwaid A, Fernandis AZ, Loboda A, Li C, Phan U, Henry B, Partridge AW., Free PMC Article | 08/27/2022 |
| STUB1-SMYD2 Axis Regulates Drug Resistance in Glioma cells. | STUB1-SMYD2 Axis Regulates Drug Resistance in Glioma cells.
Pan K, Hu B, Wang L, Yuan J, Xu W. | 08/27/2022 |
| Regulation of STUB1 expression and its biological significance in mouse Sertoli cells. | Regulation of STUB1 expression and its biological significance in mouse Sertoli cells.
Li T, Zheng C, Han WJ, Chen ZZ. | 06/25/2022 |
| The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP. | The molecular basis of spinocerebellar ataxia type 48 caused by a de novo mutation in the ubiquitin ligase CHIP.
Umano A, Fang K, Qu Z, Scaglione JB, Altinok S, Treadway CJ, Wick ET, Paulakonis E, Karunanayake C, Chou S, Bardakjian TM, Gonzalez-Alegre P, Page RC, Schisler JC, Brown NG, Yan D, Scaglione KM., Free PMC Article | 06/11/2022 |
| Ubiquitin ligase STUB1 destabilizes IFNgamma-receptor complex to suppress tumor IFNgamma signaling. | Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling.
Apriamashvili G, Vredevoogd DW, Krijgsman O, Bleijerveld OB, Ligtenberg MA, de Bruijn B, Boshuizen J, Traets JJH, D'Empaire Altimari D, van Vliet A, Lin CP, Visser NL, Londino JD, Sanchez-Hodge R, Oswalt LE, Altinok S, Schisler JC, Altelaar M, Peeper DS., Free PMC Article | 04/23/2022 |
| Digenic inheritance of STUB1 variants and TBP polyglutamine expansions explains the incomplete penetrance of SCA17 and SCA48. | Digenic inheritance of STUB1 variants and TBP polyglutamine expansions explains the incomplete penetrance of SCA17 and SCA48.
Magri S, Nanetti L, Gellera C, Sarto E, Rizzo E, Mongelli A, Ricci B, Fancellu R, Sambati L, Cortelli P, Brusco A, Bruzzone MG, Mariotti C, Di Bella D, Taroni F. | 03/26/2022 |
| Indeterminate and oncogenic potential: CHIP vs CHOP mutations in AML with NPM1 alteration. | Indeterminate and oncogenic potential: CHIP vs CHOP mutations in AML with NPM1 alteration.
Cappelli LV, Meggendorfer M, Baer C, Nadarajah N, Hutter S, Jeromin S, Dicker F, Kern W, Haferlach T, Haferlach C, Höllein A., Free PMC Article | 02/19/2022 |
| One DNA Methylation Regulates CHIP Gene Expression of Human Breast Cancer and Predicts Recurrence. | One DNA Methylation Regulates CHIP Gene Expression of Human Breast Cancer and Predicts Recurrence.
Gohno T, Hanamura T, Kurosumi M, Takei H, Yamaguchi Y, Hayashi SI. | 02/12/2022 |
| CHIP-mediated CIB1 ubiquitination regulated epithelial-mesenchymal transition and tumor metastasis in lung adenocarcinoma. | CHIP-mediated CIB1 ubiquitination regulated epithelial-mesenchymal transition and tumor metastasis in lung adenocarcinoma.
Liu Y, Zhou Y, Zhang P, Li X, Duan C, Zhang C., Free PMC Article | 01/22/2022 |
| PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins. | PKM2 compensates for proteasome dysfunction by mediating the formation of the CHIP-HSP70-BAG3 complex and the aggregation of ubiquitinated proteins.
Zhang C, Tang Q, Xia H, Xu H, Bi F. | 01/15/2022 |
| Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation. | Adaptor SH3BGRL promotes breast cancer metastasis through PFN1 degradation by translational STUB1 upregulation.
Zhang S, Guo X, Liu X, Zhong Z, Yang S, Wang H. | 01/1/2022 |
| Clinical and functional characterization of a novel STUB1 frameshift mutation in autosomal dominant spinocerebellar ataxia type 48 (SCA48). | Clinical and functional characterization of a novel STUB1 frameshift mutation in autosomal dominant spinocerebellar ataxia type 48 (SCA48).
Chen HY, Hsu CL, Lin HY, Lin YF, Tsai SF, Ho YJ, Li YR, Tsai JW, Teng SC, Lin CH., Free PMC Article | 11/27/2021 |
| STUB1/CHIP promotes ubiquitination and degradation of HIV-1 Vif to restore the cellular level of APOBEC3G protein. | STUB1/CHIP promotes ubiquitination and degradation of HIV-1 Vif to restore the cellular level of APOBEC3G protein.
Ali A, Kumar V, Banerjea AC. | 11/22/2021 |