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    HMGB2 high mobility group B2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838658, updated on 15-Feb-2024

    Summary

    Gene symbol
    HMGB2
    Gene description
    high mobility group B2
    Primary source
    Araport:AT1G20693
    Locus tag
    AT1G20693
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    high mobility group B2; HIGH MOBILITY GROUP BETA 1; HMG BETA 1; NFD02; NFD2; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 02; NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 2
    Summary
    Encodes a protein belonging to the subgroup of HMGB (high mobility group B) proteins that have a distinctive DNA-binding motif, the HMG-box domain. The motif confers non-sequence specific interaction with linear DNA and structure-specific binding to distorted DNA sites. The HMGB proteins are involved in the assembly of nucleoprotein complexes. Can be phosphorylated by CK2alpha.
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    Genomic context

    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (7176747..7178895)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene SWI-SNF-related chromatin binding protein Neighboring gene ncRNA Neighboring gene high mobility group B3 Neighboring gene WUSCHEL related homeobox 14

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    NM_001035997.1
    NM_001084100.1
    NM_101920.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables chromatin binding TAS
    Traceable Author Statement
    more info
    PubMed 
    enables structural constituent of chromatin TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of chromatin TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    high mobility group B2
    NP_001031074.1
    • high mobility group B2 (HMGB2); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910), High mobility group, HMG1/HMG2, subgroup (InterPro:IPR000135); BEST Arabidopsis thaliana protein match is: high mobility group B3 (TAIR:AT1G20696.3); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001077569.1
    • high mobility group B2 (HMGB2); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910), High mobility group, HMG1/HMG2, subgroup (InterPro:IPR000135); BEST Arabidopsis thaliana protein match is: high mobility group B3 (TAIR:AT1G20696.3); Has 7109 Blast hits to 6235 proteins in 712 species: Archae - 0; Bacteria - 5; Metazoa - 5360; Fungi - 490; Plants - 580; Viruses - 7; Other Eukaryotes - 667 (source: NCBI BLink).
    NP_564123.1
    • high mobility group B2 (HMGB2); FUNCTIONS IN: chromatin binding, structural constituent of chromatin, DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910), High mobility group, HMG1/HMG2, subgroup (InterPro:IPR000135); BEST Arabidopsis thaliana protein match is: high mobility group B3 (TAIR:AT1G20696.3); Has 7209 Blast hits to 6316 proteins in 714 species: Archae - 2; Bacteria - 5; Metazoa - 5374; Fungi - 532; Plants - 604; Viruses - 9; Other Eukaryotes - 683 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7176747..7178895
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_101920.3NP_564123.1  high mobility group B2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564123.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8MQZ3, O49596, Q2V4M2, Q9LM85
      UniProtKB/TrEMBL
      A0A178WQA7, A0A5S9VCX2, A0A654ECF0
      Conserved Domains (1) summary
      pfam00505
      Location:38106
      HMG_box; HMG (high mobility group) box
    2. NM_001084100.1NP_001077569.1  high mobility group B2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077569.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WNE2, A0A7G2DS12
      Conserved Domains (1) summary
      pfam00505
      Location:38106
      HMG_box; HMG (high mobility group) box
    3. NM_001035997.1NP_001031074.1  high mobility group B2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031074.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WNE2, A0A7G2DS12
      Conserved Domains (1) summary
      pfam00505
      Location:38106
      HMG_box; HMG (high mobility group) box