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    PPa2 pyrophosphorylase 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816338, updated on 15-Oct-2023

    Summary

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    Gene symbol
    PPa2
    Gene description
    pyrophosphorylase 2
    Primary source
    Araport:AT2G18230
    Locus tag
    AT2G18230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtPPa2; pyrophosphorylase 2; T30D6.26; T30D6_26
    Summary
    Encodes a protein that might have inorganic pyrophosphatase activity.
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    Genomic context

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    See PPa2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    9
    Sequence:
    Chromosome: 2; NC_003071.7 (7931923..7934353, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Noc2p family Neighboring gene Rer1 family protein Neighboring gene alpha/beta-Hydrolases superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of an Arabidopsis inorganic pyrophosphatase capable of being imported into chloroplasts. Schulze S, et al. FEBS Lett, 2004 May 7. PMID 15135060
    2. Vacuolar H(+)-Pyrophosphatase and Cytosolic Soluble Pyrophosphatases Cooperatively Regulate Pyrophosphate Levels in Arabidopsis thaliana. Segami S, et al. Plant Cell, 2018 May. PMID 29691313, Free PMC Article
    3. Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. George GM, et al. Plant Physiol, 2010 Sep. PMID 20605913, Free PMC Article
    4. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article
    5. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_127380.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables inorganic diphosphate phosphatase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables inorganic diphosphate phosphatase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell wall pectin metabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within cell wall thickening IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in phosphate-containing compound metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    pyrophosphorylase 2
    NP_179415.1
    • pyrophosphorylase 2 (PPa2); FUNCTIONS IN: inorganic diphosphatase activity, pyrophosphatase activity; INVOLVED IN: phosphate metabolic process, metabolic process; LOCATED IN: membrane, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Inorganic pyrophosphatase (InterPro:IPR008162); BEST Arabidopsis thaliana protein match is: pyrophosphorylase 4 (TAIR:AT3G53620.1); Has 5938 Blast hits to 5938 proteins in 1818 species: Archae - 171; Bacteria - 4270; Metazoa - 244; Fungi - 258; Plants - 268; Viruses - 0; Other Eukaryotes - 727 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      7931923..7934353 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127380.4 → NP_179415.1  pyrophosphorylase 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179415.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P21216, Q8L988, Q9ZPV6
      UniProtKB/TrEMBL
      A0A178VY12, A0A5S9WYY7
      Conserved Domains (1) summary
      PLN02373
      Location:31 → 218
      PLN02373; soluble inorganic pyrophosphatase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P21216.2

    Gene LinkOut

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