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    znf740b zinc finger protein 740b [ Danio rerio (zebrafish) ]

    Gene ID: 767693, updated on 27-Mar-2024

    Summary

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    Official Symbol
    znf740bprovided by ZNC
    Official Full Name
    zinc finger protein 740bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-660
    See related
    Ensembl:ENSDARG00000061174 AllianceGenome:ZFIN:ZDB-GENE-060929-660
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    znf740; zgc:153696
    Summary
    Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZNF740 (zinc finger protein 740). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    See znf740b in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (36401456..36418050, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (36302738..36319252, complement)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene nuclear factor, erythroid 2 Neighboring gene COPI coat complex subunit zeta 1 Neighboring gene uncharacterized LOC103909707 Neighboring gene cysteine sulfinic acid decarboxylase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain. Sreenivasan R, et al. PLoS One, 2008 Mar 12. PMID 18335061, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC153696

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 740; zinc finger protein 740b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076631.1 → NP_001070099.1  zinc finger protein 740b

      See identical proteins and their annotated locations for NP_001070099.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124428
      UniProtKB/TrEMBL
      Q08C35
      Conserved Domains (2) summary
      sd00017
      Location:113 → 133
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:153 → 178
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      36401456..36418050 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021469848.1 → XP_021325523.1  zinc finger protein 740 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B9H4, F1QPP4
      Related
      ENSDARP00000113405.1, ENSDART00000132273.4
      Conserved Domains (1) summary
      sd00017
      Location:140 → 160
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_005162390.4 → XP_005162447.1  zinc finger protein 740 isoform X1

      See identical proteins and their annotated locations for XP_005162447.1

      UniProtKB/TrEMBL
      A0A8M2B9H4, F1QPP4
      Conserved Domains (1) summary
      sd00017
      Location:140 → 160
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_005162391.4 → XP_005162448.1  zinc finger protein 740 isoform X2

      See identical proteins and their annotated locations for XP_005162448.1

      UniProtKB/TrEMBL
      Q08C35
      Conserved Domains (2) summary
      sd00017
      Location:113 → 133
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:153 → 178
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein
    Heading Accession and Version

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