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    Tmem201 transmembrane protein 201 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 691426, updated on 11-Apr-2024

    Summary

    Official Symbol
    Tmem201provided by RGD
    Official Full Name
    transmembrane protein 201provided by RGD
    Primary source
    RGD:1583947
    See related
    Ensembl:ENSRNOG00000023152 AllianceGenome:RGD:1583947
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable actin filament binding activity and lamin binding activity. Predicted to be involved in several processes, including centrosome localization; nuclear migration along microtubule; and protein localization to nuclear envelope. Predicted to act upstream of or within fibroblast migration and nuclear migration. Predicted to be located in nuclear envelope. Predicted to be integral component of nuclear inner membrane. Predicted to be active in nuclear membrane. Predicted to colocalize with cortical endoplasmic reticulum and spindle pole centrosome. Orthologous to human TMEM201 (transmembrane protein 201). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 37.1), Muscle (RPKM 28.6) and 9 other tissues See more
    Orthologs
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    Genomic context

    Location:
    5q36
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (165449270..165471901, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (160166240..160188874, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (166672700..166695288, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene calsyntenin 1 Neighboring gene phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta Neighboring gene uncharacterized LOC120103039 Neighboring gene solute carrier family 25 member 33 Neighboring gene uncharacterized LOC102548220 Neighboring gene ribosomal protein S2, pseudogene 44

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lamin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables lamin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in centrosome localization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within fibroblast migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear envelope organization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within nuclear migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear migration along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein localization to nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cortical endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear inner membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle pole centrosome ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      165449270..165471901 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001078224.7XP_001078224.2  transmembrane protein 201

      See identical proteins and their annotated locations for XP_001078224.2

      UniProtKB/TrEMBL
      D3ZBW3
      Related
      ENSRNOP00000048083.5
      Conserved Domains (2) summary
      pfam09779
      Location:47169
      Ima1_N; Ima1 N-terminal domain
      pfam10476
      Location:192379
      DUF2448; Protein of unknown function C-terminus (DUF2448)