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    IGFBP6 insulin like growth factor binding protein 6 [ Canis lupus familiaris (dog) ]

    Gene ID: 607374, updated on 5-Mar-2024

    Summary

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    Official Symbol
    IGFBP6provided by VGNC
    Official Full Name
    insulin like growth factor binding protein 6provided by VGNC
    Primary source
    VGNC:VGNC:41907
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 27
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 27 NC_051831.1 (2067593..2071467, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 27 NC_006609.4 (44181845..44185650)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 27 NC_049248.1 (44580850..44584731)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 27 NC_049287.1 (2084643..2088505, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 27 NC_049768.1 (2071186..2075014, complement)

    Chromosome 27 - NC_051831.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S17-like Neighboring gene sterol O-acyltransferase 2 Neighboring gene SPRY domain containing 3 Neighboring gene uncharacterized LOC111092793 Neighboring gene uncharacterized LOC102156972 Neighboring gene tensin 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables fibronectin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables insulin-like growth factor I binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables insulin-like growth factor II binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of insulin-like growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    insulin-like growth factor-binding protein 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051831.1 Reference ROS_Cfam_1.0

      Range
      2067593..2071467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038437851.1 → XP_038293779.1  insulin-like growth factor-binding protein 6

      UniProtKB/TrEMBL
      A0A8C0LAF8, A0A8C0Z4R8
      Conserved Domains (2) summary
      smart00121
      Location:26 → 98
      IB; Insulin growth factor-binding protein homologues
      pfam00086
      Location:161 → 227
      Thyroglobulin_1; Thyroglobulin type-1 repeat

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049287.1 Alternate UMICH_Zoey_3.1

      Range
      2084643..2088505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038514270.1 → XP_038370198.1  insulin-like growth factor-binding protein 6

      Conserved Domains (2) summary
      smart00121
      Location:26 → 98
      IB; Insulin growth factor-binding protein homologues
      pfam00086
      Location:161 → 227
      Thyroglobulin_1; Thyroglobulin type-1 repeat

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049768.1 Alternate UNSW_CanFamBas_1.0

      Range
      2071186..2075014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038640322.1 → XP_038496250.1  insulin-like growth factor-binding protein 6

      Conserved Domains (2) summary
      smart00121
      Location:26 → 98
      IB; Insulin growth factor-binding protein homologues
      pfam00086
      Location:161 → 227
      Thyroglobulin_1; Thyroglobulin type-1 repeat

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049248.1 Alternate UU_Cfam_GSD_1.0

      Range
      44580850..44584731
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038576176.1 → XP_038432104.1  insulin-like growth factor-binding protein 6

      UniProtKB/TrEMBL
      A0A8C0LAF8, A0A8C0Z4R8
      Conserved Domains (2) summary
      smart00121
      Location:26 → 98
      IB; Insulin growth factor-binding protein homologues
      pfam00086
      Location:161 → 227
      Thyroglobulin_1; Thyroglobulin type-1 repeat

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006609.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      44181845..44185650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_853380.6 → XP_858473.2  insulin-like growth factor-binding protein 6

      UniProtKB/TrEMBL
      A0A8C0LAF8, A0A8C0Z4R8
      Conserved Domains (2) summary
      smart00121
      Location:26 → 98
      IB; Insulin growth factor-binding protein homologues
      pfam00086
      Location:161 → 227
      Thyroglobulin_1; Thyroglobulin type-1 repeat
    Nucleotide Protein
    Heading Accession and Version

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