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    ARRB2 arrestin beta 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 607262, updated on 5-Mar-2024

    Summary

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    Official Symbol
    ARRB2provided by VGNC
    Official Full Name
    arrestin beta 2provided by VGNC
    Primary source
    VGNC:VGNC:38137
    See related
    Ensembl:ENSCAFG00845016585
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (31934052..31943706, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (31968270..31977918, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (32036284..32045935, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (31900361..31910009, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (31860046..31869691, complement)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene zinc finger MYND-type containing 15 Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene mediator complex subunit 11 Neighboring gene proline, glutamate and leucine rich protein 1 Neighboring gene MICOS complex subunit MIC26-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables angiotensin receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor internalization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    beta-arrestin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      31934052..31943706 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038665312.1 → XP_038521240.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    2. XM_038665311.1 → XP_038521239.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    3. XM_038665314.1 → XP_038521242.1  beta-arrestin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PVH8, A0A8C0QZ66, A0A8I3NX93, A0A8I3RZF8
      Related
      ENSCAFP00845023131.1, ENSCAFT00845029433.1
      Conserved Domains (2) summary
      smart01017
      Location:194 → 349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19 → 175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    4. XM_038665313.1 → XP_038521241.1  beta-arrestin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:203 → 358
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 184
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    5. XM_038665310.1 → XP_038521238.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    6. XM_038665315.1 → XP_038521243.1  beta-arrestin-2 isoform X4

      Conserved Domains (2) summary
      smart01017
      Location:103 → 258
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:28 → 84
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      31900361..31910009 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038475416.1 → XP_038331344.1  beta-arrestin-2 isoform X1

      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    2. XM_038475415.1 → XP_038331343.1  beta-arrestin-2 isoform X1

      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    3. XM_038475418.1 → XP_038331346.1  beta-arrestin-2 isoform X3

      Conserved Domains (2) summary
      smart01017
      Location:194 → 349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19 → 175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    4. XM_038475417.1 → XP_038331345.1  beta-arrestin-2 isoform X2

      Conserved Domains (2) summary
      smart01017
      Location:203 → 358
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 184
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    5. XM_038475414.1 → XP_038331342.1  beta-arrestin-2 isoform X1

      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    6. XM_038475419.1 → XP_038331347.1  beta-arrestin-2 isoform X4

      Conserved Domains (2) summary
      smart01017
      Location:103 → 258
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:28 → 84
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      31860046..31869691 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038600778.1 → XP_038456706.1  beta-arrestin-2 isoform X1

      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    2. XM_038600777.1 → XP_038456705.1  beta-arrestin-2 isoform X1

      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    3. XM_038600780.1 → XP_038456708.1  beta-arrestin-2 isoform X3

      Conserved Domains (2) summary
      smart01017
      Location:194 → 349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19 → 175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    4. XM_038600779.1 → XP_038456707.1  beta-arrestin-2 isoform X2

      Conserved Domains (2) summary
      smart01017
      Location:203 → 358
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 184
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    5. XM_038600776.1 → XP_038456704.1  beta-arrestin-2 isoform X1

      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    6. XM_038600781.1 → XP_038456709.1  beta-arrestin-2 isoform X4

      Conserved Domains (2) summary
      smart01017
      Location:103 → 258
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:28 → 84
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      32036284..32045935 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038536584.1 → XP_038392512.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    2. XM_038536583.1 → XP_038392511.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    3. XM_038536586.1 → XP_038392514.1  beta-arrestin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PVH8, A0A8C0QZ66, A0A8I3NX93, A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:194 → 349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19 → 175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    4. XM_038536585.1 → XP_038392513.1  beta-arrestin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:203 → 358
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 184
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    5. XM_038536582.1 → XP_038392510.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8I3RZF8
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    6. XM_038536587.1 → XP_038392515.1  beta-arrestin-2 isoform X4

      Conserved Domains (2) summary
      smart01017
      Location:103 → 258
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:28 → 84
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      31968270..31977918 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038514333.1 → XP_038370261.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8P0NHC5
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    2. XM_038514330.1 → XP_038370258.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8P0NHC5
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    3. XM_038514340.1 → XP_038370268.1  beta-arrestin-2 isoform X3

      UniProtKB/TrEMBL
      A0A8P0NHC5, A0A8P0SXL6
      Conserved Domains (2) summary
      smart01017
      Location:194 → 349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19 → 175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    4. XM_038514337.1 → XP_038370265.1  beta-arrestin-2 isoform X2

      UniProtKB/TrEMBL
      A0A8P0NHC5
      Conserved Domains (2) summary
      smart01017
      Location:203 → 358
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 184
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    5. XM_038514327.1 → XP_038370255.1  beta-arrestin-2 isoform X1

      UniProtKB/TrEMBL
      A0A8P0NHC5
      Conserved Domains (2) summary
      smart01017
      Location:224 → 379
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19 → 205
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain

    6. XM_038514341.1 → XP_038370269.1  beta-arrestin-2 isoform X4

      Conserved Domains (2) summary
      smart01017
      Location:103 → 258
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:28 → 84
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    Nucleotide Protein
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