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    STIM2 stromal interaction molecule 2 [ Bos taurus (cattle) ]

    Gene ID: 541299, updated on 5-Mar-2024

    Summary

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    Official Symbol
    STIM2provided by VGNC
    Official Full Name
    stromal interaction molecule 2provided by VGNC
    Primary source
    VGNC:VGNC:53776
    See related
    BGD:BT25547; Ensembl:ENSBTAG00000019353
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 6 NC_037333.1 (46270843..46456139)

    Chromosome 6 - NC_037333.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 19 Neighboring gene uncharacterized LOC112447154 Neighboring gene large ribosomal subunit protein eL22-like Neighboring gene nucleolar protein 56-like

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium channel regulator activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in activation of store-operated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in intracellular calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in store-operated calcium entry IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    stromal interaction molecule 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037333.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46270843..46456139
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005207821.5 → XP_005207878.1  stromal interaction molecule 2 isoform X2

      See identical proteins and their annotated locations for XP_005207878.1

      UniProtKB/TrEMBL
      E1BET0
      Related
      ENSBTAP00000081999.1, ENSBTAT00000126606.1
      Conserved Domains (3) summary
      cd09574
      Location:221 → 294
      SAM_STIM2; SAM domain of STIM2 subfamily proteins
      smart00454
      Location:222 → 286
      SAM; Sterile alpha motif
      pfam16533
      Location:437 → 534
      SOAR; STIM1 Orai1-activating region

    2. XM_002688161.7 → XP_002688207.2  stromal interaction molecule 2 isoform X1

      See identical proteins and their annotated locations for XP_002688207.2

      Related
      ENSBTAP00000044394.5, ENSBTAT00000047170.5
      Conserved Domains (3) summary
      cd09574
      Location:221 → 294
      SAM_STIM2; SAM domain of STIM2 subfamily proteins
      smart00454
      Location:222 → 286
      SAM; Sterile alpha motif
      pfam16533
      Location:437 → 542
      SOAR; STIM1 Orai1-activating region

    3. XM_005207822.5 → XP_005207879.1  stromal interaction molecule 2 isoform X3

      See identical proteins and their annotated locations for XP_005207879.1

      Related
      ENSBTAP00000080883.1, ENSBTAT00000092467.1
      Conserved Domains (3) summary
      cd09574
      Location:221 → 294
      SAM_STIM2; SAM domain of STIM2 subfamily proteins
      smart00454
      Location:222 → 286
      SAM; Sterile alpha motif
      cl17033
      Location:405 → 486
      SOAR; STIM1 Orai1-activating region

    4. XM_024993529.2 → XP_024849297.1  stromal interaction molecule 2 isoform X4

      Related
      ENSBTAP00000092388.1, ENSBTAT00000106606.1
      Conserved Domains (3) summary
      cd09574
      Location:79 → 152
      SAM_STIM2; SAM domain of STIM2 subfamily proteins
      pfam16533
      Location:295 → 400
      SOAR; STIM1 Orai1-activating region
      cl27055
      Location:197 → 377
      MutS_III; MutS domain III
    Nucleotide Protein Strain
    Heading Accession and Version

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