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    NPHS1 NPHS1 adhesion molecule, nephrin [ Bos taurus (cattle) ]

    Gene ID: 519706, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NPHS1provided by VGNC
    Official Full Name
    NPHS1 adhesion molecule, nephrinprovided by VGNC
    Primary source
    VGNC:VGNC:50232
    See related
    BGD:BT20918; Ensembl:ENSBTAG00000007821
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 18 NC_037345.1 (46533476..46556234, complement)

    Chromosome 18 - NC_037345.1Genomic Context describing neighboring genes Neighboring gene inactive serine/threonine-protein kinase TEX14-like Neighboring gene proline dehydrogenase 2 Neighboring gene U6 spliceosomal RNA Neighboring gene kirre like nephrin family adhesion molecule 2 Neighboring gene amyloid beta precursor like protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037345.1 Chromosome 18 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell-cell junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nephrin
    Names
    NPHS1, nephrin
    nephrosis 1, congenital, Finnish type (nephrin)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001192512.1 → NP_001179441.1  nephrin precursor

      See identical proteins and their annotated locations for NP_001179441.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000018
      UniProtKB/TrEMBL
      A0A3Q1LYI9
      Related
      ENSBTAP00000010289.6, ENSBTAT00000010289.6
      Conserved Domains (5) summary
      smart00410
      Location:845 → 935
      IG_like; Immunoglobulin like
      pfam00041
      Location:942 → 1023
      fn3; Fibronectin type III domain
      pfam08205
      Location:141 → 228
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:739 → 820
      Ig_3; Immunoglobulin domain
      cl11960
      Location:834 → 942
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037345.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      46533476..46556234 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005218956.5 → XP_005219013.1  nephrin isoform X1

      UniProtKB/TrEMBL
      A0A3Q1LYI9, F1MPI1
      Conserved Domains (5) summary
      smart00410
      Location:845 → 935
      IG_like; Immunoglobulin like
      pfam00041
      Location:942 → 1023
      fn3; Fibronectin type III domain
      pfam08205
      Location:141 → 228
      C2-set_2; CD80-like C2-set immunoglobulin domain
      pfam13927
      Location:739 → 820
      Ig_3; Immunoglobulin domain
      cl11960
      Location:834 → 942
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version

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