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    DDB2 damage specific DNA binding protein 2 [ Bos taurus (cattle) ]

    Gene ID: 519357, updated on 4-Apr-2024

    Summary

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    Official Symbol
    DDB2provided by VGNC
    Official Full Name
    damage specific DNA binding protein 2provided by VGNC
    Primary source
    VGNC:VGNC:27942
    See related
    BGD:BT14135; Ensembl:ENSBTAG00000020999
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 15
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 15 NC_037342.1 (77097900..77118222)

    Chromosome 15 - NC_037342.1Genomic Context describing neighboring genes Neighboring gene centriolar satellite-associated tubulin polyglutamylase complex regulator 1 Neighboring gene ADP ribosylation factor GTPase activating protein 2 Neighboring gene protein kinase C and casein kinase substrate in neurons 3 Neighboring gene acid phosphatase 2, lysosomal Neighboring gene nuclear receptor subfamily 1 group H member 3 Neighboring gene MAP kinase activating death domain Neighboring gene microRNA mir-2318

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037342.1 Chromosome 15 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC142936

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables damaged DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to UV IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Cul4-RING E3 ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNA damage-binding protein 2
    Names
    damage-specific DNA binding protein 2, 48kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001075788.1 → NP_001069256.1  DNA damage-binding protein 2

      See identical proteins and their annotated locations for NP_001069256.1

      Status: PROVISIONAL

      Source sequence(s)
      BC120440
      UniProtKB/Swiss-Prot
      Q0VBY8
      UniProtKB/TrEMBL
      A0A452DJ02
      Related
      ENSBTAP00000072203.1, ENSBTAT00000086532.2
      Conserved Domains (2) summary
      sd00039
      Location:114 → 153
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:114 → 418
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037342.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      77097900..77118222
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024975278.2 → XP_024831046.1  DNA damage-binding protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A452DJ02
      Related
      ENSBTAP00000027965.4, ENSBTAT00000027965.5
      Conserved Domains (2) summary
      sd00039
      Location:114 → 153
      7WD40; WD40 repeat [structural motif]
      cl25539
      Location:114 → 385
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_059874735.1 → XP_059730718.1  DNA damage-binding protein 2 isoform X2

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0VBY8.1 GenPept UniProtKB/Swiss-Prot:Q0VBY8

    Gene LinkOut

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