UBA6 ubiquitin like modifier activating enzyme 6 [Bos taurus (cattle)] - Gene

Summary

Official Symbol: UBA6provided by VGNC
Official Full Name: ubiquitin like modifier activating enzyme 6provided by VGNC
Primary source: VGNC:VGNC:36565
See related: BGD:BT22858; Ensembl:ENSBTAG00000006837
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Bos taurus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 33

Annotation release	Status	Assembly	Chr	Location
RS_2023_09	current	ARS-UCD2.0 (GCF_002263795.3)	6	NC_037333.1 (83328879..83415785, complement)

Chromosome 6 - NC_037333.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_037333.1 Chromosome 6 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables SUMO activating enzyme activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein sumoylation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of SUMO activating enzyme complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ubiquitin-like modifier-activating enzyme 6

Names: ubiquitin-activating enzyme E1-like 2

NP_001076907.1

EC 6.2.1.45

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001083438.2 → NP_001076907.1 ubiquitin-like modifier-activating enzyme 6

See identical proteins and their annotated locations for NP_001076907.1

Status: PROVISIONAL

Source sequence(s)

BC123526

UniProtKB/TrEMBL

A4FV03, F1ME38

Related

ENSBTAP00000008985.6, ENSBTAT00000008985.7

Conserved Domains (4) summary

cd01490
Location:462 → 1005

Ube1_repeat2; Ubiquitin activating enzyme (E1), repeat 2. E1, a highly conserved small protein present universally in eukaryotic cells, is part of cascade to attach ubiquitin (Ub) covalently to substrate proteins. This cascade consists of activating (E1), conjugating ...

cd01491
Location:43 → 432

Ube1_repeat1; Ubiquitin activating enzyme (E1), repeat 1. E1, a highly conserved small protein present universally in eukaryotic cells, is part of cascade to attach ubiquitin (Ub) covalently to substrate proteins. This cascade consists of activating (E1), conjugating ...

TIGR01408
Location:38 → 1046

Ube1; ubiquitin-activating enzyme E1

pfam16191
Location:299 → 361

E1_4HB; Ubiquitin-activating enzyme E1 four-helix bundle