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    CA5B carbonic anhydrase 5B [ Bos taurus (cattle) ]

    Gene ID: 514494, updated on 5-Mar-2024

    Summary

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    Official Symbol
    CA5Bprovided by VGNC
    Official Full Name
    carbonic anhydrase 5Bprovided by VGNC
    Primary source
    VGNC:VGNC:26655
    See related
    BGD:BT11924; Ensembl:ENSBTAG00000020418
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: X
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) X NC_037357.1 (127724914..127752466, complement)

    Chromosome X - NC_037357.1Genomic Context describing neighboring genes Neighboring gene adaptor related protein complex 1 subunit sigma 2 Neighboring gene zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 Neighboring gene uncharacterized LOC101904527 Neighboring gene carbonic anhydrase 5B, mitochondrial-like Neighboring gene collectrin, amino acid transport regulator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037357.1 Chromosome X Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence evaluation of four pooled-tissue normalized bovine cDNA libraries and construction of a gene index for cattle. Smith TP, et al. Genome Res, 2001 Apr. PMID 11282978, Free PMC Article
    2. Characterization of 954 bovine full-CDS cDNA sequences. Harhay GP, et al. BMC Genomics, 2005 Nov 23. PMID 16305752, Free PMC Article
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables carbonate dehydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    carbonic anhydrase 5B, mitochondrial
    NP_001074377.2
    XP_005228492.1
    XP_005228493.1
    XP_005228494.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080908.3 → NP_001074377.2  carbonic anhydrase 5B, mitochondrial

      See identical proteins and their annotated locations for NP_001074377.2

      Status: VALIDATED

      Source sequence(s)
      NKLS02000030
      UniProtKB/TrEMBL
      F1N5D1
      Related
      ENSBTAP00000027210.4, ENSBTAT00000027210.5
      Conserved Domains (1) summary
      cl00012
      Location:61 → 296
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037357.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      127724914..127752466 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005228437.5 → XP_005228494.1  carbonic anhydrase 5B, mitochondrial isoform X2

      Related
      ENSBTAP00000102027.1, ENSBTAT00000105215.1
      Conserved Domains (1) summary
      cl00012
      Location:61 → 275
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

    2. XM_005228436.5 → XP_005228493.1  carbonic anhydrase 5B, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005228493.1

      UniProtKB/TrEMBL
      F1N5D1
      Conserved Domains (1) summary
      cl00012
      Location:61 → 296
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...

    3. XM_005228435.5 → XP_005228492.1  carbonic anhydrase 5B, mitochondrial isoform X1

      See identical proteins and their annotated locations for XP_005228492.1

      UniProtKB/TrEMBL
      F1N5D1
      Conserved Domains (1) summary
      cl00012
      Location:61 → 296
      alpha_CA; Carbonic anhydrase alpha (vertebrate-like) group. Carbonic anhydrases (CAs) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism: a nucleophilic attack of a zinc-bound hydroxide ion on carbon ...
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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