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    ITGA10 integrin subunit alpha 10 [ Bos taurus (cattle) ]

    Gene ID: 506526, updated on 5-Mar-2024

    Summary

    Official Symbol
    ITGA10provided by VGNC
    Official Full Name
    integrin subunit alpha 10provided by VGNC
    Primary source
    VGNC:VGNC:30311
    See related
    BGD:BT10806; Ensembl:ENSBTAG00000008373
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs
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    Genomic context

    Location:
    chromosome: 3
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 3 NC_037330.1 (21459795..21477566)

    Chromosome 3 - NC_037330.1Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein 8A Neighboring gene gonadotropin releasing hormone receptor 2 Neighboring gene peroxisomal biogenesis factor 11 beta Neighboring gene ankyrin repeat domain 35 Neighboring gene protein inhibitor of activated STAT 3 Neighboring gene nudix hydrolase 17

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037330.1 Chromosome 3 Reference ARS-UCD2.0 Primary Assembly

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables integrin binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion mediated by integrin IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cell-cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in cell-matrix adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in integrin-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in external side of plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    part_of integrin complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    integrin alpha-10
    Names
    integrin, alpha 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205590.1NP_001192519.1  integrin alpha-10 precursor

      See identical proteins and their annotated locations for NP_001192519.1

      Status: PROVISIONAL

      Source sequence(s)
      NKLS02000003
      UniProtKB/TrEMBL
      E1BDD5
      Related
      ENSBTAP00000011023.3, ENSBTAT00000011023.5
      Conserved Domains (3) summary
      smart00191
      Location:545599
      Int_alpha; Integrin alpha (beta-propellor repeats)
      cd01469
      Location:166346
      vWA_integrins_alpha_subunit; Integrins are a class of adhesion receptors that link the extracellular matrix to the cytoskeleton and cooperate with growth factor receptors to promote celll survival, cell cycle progression and cell migration. Integrins consist of an alpha and a beta ...
      pfam08441
      Location:6421050
      Integrin_alpha2; Integrin alpha

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037330.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      21459795..21477566
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_059882736.1XP_059738719.1  integrin alpha-10 isoform X1

    RNA

    1. XR_009493301.1 RNA Sequence