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    CFD complement factor D [ Bos taurus (cattle) ]

    Gene ID: 505647, updated on 5-Mar-2024

    Summary

    Official Symbol
    CFDprovided by VGNC
    Official Full Name
    complement factor Dprovided by VGNC
    Primary source
    VGNC:VGNC:97253
    See related
    Ensembl:ENSBTAG00000048122
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    DF
    Orthologs
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    Genomic context

    See CFD in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 7 NC_037334.1 (43416267..43418803)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene proteinase 3 Neighboring gene elastase, neutrophil expressed Neighboring gene mediator complex subunit 16 Neighboring gene U6 spliceosomal RNA Neighboring gene R3H domain containing 4

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_037334.1 Chromosome 7 Reference ARS-UCD2.0 Primary Assembly

    Pathways from PubChem

    General protein information

    Preferred Names
    complement factor D
    Names
    C3 convertase activator
    D component of complement (adipsin)
    adipsin
    properdin factor D
    NP_001029427.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034255.2NP_001029427.1  complement factor D precursor

      See identical proteins and their annotated locations for NP_001029427.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102479
      UniProtKB/Swiss-Prot
      Q3T0A3
      Related
      ENSBTAP00000055802.1, ENSBTAT00000063284.3
      Conserved Domains (2) summary
      smart00020
      Location:26249
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:27250
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      43416267..43418803
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)