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    SPDEF SAM pointed domain containing ETS transcription factor [ Bos taurus (cattle) ]

    Gene ID: 497620, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SPDEFprovided by VGNC
    Official Full Name
    SAM pointed domain containing ETS transcription factorprovided by VGNC
    Primary source
    VGNC:VGNC:35198
    See related
    BGD:BT29197; Ensembl:ENSBTAG00000021993
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    pdef
    Orthologs
    human mouse all
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    Genomic context

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    See SPDEF in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 23 NC_037350.1 (8591536..8608902, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene protein kinase C and casein kinase substrate in neurons 1 Neighboring gene inflammation and lipid regulator with UBA-like and NBR1-like domains Neighboring gene small nucleolar RNA SNORA70

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037350.1 Chromosome 23 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression analysis of androgen-responsive genes in the prostate of veal calves treated with anabolic hormones. Toffolatti L, et al. Domest Anim Endocrinol, 2006 Jan. PMID 16023321
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SAM pointed domain-containing Ets transcription factor
    Names
    prostate epithelium-specific ETS transcription factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081578.1 → NP_001075047.1  SAM pointed domain-containing Ets transcription factor

      See identical proteins and their annotated locations for NP_001075047.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133366
      UniProtKB/TrEMBL
      A0A3Q1M810, A2VDR4
      Related
      ENSBTAP00000029329.4, ENSBTAT00000029329.5
      Conserved Domains (3) summary
      cd08532
      Location:134 → 214
      SAM_PNT-PDEF-like; Sterile alpha motif (SAM)/Pointed domain of prostate-derived ETS factor
      smart00413
      Location:248 → 334
      ETS; erythroblast transformation specific domain
      cl26386
      Location:1 → 102
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      8591536..8608902 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010818024.4 → XP_010816326.1  SAM pointed domain-containing Ets transcription factor isoform X1

      UniProtKB/TrEMBL
      A0A3Q1M810
      Related
      ENSBTAP00000080698.1, ENSBTAT00000134078.1
      Conserved Domains (3) summary
      cd08532
      Location:134 → 212
      SAM_PNT-PDEF-like; Sterile alpha motif (SAM)/Pointed domain of prostate-derived ETS factor
      smart00413
      Location:232 → 318
      ETS; erythroblast transformation specific domain
      cl26386
      Location:1 → 102
      DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III
    Nucleotide Protein Strain
    Heading Accession and Version

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