U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    NGFR nerve growth factor receptor [ Canis lupus familiaris (dog) ]

    Gene ID: 491071, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    NGFRprovided by VGNC
    Official Full Name
    nerve growth factor receptorprovided by VGNC
    Primary source
    VGNC:VGNC:55650
    See related
    Ensembl:ENSCAFG00845011173
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    chromosome: 9
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (26393929..26416386)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (25057204..25079762)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (25550245..25572703)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (25161801..25184255)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (25420950..25443499)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102151806 Neighboring gene prohibitin 1 Neighboring gene uncharacterized LOC111097372 Neighboring gene neurexophilin 3 Neighboring gene speckle type BTB/POZ protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Multiple motifs regulate apical sorting of p75 via a mechanism that involves dimerization and higher-order oligomerization. Youker RT, et al. Mol Biol Cell, 2013 Jun. PMID 23637462, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Data indicate that wild-type p75-green fluorescent protein forms clusters in the trans-Golgi network (TGN) but not at the plasma membrane.
      Title: Multiple motifs regulate apical sorting of p75 via a mechanism that involves dimerization and higher-order oligomerization.
    Submit: New GeneRIF Correction

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables coreceptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables death receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables nerve growth factor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    tumor necrosis factor receptor superfamily member 16
    Names
    nerve growth factor receptor (TNFR superfamily, member 16)

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      26393929..26416386
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038675121.1 → XP_038531049.1  tumor necrosis factor receptor superfamily member 16 isoform X1

      UniProtKB/TrEMBL
      A0A8C0S459, A0A8I3NE38
      Related
      ENSCAFP00845015506.1, ENSCAFT00845019806.1
      Conserved Domains (3) summary
      cd08311
      Location:423 → 501
      Death_p75NR; Death domain of p75 Neurotrophin Receptor
      cd13416
      Location:113 → 271
      TNFRSF16; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16), also known as p75 neurotrophin receptor (p75NTR) or CD271
      pfam18422
      Location:329 → 366
      TNFR_16_TM; Tumor necrosis factor receptor member 16 trans-membrane domain

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      25161801..25184255
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038484511.1 → XP_038340439.1  tumor necrosis factor receptor superfamily member 16 isoform X1

      Conserved Domains (3) summary
      cd08311
      Location:423 → 501
      Death_p75NR; Death domain of p75 Neurotrophin Receptor
      cd13416
      Location:113 → 271
      TNFRSF16; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16), also known as p75 neurotrophin receptor (p75NTR) or CD271
      pfam18422
      Location:329 → 366
      TNFR_16_TM; Tumor necrosis factor receptor member 16 trans-membrane domain

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      25420950..25443499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038610058.1 → XP_038465986.1  tumor necrosis factor receptor superfamily member 16 isoform X2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      25550245..25572703
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038546030.1 → XP_038401958.1  tumor necrosis factor receptor superfamily member 16 isoform X1

      UniProtKB/TrEMBL
      A0A8C0S459, A0A8I3NE38
      Conserved Domains (3) summary
      cd08311
      Location:423 → 501
      Death_p75NR; Death domain of p75 Neurotrophin Receptor
      cd13416
      Location:113 → 271
      TNFRSF16; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16), also known as p75 neurotrophin receptor (p75NTR) or CD271
      pfam18422
      Location:329 → 366
      TNFR_16_TM; Tumor necrosis factor receptor member 16 trans-membrane domain

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      25057204..25079762
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038619094.1 → XP_038475022.1  tumor necrosis factor receptor superfamily member 16 isoform X3

      UniProtKB/TrEMBL
      A0A8C0S459, A0A8I3NE38
      Conserved Domains (3) summary
      cd08311
      Location:429 → 507
      Death_p75NR; Death domain of p75 Neurotrophin Receptor
      cd13416
      Location:119 → 277
      TNFRSF16; Tumor necrosis factor receptor superfamily member 16 (TNFRSF16), also known as p75 neurotrophin receptor (p75NTR) or CD271
      pfam18422
      Location:335 → 372
      TNFR_16_TM; Tumor necrosis factor receptor member 16 trans-membrane domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Miscellaneous