ARHGAP17 Rho GTPase activating protein 17 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: ARHGAP17provided by VGNC
Official Full Name: Rho GTPase activating protein 17provided by VGNC
Primary source: VGNC:VGNC:38048
See related: Ensembl:ENSCAFG00845000580
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	6	NC_051810.1 (21222691..21315817)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	6	NC_006588.4 (26076872..26171875, complement)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	6	NC_049227.1 (21323131..21417935)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	6	NC_049266.1 (21025615..21120189)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	6	NC_049747.1 (20928650..21023425)

Chromosome 6 - NC_051810.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTPase activator activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of Rac protein signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in intracellular anatomical structure	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: rho GTPase-activating protein 17

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051810.1 Reference ROS_Cfam_1.0

Range

21222691..21315817

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038668805.1 → XP_038524733.1 rho GTPase-activating protein 17 isoform X1

UniProtKB/TrEMBL

A0A8C0L9R9, A0A8C0PYQ5, A0A8C0R541, A0A8I3RP97

Conserved Domains (3) summary

PHA03247
Location:520 → 744

PHA03247; large tegument protein UL36; Provisional

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_038668807.1 → XP_038524735.1 rho GTPase-activating protein 17 isoform X2

UniProtKB/TrEMBL

A0A8C0L9R9, A0A8C0P5T3, A0A8C0R539, A0A8I3ML71

Related

ENSCAFP00845000710.1, ENSCAFT00845000940.1

Conserved Domains (3) summary

PHA03247
Location:520 → 744

PHA03247; large tegument protein UL36; Provisional

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_038668808.1 → XP_038524736.1 rho GTPase-activating protein 17 isoform X3

UniProtKB/TrEMBL

A0A8C0Q6F7, A0A8I3MDA3, A0A8P0P6C0

Related

ENSCAFP00845000774.1, ENSCAFT00845001023.1

Conserved Domains (2) summary

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_038668806.1 → XP_038524734.1 rho GTPase-activating protein 17 isoform X1

UniProtKB/TrEMBL

A0A8C0L9R9, A0A8C0PYQ5, A0A8C0R541, A0A8I3RP97

Related

ENSCAFP00845000757.1, ENSCAFT00845000998.1

Conserved Domains (3) summary

PHA03247
Location:520 → 744

PHA03247; large tegument protein UL36; Provisional

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UMICH_Zoey_3.1

Genomic

NC_049266.1 Alternate UMICH_Zoey_3.1

Range

21025615..21120189

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038478762.1 → XP_038334690.1 rho GTPase-activating protein 17 isoform X4

Conserved Domains (3) summary

PHA03247
Location:520 → 744

PHA03247; large tegument protein UL36; Provisional

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_038478763.1 → XP_038334691.1 rho GTPase-activating protein 17 isoform X5

Conserved Domains (2) summary

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049747.1 Alternate UNSW_CanFamBas_1.0

Range

20928650..21023425

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038604087.1 → XP_038460015.1 rho GTPase-activating protein 17 isoform X6

Conserved Domains (3) summary

PHA03247
Location:520 → 744

PHA03247; large tegument protein UL36; Provisional

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_038604088.1 → XP_038460016.1 rho GTPase-activating protein 17 isoform X7

Conserved Domains (2) summary

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049227.1 Alternate UU_Cfam_GSD_1.0

Range

21323131..21417935

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038540007.1 → XP_038395935.1 rho GTPase-activating protein 17 isoform X8

UniProtKB/TrEMBL

A0A8C0L9R9, A0A8C0LCN7, A0A8C0RRD6, A0A8P0NJ36

Conserved Domains (3) summary

PHA03247
Location:520 → 744

PHA03247; large tegument protein UL36; Provisional

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_038540008.1 → XP_038395936.1 rho GTPase-activating protein 17 isoform X9

UniProtKB/TrEMBL

A0A8C0P3G6, A0A8C0R548, A0A8P0P6C0

Conserved Domains (2) summary

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006588.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

26076872..26171875 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038545744.1 → XP_038401672.1 rho GTPase-activating protein 17 isoform X11

UniProtKB/TrEMBL

A0A8C0P3G6, A0A8C0R548, A0A8P0P6C0

Conserved Domains (2) summary

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
XM_038545741.1 → XP_038401669.1 rho GTPase-activating protein 17 isoform X10

UniProtKB/TrEMBL

A0A8C0L9R9, A0A8C0LCN7, A0A8C0RRD6, A0A8P0NJ36

Conserved Domains (3) summary

PHA03247
Location:520 → 744

PHA03247; large tegument protein UL36; Provisional

cd04386
Location:246 → 446

RhoGAP_nadrin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Nadrin-like proteins. Nadrin, also named Rich-1, has been shown to be involved in the regulation of Ca2+-dependent exocytosis in neurons and recently has been implicated in ...

cl12013
Location:13 → 257

BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature