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    PFAS phosphoribosylformylglycinamidine synthase [ Canis lupus familiaris (dog) ]

    Gene ID: 489490, updated on 5-Mar-2024

    Summary

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    Official Symbol
    PFASprovided by VGNC
    Official Full Name
    phosphoribosylformylglycinamidine synthaseprovided by VGNC
    Primary source
    VGNC:VGNC:44439
    See related
    Ensembl:ENSCAFG00845000288
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See PFAS in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 5 NC_051809.1 (33158221..33179437)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 5 NC_006587.4 (33191282..33212476)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 5 NC_049226.1 (33260701..33281894)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 5 NC_049265.1 (33124973..33146201)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 5 NC_049746.1 (33080723..33102164)

    Chromosome 5 - NC_051809.1Genomic Context describing neighboring genes Neighboring gene transfer RNA isoleucine (anticodon AAU) Neighboring gene CST telomere replication complex component 1 Neighboring gene uncharacterized LOC119875291 Neighboring gene solute carrier family 25 member 35 Neighboring gene RAN guanine nucleotide release factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables phosphoribosylformylglycinamidine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in 'de novo' IMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphoribosylformylglycinamidine synthase
    Names
    phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
    XP_038331566.1
    XP_038331567.1
    XP_038331568.1
    XP_038331569.1
    XP_038371840.1
    XP_038371843.1
    XP_038371853.1
    XP_038371859.1
    XP_038392742.1
    XP_038392743.1
    XP_038392744.1
    XP_038392745.1
    XP_038456892.1
    XP_038456893.1
    XP_038456894.1
    XP_038456895.1
    XP_038521460.1
    XP_038521461.1
    XP_038521462.1
    XP_038521463.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051809.1 Reference ROS_Cfam_1.0

      Range
      33158221..33179437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038665535.1 → XP_038521463.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0LUH9, A0A8C0LW77
      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    2. XM_038665534.1 → XP_038521462.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0LUH9, A0A8C0LW77
      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    3. XM_038665533.1 → XP_038521461.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0LUH9, A0A8C0LW77
      Related
      ENSCAFP00845000318.1, ENSCAFT00845000465.1
      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    4. XM_038665532.1 → XP_038521460.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0LUH9, A0A8C0LW77
      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049265.1 Alternate UMICH_Zoey_3.1

      Range
      33124973..33146201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038475641.1 → XP_038331569.1  phosphoribosylformylglycinamidine synthase

    2. XM_038475640.1 → XP_038331568.1  phosphoribosylformylglycinamidine synthase

    3. XM_038475639.1 → XP_038331567.1  phosphoribosylformylglycinamidine synthase

    4. XM_038475638.1 → XP_038331566.1  phosphoribosylformylglycinamidine synthase

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049746.1 Alternate UNSW_CanFamBas_1.0

      Range
      33080723..33102164
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038600967.1 → XP_038456895.1  phosphoribosylformylglycinamidine synthase

      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    2. XM_038600966.1 → XP_038456894.1  phosphoribosylformylglycinamidine synthase

      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    3. XM_038600965.1 → XP_038456893.1  phosphoribosylformylglycinamidine synthase

      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    4. XM_038600964.1 → XP_038456892.1  phosphoribosylformylglycinamidine synthase

      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049226.1 Alternate UU_Cfam_GSD_1.0

      Range
      33260701..33281894
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038536817.1 → XP_038392745.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0K2E3, A0A8C0LW77, A0A8C0SDW0

    2. XM_038536816.1 → XP_038392744.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0K2E3, A0A8C0LW77, A0A8C0SDW0

    3. XM_038536815.1 → XP_038392743.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0K2E3, A0A8C0LW77, A0A8C0SDW0

    4. XM_038536814.1 → XP_038392742.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0K2E3, A0A8C0LW77, A0A8C0SDW0

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006587.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      33191282..33212476
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038515931.1 → XP_038371859.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0LUH9, A0A8C0LW77
      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    2. XM_038515925.1 → XP_038371853.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0LUH9, A0A8C0LW77
      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    3. XM_038515915.1 → XP_038371843.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0LUH9, A0A8C0LW77
      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

    4. XM_038515912.1 → XP_038371840.1  phosphoribosylformylglycinamidine synthase

      UniProtKB/TrEMBL
      A0A8C0LUH9, A0A8C0LW77
      Conserved Domains (1) summary
      TIGR01735
      Location:7 → 1336
      FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form
    Nucleotide Protein
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