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    PDZD8 PDZ domain containing 8 [ Canis lupus familiaris (dog) ]

    Gene ID: 486909, updated on 11-Apr-2024

    Summary

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    Official Symbol
    PDZD8provided by VGNC
    Official Full Name
    PDZ domain containing 8provided by VGNC
    Primary source
    VGNC:VGNC:44402
    See related
    Ensembl:ENSCAFG00845031054
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 28
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 28 NC_051832.1 (28289062..28383545, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 28 NC_006610.4 (27902798..27997253, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 28 NC_049249.1 (28058685..28153690, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 28 NC_049288.1 (27861675..27945273, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 28 NC_049769.1 (27863751..27958752, complement)

    Chromosome 28 - NC_051832.1Genomic Context describing neighboring genes Neighboring gene potassium two pore domain channel subfamily K member 18 Neighboring gene uncharacterized LOC102155978 Neighboring gene solute carrier family 18 member A2 Neighboring gene uncharacterized LOC111093041 Neighboring gene uncharacterized LOC111092950

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assembly of the β4-Integrin Interactome Based on Proximal Biotinylation in the Presence and Absence of Heterodimerization. Myllymäki SM, et al. Mol Cell Proteomics, 2019 Feb. PMID 30404858, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial calcium ion homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitochondrion-endoplasmic reticulum membrane tethering IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondria-associated endoplasmic reticulum membrane contact site IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PDZ domain-containing protein 8; LOW QUALITY PROTEIN: PDZ domain-containing protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051832.1 Reference ROS_Cfam_1.0

      Range
      28289062..28383545 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038440709.1 → XP_038296637.1  PDZ domain-containing protein 8

      UniProtKB/TrEMBL
      A0A8C0PD34, A0A8I3Q673, A0A8P0SGS5
      Related
      ENSCAFP00845043420.1, ENSCAFT00845055206.1
      Conserved Domains (3) summary
      PHA03247
      Location:531 → 697
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:379 → 456
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd20825
      Location:853 → 908
      C1_PDZD8; protein kinase C conserved region 1 (C1 domain) found in PDZ domain-containing protein 8 (PDZD8) and similar proteins

    RNA

    1. XR_005303818.1 RNA Sequence

    2. XR_005303815.1 RNA Sequence

    3. XR_005303814.1 RNA Sequence

    4. XR_005303813.1 RNA Sequence

    5. XR_005303812.1 RNA Sequence

    6. XR_005303817.1 RNA Sequence

    7. XR_005303816.1 RNA Sequence

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049288.1 Alternate UMICH_Zoey_3.1

      Range
      27861675..27945273 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038515307.1 → XP_038371235.1  LOW QUALITY PROTEIN: PDZ domain-containing protein 8

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049769.1 Alternate UNSW_CanFamBas_1.0

      Range
      27863751..27958752 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038643127.1 → XP_038499055.1  PDZ domain-containing protein 8

    RNA

    1. XR_005414449.1 RNA Sequence

    2. XR_005414446.1 RNA Sequence

    3. XR_005414445.1 RNA Sequence

    4. XR_005414444.1 RNA Sequence

    5. XR_005414443.1 RNA Sequence

    6. XR_005414448.1 RNA Sequence

    7. XR_005414447.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049249.1 Alternate UU_Cfam_GSD_1.0

      Range
      28058685..28153690 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038578915.1 → XP_038434843.1  PDZ domain-containing protein 8

      UniProtKB/TrEMBL
      A0A8C0PD34, A0A8I3Q673, A0A8P0SGS5
      Conserved Domains (3) summary
      PHA03247
      Location:531 → 697
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:379 → 456
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd20825
      Location:853 → 908
      C1_PDZD8; protein kinase C conserved region 1 (C1 domain) found in PDZ domain-containing protein 8 (PDZD8) and similar proteins

    RNA

    1. XR_005380657.1 RNA Sequence

    2. XR_005380654.1 RNA Sequence

    3. XR_005380653.1 RNA Sequence

    4. XR_005380652.1 RNA Sequence

    5. XR_005380651.1 RNA Sequence

    6. XR_005380656.1 RNA Sequence

    7. XR_005380655.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006610.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      27902798..27997253 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_544039.7 → XP_544039.2  PDZ domain-containing protein 8

      UniProtKB/TrEMBL
      A0A8C0PD34, A0A8I3Q673, A0A8P0SGS5
      Conserved Domains (3) summary
      PHA03247
      Location:531 → 697
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:379 → 456
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd20825
      Location:853 → 908
      C1_PDZD8; protein kinase C conserved region 1 (C1 domain) found in PDZ domain-containing protein 8 (PDZD8) and similar proteins

    RNA

    1. XR_002620696.2 RNA Sequence

    2. XR_005315948.1 RNA Sequence

    3. XR_002620695.2 RNA Sequence

    4. XR_002620693.2 RNA Sequence

    5. XR_002620691.2 RNA Sequence

    6. XR_002620694.2 RNA Sequence

    7. XR_002620692.2 RNA Sequence

    Nucleotide Protein
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