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    HSD11B1L hydroxysteroid 11-beta dehydrogenase 1 like [ Canis lupus familiaris (dog) ]

    Gene ID: 485027, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HSD11B1Lprovided by VGNC
    Official Full Name
    hydroxysteroid 11-beta dehydrogenase 1 likeprovided by VGNC
    Primary source
    VGNC:VGNC:41798
    See related
    Ensembl:ENSCAFG00845013008
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human all
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    Genomic context

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    Location:
    chromosome: 20
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 20 NC_051824.1 (54992234..54997427, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 20 NC_006602.4 (54063122..54068434, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 20 NC_049241.1 (54732278..54737590, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 20 NC_049280.1 (54054506..54059817, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 20 NC_049761.1 (54535013..54540328, complement)

    Chromosome 20 - NC_051824.1Genomic Context describing neighboring genes Neighboring gene lon peptidase 1, mitochondrial Neighboring gene ribosomal protein L36 Neighboring gene mitochondrial contact site and cristae organizing system subunit 13 Neighboring gene scaffold attachment factor B Neighboring gene scaffold attachment factor B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hydroxysteroid 11-beta-dehydrogenase 1-like protein
    XP_005633068.1
    XP_005633069.1
    XP_038284887.1
    XP_038284888.1
    XP_038284889.1
    XP_038284890.1
    XP_038284891.1
    XP_038284892.1
    XP_038284893.1
    XP_038284894.1
    XP_038284895.1
    XP_038284896.1
    XP_038284897.1
    XP_038284898.1
    XP_038284899.1
    XP_038311637.1
    XP_038311638.1
    XP_038311639.1
    XP_038311640.1
    XP_038311641.1
    XP_038311642.1
    XP_038311643.1
    XP_038311644.1
    XP_038311645.1
    XP_038311646.1
    XP_038311647.1
    XP_038360521.1
    XP_038360522.1
    XP_038360523.1
    XP_038360524.1
    XP_038360525.1
    XP_038360526.1
    XP_038360527.1
    XP_038360528.1
    XP_038360529.1
    XP_038360530.1
    XP_038360531.1
    XP_038360532.1
    XP_038360533.1
    XP_038423566.1
    XP_038423567.1
    XP_038423568.1
    XP_038423569.1
    XP_038423570.1
    XP_038423571.1
    XP_038423572.1
    XP_038423573.1
    XP_038423574.1
    XP_038423575.1
    XP_038423576.1
    XP_038423577.1
    XP_038423578.1
    XP_038487720.1
    XP_038487721.1
    XP_038487722.1
    XP_038487723.1
    XP_038487724.1
    XP_038487725.1
    XP_038487726.1
    XP_038487727.1
    XP_038487728.1
    XP_038487729.1
    XP_038487730.1
    XP_038487731.1
    XP_038487732.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051824.1 Reference ROS_Cfam_1.0

      Range
      54992234..54997427 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038428964.1 → XP_038284892.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_038428967.1 → XP_038284895.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. XM_038428968.1 → XP_038284896.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X4

      Conserved Domains (1) summary
      cl21454
      Location:131 → 293
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_038428970.1 → XP_038284898.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X6

    5. XM_038428963.1 → XP_038284891.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    6. XM_038428962.1 → XP_038284890.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    7. XM_038428961.1 → XP_038284889.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    8. XM_038428959.1 → XP_038284887.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    9. XM_038428960.1 → XP_038284888.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    10. XM_038428971.1 → XP_038284899.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X7

      Conserved Domains (1) summary
      cl21454
      Location:49 → 166
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    11. XM_038428969.1 → XP_038284897.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X5

      UniProtKB/TrEMBL
      A0A8C0L3A7, A0A8C0PC76, A0A8P0PBL5
      Conserved Domains (1) summary
      cl21454
      Location:40 → 281
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    12. XM_038428965.1 → XP_038284893.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Conserved Domains (1) summary
      cl21454
      Location:40 → 236
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    13. XM_038428966.1 → XP_038284894.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Related
      ENSCAFP00845018154.1, ENSCAFT00845023154.1
      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049280.1 Alternate UMICH_Zoey_3.1

      Range
      54054506..54059817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038504598.1 → XP_038360526.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    2. XM_038504601.1 → XP_038360529.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. XM_038504602.1 → XP_038360530.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X4

    4. XM_038504604.1 → XP_038360532.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X6

    5. XM_038504597.1 → XP_038360525.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    6. XM_038504596.1 → XP_038360524.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    7. XM_038504595.1 → XP_038360523.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    8. XM_038504593.1 → XP_038360521.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    9. XM_038504594.1 → XP_038360522.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

    10. XM_038504605.1 → XP_038360533.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X7

    11. XM_038504603.1 → XP_038360531.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X5

      Conserved Domains (1) summary
      cl21454
      Location:40 → 281
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    12. XM_038504599.1 → XP_038360527.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2

      Conserved Domains (1) summary
      cl21454
      Location:40 → 236
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    13. XM_038504600.1 → XP_038360528.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049761.1 Alternate UNSW_CanFamBas_1.0

      Range
      54535013..54540328 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038631797.1 → XP_038487725.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_038631800.1 → XP_038487728.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. XM_038631801.1 → XP_038487729.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X4

      Conserved Domains (1) summary
      cl21454
      Location:131 → 293
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_038631803.1 → XP_038487731.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X6

    5. XM_038631796.1 → XP_038487724.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    6. XM_038631795.1 → XP_038487723.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    7. XM_038631794.1 → XP_038487722.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    8. XM_038631792.1 → XP_038487720.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    9. XM_038631793.1 → XP_038487721.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    10. XM_038631804.1 → XP_038487732.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X7

      Conserved Domains (1) summary
      cl21454
      Location:49 → 166
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    11. XM_038631802.1 → XP_038487730.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X5

      Conserved Domains (1) summary
      cl21454
      Location:40 → 281
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    12. XM_038631798.1 → XP_038487726.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2

      Conserved Domains (1) summary
      cl21454
      Location:40 → 236
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    13. XM_038631799.1 → XP_038487727.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049241.1 Alternate UU_Cfam_GSD_1.0

      Range
      54732278..54737590 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038567643.1 → XP_038423571.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_038567646.1 → XP_038423574.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. XM_038567647.1 → XP_038423575.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X4

      Conserved Domains (1) summary
      cl21454
      Location:131 → 293
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_038567649.1 → XP_038423577.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X6

    5. XM_038567642.1 → XP_038423570.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    6. XM_038567641.1 → XP_038423569.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    7. XM_038567640.1 → XP_038423568.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    8. XM_038567638.1 → XP_038423566.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    9. XM_038567639.1 → XP_038423567.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    10. XM_038567650.1 → XP_038423578.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X7

      Conserved Domains (1) summary
      cl21454
      Location:49 → 166
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    11. XM_038567648.1 → XP_038423576.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X5

      UniProtKB/TrEMBL
      A0A8C0L3A7, A0A8C0PC76, A0A8P0PBL5
      Conserved Domains (1) summary
      cl21454
      Location:40 → 281
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    12. XM_038567644.1 → XP_038423572.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Conserved Domains (1) summary
      cl21454
      Location:40 → 236
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    13. XM_038567645.1 → XP_038423573.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006602.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      54063122..54068434 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038455714.1 → XP_038311642.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    2. XM_005633012.3 → XP_005633069.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      See identical proteins and their annotated locations for XP_005633069.1

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    3. XM_038455716.1 → XP_038311644.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X4

      Conserved Domains (1) summary
      cl21454
      Location:131 → 293
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    4. XM_038455718.1 → XP_038311646.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X6

    5. XM_038455713.1 → XP_038311641.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    6. XM_038455712.1 → XP_038311640.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    7. XM_038455711.1 → XP_038311639.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    8. XM_038455709.1 → XP_038311637.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    9. XM_038455710.1 → XP_038311638.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X1

      Conserved Domains (1) summary
      cl21454
      Location:131 → 248
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    10. XM_038455719.1 → XP_038311647.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X7

      Conserved Domains (1) summary
      cl21454
      Location:49 → 166
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    11. XM_038455717.1 → XP_038311645.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X5

      UniProtKB/TrEMBL
      A0A8C0L3A7, A0A8C0PC76, A0A8P0PBL5
      Conserved Domains (1) summary
      cl21454
      Location:40 → 281
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    12. XM_038455715.1 → XP_038311643.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X2

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Conserved Domains (1) summary
      cl21454
      Location:40 → 236
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    13. XM_005633011.4 → XP_005633068.1  hydroxysteroid 11-beta-dehydrogenase 1-like protein isoform X3

      See identical proteins and their annotated locations for XP_005633068.1

      UniProtKB/TrEMBL
      A0A8C0TRL8, A0A8I3NQG9
      Conserved Domains (1) summary
      cl21454
      Location:27 → 223
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    Nucleotide Protein
    Heading Accession and Version

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