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    TPCN2 two pore segment channel 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 483683, updated on 5-Mar-2024

    Summary

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    Official Symbol
    TPCN2provided by VGNC
    Official Full Name
    two pore segment channel 2provided by VGNC
    Primary source
    VGNC:VGNC:47733
    See related
    Ensembl:ENSCAFG00845005889
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 18
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 18 NC_051822.1 (49592807..49659116, complement)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 18 NC_006600.4 (47525455..47591712, complement)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 18 NC_049239.1 (49371799..49438088, complement)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 18 NC_049278.1 (49039802..49105897, complement)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 18 NC_049759.1 (48625233..48691444, complement)

    Chromosome 18 - NC_051822.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119864250 Neighboring gene small integral membrane protein 38 Neighboring gene uncharacterized LOC102151204 Neighboring gene MAS related GPR family member F Neighboring gene MAS related GPR family member D

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables voltage-gated channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in lysosomal membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    two pore calcium channel protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051822.1 Reference ROS_Cfam_1.0

      Range
      49592807..49659116 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038424730.1 → XP_038280658.1  two pore calcium channel protein 2 isoform X2

      Conserved Domains (1) summary
      pfam00520
      Location:430 → 696
      Ion_trans; Ion transport protein

    2. XM_038424731.1 → XP_038280659.1  two pore calcium channel protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PMU7
      Conserved Domains (1) summary
      pfam00520
      Location:431 → 697
      Ion_trans; Ion transport protein

    3. XM_038424729.1 → XP_038280657.1  two pore calcium channel protein 2 isoform X1

      Conserved Domains (1) summary
      pfam00520
      Location:431 → 697
      Ion_trans; Ion transport protein

    4. XM_038424732.1 → XP_038280660.1  two pore calcium channel protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0KS73, A0A8I3N106
      Related
      ENSCAFP00845008120.1, ENSCAFT00845010449.1
      Conserved Domains (1) summary
      pfam00520
      Location:431 → 697
      Ion_trans; Ion transport protein

    RNA

    1. XR_005296609.1 RNA Sequence

    2. XR_005296608.1 RNA Sequence

      Related
      ENSCAFT00845010507.1

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049278.1 Alternate UMICH_Zoey_3.1

      Range
      49039802..49105897 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038500980.1 → XP_038356908.1  two pore calcium channel protein 2 isoform X5

    RNA

    1. XR_005339799.1 RNA Sequence

    2. XR_005339798.1 RNA Sequence

    3. XR_005339800.1 RNA Sequence

    4. XR_005339797.1 RNA Sequence

    5. XR_005339796.1 RNA Sequence

    6. XR_005339801.1 RNA Sequence

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049759.1 Alternate UNSW_CanFamBas_1.0

      Range
      48625233..48691444 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038627779.1 → XP_038483707.1  two pore calcium channel protein 2 isoform X2

    2. XM_038627780.1 → XP_038483708.1  two pore calcium channel protein 2 isoform X3

    3. XM_038627778.1 → XP_038483706.1  two pore calcium channel protein 2 isoform X1

    4. XM_038627781.1 → XP_038483709.1  two pore calcium channel protein 2 isoform X4

    RNA

    1. XR_005407631.1 RNA Sequence

    2. XR_005407630.1 RNA Sequence

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049239.1 Alternate UU_Cfam_GSD_1.0

      Range
      49371799..49438088 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038563658.1 → XP_038419586.1  two pore calcium channel protein 2 isoform X2

    2. XM_038563659.1 → XP_038419587.1  two pore calcium channel protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PMU7

    3. XM_038563657.1 → XP_038419585.1  two pore calcium channel protein 2 isoform X1

    4. XM_038563660.1 → XP_038419588.1  two pore calcium channel protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0KS73, A0A8P0PDI0
      Conserved Domains (1) summary
      pfam00520
      Location:431 → 697
      Ion_trans; Ion transport protein

    RNA

    1. XR_005373566.1 RNA Sequence

    2. XR_005373565.1 RNA Sequence

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006600.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      47525455..47591712 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038453771.1 → XP_038309699.1  two pore calcium channel protein 2 isoform X2

      Conserved Domains (1) summary
      pfam00520
      Location:430 → 696
      Ion_trans; Ion transport protein

    2. XM_038453772.1 → XP_038309700.1  two pore calcium channel protein 2 isoform X3

      UniProtKB/TrEMBL
      A0A8C0PMU7
      Conserved Domains (1) summary
      pfam00520
      Location:431 → 697
      Ion_trans; Ion transport protein

    3. XM_038453770.1 → XP_038309698.1  two pore calcium channel protein 2 isoform X1

      Conserved Domains (1) summary
      pfam00520
      Location:431 → 697
      Ion_trans; Ion transport protein

    4. XM_540804.7 → XP_540804.3  two pore calcium channel protein 2 isoform X4

      UniProtKB/TrEMBL
      A0A8C0KS73, A0A8P0PDI0
      Conserved Domains (1) summary
      pfam00520
      Location:431 → 697
      Ion_trans; Ion transport protein

    RNA

    1. XR_005311558.1 RNA Sequence

    2. XR_002616015.2 RNA Sequence

    Nucleotide Protein
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