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    GRB2 growth factor receptor bound protein 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 483312, updated on 5-Mar-2024

    Summary

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    Official Symbol
    GRB2provided by VGNC
    Official Full Name
    growth factor receptor bound protein 2provided by VGNC
    Primary source
    VGNC:VGNC:41472
    See related
    Ensembl:ENSCAFG00845026938
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs
    human mouse all
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    Genomic context

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    See GRB2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 9 NC_051813.1 (5778347..5852258)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 9 NC_006591.4 (5787497..5861309)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 9 NC_049230.1 (5988590..6061075)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 9 NC_049269.1 (5817381..5891089)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 9 NC_049750.1 (5927508..6001301)

    Chromosome 9 - NC_051813.1Genomic Context describing neighboring genes Neighboring gene CASK interacting protein 2 Neighboring gene tRNA splicing endonuclease subunit 54 Neighboring gene transmembrane protein 94 Neighboring gene uncharacterized LOC111097294 Neighboring gene uncharacterized LOC119873225 Neighboring gene solute carrier family 25 member 19 Neighboring gene U4 spliceosomal RNA Neighboring gene MIF4G domain containing Neighboring gene mitochondrial ribosomal protein S7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    growth factor receptor-bound protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051813.1 Reference ROS_Cfam_1.0

      Range
      5778347..5852258
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038675738.1 → XP_038531666.1  growth factor receptor-bound protein 2

      UniProtKB/TrEMBL
      A0A8C0M7T4, A0A8C0QST7, A0A8I3PT69
      Related
      ENSCAFP00845037253.1, ENSCAFT00845047482.1
      Conserved Domains (3) summary
      cd09941
      Location:56 → 150
      SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
      cd11946
      Location:1 → 56
      SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
      cd11949
      Location:160 → 212
      SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049269.1 Alternate UMICH_Zoey_3.1

      Range
      5817381..5891089
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038484928.1 → XP_038340856.1  growth factor receptor-bound protein 2

      Conserved Domains (3) summary
      cd09941
      Location:56 → 150
      SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
      cd11946
      Location:1 → 56
      SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
      cd11949
      Location:160 → 212
      SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049750.1 Alternate UNSW_CanFamBas_1.0

      Range
      5927508..6001301
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038610609.1 → XP_038466537.1  growth factor receptor-bound protein 2

      Conserved Domains (3) summary
      cd09941
      Location:56 → 150
      SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
      cd11946
      Location:1 → 56
      SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
      cd11949
      Location:160 → 212
      SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049230.1 Alternate UU_Cfam_GSD_1.0

      Range
      5988590..6061075
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038546617.1 → XP_038402545.1  growth factor receptor-bound protein 2

      UniProtKB/TrEMBL
      A0A8C0M7T4, A0A8C0QST7, A0A8I3PT69
      Conserved Domains (3) summary
      cd09941
      Location:56 → 150
      SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
      cd11946
      Location:1 → 56
      SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
      cd11949
      Location:160 → 212
      SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006591.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      5787497..5861309
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_540431.7 → XP_540431.2  growth factor receptor-bound protein 2

      See identical proteins and their annotated locations for XP_540431.2

      UniProtKB/TrEMBL
      A0A8C0M7T4, A0A8C0QST7, A0A8I3PT69
      Conserved Domains (3) summary
      cd09941
      Location:56 → 150
      SH2_Grb2_like; Src homology 2 domain found in Growth factor receptor-bound protein 2 (Grb2) and similar proteins
      cd11946
      Location:1 → 56
      SH3_GRB2_N; N-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
      cd11949
      Location:160 → 212
      SH3_GRB2_C; C-terminal Src homology 3 domain of Growth factor receptor-bound protein 2
    Nucleotide Protein
    Heading Accession and Version

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