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    UBR3 ubiquitin protein ligase E3 component n-recognin 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 478789, updated on 5-Mar-2024

    Summary

    Official Symbol
    UBR3provided by VGNC
    Official Full Name
    ubiquitin protein ligase E3 component n-recognin 3provided by VGNC
    Primary source
    VGNC:VGNC:53111
    See related
    Ensembl:ENSCAFG00845024347
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    ZNF650
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    chromosome: 36
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    106 current ROS_Cfam_1.0 (GCF_014441545.1) 36 NC_051840.1 (14617883..14845639)
    106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 36 NC_006618.4 (14510717..14734913)
    106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 36 NC_049257.1 (14804822..15030558)
    106 current UMICH_Zoey_3.1 (GCF_005444595.1) 36 NC_049296.1 (14700805..14925261)
    106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 36 NC_049777.1 (14693007..14919031)

    Chromosome 36 - NC_051840.1Genomic Context describing neighboring genes Neighboring gene Ewing sarcoma breakpoint region 1 pseudogene Neighboring gene methyltransferase 5, N6-adenosine Neighboring gene small RNA binding exonuclease protection factor La Neighboring gene uncharacterized LOC111094278 Neighboring gene uncharacterized LOC102157074 Neighboring gene myosin IIIB

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in ubiquitin-dependent protein catabolic process via the N-end rule pathway IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    part_of ubiquitin ligase complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase UBR3
    Names
    ubiquitin protein ligase E3 component n-recognin 3 (putative)
    zinc finger protein 650
    XP_038302933.1
    XP_038302934.1
    XP_038302935.1
    XP_038302936.1
    XP_038302937.1
    XP_038302938.1
    XP_038302939.1
    XP_038319425.1
    XP_038319426.1
    XP_038319427.1
    XP_038319428.1
    XP_038319429.1
    XP_038319430.1
    XP_038319431.1
    XP_038377008.1
    XP_038377009.1
    XP_038377010.1
    XP_038377011.1
    XP_038377012.1
    XP_038377013.1
    XP_038377014.1
    XP_038440710.1
    XP_038440711.1
    XP_038440712.1
    XP_038440713.1
    XP_038440714.1
    XP_038440715.1
    XP_038440716.1
    XP_038505125.1
    XP_038505126.1
    XP_038505127.1
    XP_038505128.1
    XP_038505129.1
    XP_038505130.1
    XP_038505131.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ROS_Cfam_1.0

    Genomic

    1. NC_051840.1 Reference ROS_Cfam_1.0

      Range
      14617883..14845639
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038447005.1XP_038302933.1  E3 ubiquitin-protein ligase UBR3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14421888
      PRT6_C; Proteolysis_6 C-terminal
    2. XM_038447007.1XP_038302935.1  E3 ubiquitin-protein ligase UBR3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14381884
      PRT6_C; Proteolysis_6 C-terminal
    3. XM_038447008.1XP_038302936.1  E3 ubiquitin-protein ligase UBR3 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14311877
      PRT6_C; Proteolysis_6 C-terminal
    4. XM_038447009.1XP_038302937.1  E3 ubiquitin-protein ligase UBR3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0MVK6, A0A8I3PVZ1
      Related
      ENSCAFP00845033732.1, ENSCAFT00845043023.1
      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14271873
      PRT6_C; Proteolysis_6 C-terminal
    5. XM_038447006.1XP_038302934.1  E3 ubiquitin-protein ligase UBR3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12451383
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14411887
      PRT6_C; Proteolysis_6 C-terminal
    6. XM_038447011.1XP_038302939.1  E3 ubiquitin-protein ligase UBR3 isoform X7

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12341372
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14301876
      PRT6_C; Proteolysis_6 C-terminal
    7. XM_038447010.1XP_038302938.1  E3 ubiquitin-protein ligase UBR3 isoform X6

      Conserved Domains (2) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    Alternate UMICH_Zoey_3.1

    Genomic

    1. NC_049296.1 Alternate UMICH_Zoey_3.1

      Range
      14700805..14925261
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038521080.1XP_038377008.1  E3 ubiquitin-protein ligase UBR3 isoform X1

      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14421888
      PRT6_C; Proteolysis_6 C-terminal
    2. XM_038521082.1XP_038377010.1  E3 ubiquitin-protein ligase UBR3 isoform X3

      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14381884
      PRT6_C; Proteolysis_6 C-terminal
    3. XM_038521083.1XP_038377011.1  E3 ubiquitin-protein ligase UBR3 isoform X4

      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14311877
      PRT6_C; Proteolysis_6 C-terminal
    4. XM_038521084.1XP_038377012.1  E3 ubiquitin-protein ligase UBR3 isoform X5

      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14271873
      PRT6_C; Proteolysis_6 C-terminal
    5. XM_038521081.1XP_038377009.1  E3 ubiquitin-protein ligase UBR3 isoform X2

      Conserved Domains (3) summary
      cd16483
      Location:12451383
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14411887
      PRT6_C; Proteolysis_6 C-terminal
    6. XM_038521086.1XP_038377014.1  E3 ubiquitin-protein ligase UBR3 isoform X7

      Conserved Domains (3) summary
      cd16483
      Location:12341372
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14301876
      PRT6_C; Proteolysis_6 C-terminal
    7. XM_038521085.1XP_038377013.1  E3 ubiquitin-protein ligase UBR3 isoform X6

      Conserved Domains (2) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    Alternate UNSW_CanFamBas_1.0

    Genomic

    1. NC_049777.1 Alternate UNSW_CanFamBas_1.0

      Range
      14693007..14919031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038649197.1XP_038505125.1  E3 ubiquitin-protein ligase UBR3 isoform X1

      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14421888
      PRT6_C; Proteolysis_6 C-terminal
    2. XM_038649199.1XP_038505127.1  E3 ubiquitin-protein ligase UBR3 isoform X3

      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14381884
      PRT6_C; Proteolysis_6 C-terminal
    3. XM_038649200.1XP_038505128.1  E3 ubiquitin-protein ligase UBR3 isoform X4

      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14311877
      PRT6_C; Proteolysis_6 C-terminal
    4. XM_038649201.1XP_038505129.1  E3 ubiquitin-protein ligase UBR3 isoform X5

      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14271873
      PRT6_C; Proteolysis_6 C-terminal
    5. XM_038649198.1XP_038505126.1  E3 ubiquitin-protein ligase UBR3 isoform X2

      Conserved Domains (3) summary
      cd16483
      Location:12451383
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14411887
      PRT6_C; Proteolysis_6 C-terminal
    6. XM_038649203.1XP_038505131.1  E3 ubiquitin-protein ligase UBR3 isoform X7

      Conserved Domains (3) summary
      cd16483
      Location:12341372
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14301876
      PRT6_C; Proteolysis_6 C-terminal
    7. XM_038649202.1XP_038505130.1  E3 ubiquitin-protein ligase UBR3 isoform X6

      Conserved Domains (2) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    Alternate UU_Cfam_GSD_1.0

    Genomic

    1. NC_049257.1 Alternate UU_Cfam_GSD_1.0

      Range
      14804822..15030558
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038584782.1XP_038440710.1  E3 ubiquitin-protein ligase UBR3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14421888
      PRT6_C; Proteolysis_6 C-terminal
    2. XM_038584784.1XP_038440712.1  E3 ubiquitin-protein ligase UBR3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14381884
      PRT6_C; Proteolysis_6 C-terminal
    3. XM_038584785.1XP_038440713.1  E3 ubiquitin-protein ligase UBR3 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14311877
      PRT6_C; Proteolysis_6 C-terminal
    4. XM_038584786.1XP_038440714.1  E3 ubiquitin-protein ligase UBR3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0MVK6, A0A8I3PVZ1
      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14271873
      PRT6_C; Proteolysis_6 C-terminal
    5. XM_038584783.1XP_038440711.1  E3 ubiquitin-protein ligase UBR3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12451383
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14411887
      PRT6_C; Proteolysis_6 C-terminal
    6. XM_038584788.1XP_038440716.1  E3 ubiquitin-protein ligase UBR3 isoform X7

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12341372
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14301876
      PRT6_C; Proteolysis_6 C-terminal
    7. XM_038584787.1XP_038440715.1  E3 ubiquitin-protein ligase UBR3 isoform X6

      Conserved Domains (2) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)

    Alternate Dog10K_Boxer_Tasha Primary Assembly

    Genomic

    1. NC_006618.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

      Range
      14510717..14734913
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_038463497.1XP_038319425.1  E3 ubiquitin-protein ligase UBR3 isoform X1

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14421888
      PRT6_C; Proteolysis_6 C-terminal
    2. XM_038463499.1XP_038319427.1  E3 ubiquitin-protein ligase UBR3 isoform X3

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14381884
      PRT6_C; Proteolysis_6 C-terminal
    3. XM_038463500.1XP_038319428.1  E3 ubiquitin-protein ligase UBR3 isoform X4

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14311877
      PRT6_C; Proteolysis_6 C-terminal
    4. XM_038463501.1XP_038319429.1  E3 ubiquitin-protein ligase UBR3 isoform X5

      UniProtKB/TrEMBL
      A0A8C0MVK6, A0A8I3PVZ1
      Conserved Domains (3) summary
      cd16483
      Location:12351373
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14271873
      PRT6_C; Proteolysis_6 C-terminal
    5. XM_038463498.1XP_038319426.1  E3 ubiquitin-protein ligase UBR3 isoform X2

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12451383
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14411887
      PRT6_C; Proteolysis_6 C-terminal
    6. XM_038463503.1XP_038319431.1  E3 ubiquitin-protein ligase UBR3 isoform X7

      UniProtKB/TrEMBL
      A0A8C0MVK6
      Conserved Domains (3) summary
      cd16483
      Location:12341372
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)
      pfam18995
      Location:14301876
      PRT6_C; Proteolysis_6 C-terminal
    7. XM_038463502.1XP_038319430.1  E3 ubiquitin-protein ligase UBR3 isoform X6

      Conserved Domains (2) summary
      cd16483
      Location:12461384
      RING-H2_UBR3; RING finger, H2 subclass, found in ubiquitin-protein ligase E3-alpha-3 (UBR3) and similar proteins
      pfam02207
      Location:121188
      zf-UBR; Putative zinc finger in N-recognin (UBR box)