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    MOS MOS proto-oncogene, serine/threonine kinase [ Bos taurus (cattle) ]

    Gene ID: 444869, updated on 5-Mar-2024

    Summary

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    Official Symbol
    MOSprovided by VGNC
    Official Full Name
    MOS proto-oncogene, serine/threonine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:31563
    See related
    BGD:BT30082; Ensembl:ENSBTAG00000019145
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    C-MOS
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 14
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 14 NC_037341.1 (23299079..23300457, complement)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U54 Neighboring gene ribosomal protein S20 Neighboring gene U1 spliceosomal RNA Neighboring gene PLAG1 zinc finger Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037341.1 Chromosome 14 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The effects of demecolcine, alone or in combination with sucrose on bovine oocyte protrusion rate, MAPK1 protein level and c-mos gene expression level. Gao Y, et al. Cell Physiol Biochem, 2014. PMID 25500918
    2. The thyroglobulin gene is syntenic with the MYC and MOS protooncogenes and carbonic anhydrase II and maps to chromosome 14 in cattle. Threadgill DW, et al. Cytogenet Cell Genet, 1990. PMID 2108842
    3. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The present results suggest that demecolcine might contribute to the activation of the Mos/MAPK pathway and affect spindle structure
      Title: The effects of demecolcine, alone or in combination with sucrose on bovine oocyte protrusion rate, MAPK1 protein level and c-mos gene expression level.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proto-oncogene serine/threonine-protein kinase mos
    Names
    oocyte maturation factor Mos
    protein kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      23299079..23300457 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_002692654.5 → XP_002692700.1  proto-oncogene serine/threonine-protein kinase mos

      See identical proteins and their annotated locations for XP_002692700.1

      UniProtKB/TrEMBL
      F6RCH9
      Related
      ENSBTAP00000025483.5, ENSBTAT00000025483.6
      Conserved Domains (2) summary
      smart00220
      Location:58 → 322
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd13979
      Location:52 → 322
      STKc_Mos; Catalytic domain of the Serine/Threonine kinase, Oocyte maturation factor Mos
    Nucleotide Protein Strain
    Heading Accession and Version

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