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    TTK TTK protein kinase [ Gallus gallus (chicken) ]

    Gene ID: 421849, updated on 5-Mar-2024

    Summary

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    Symbol
    TTKprovided by CGNC
    Full Name
    TTK protein kinaseprovided by CGNC
    Primary source
    CGNC:11840
    See related
    Ensembl:ENSGALG00010002437
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (78897877..78930670, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (78690177..78722959, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene branched chain keto acid dehydrogenase E1 subunit beta Neighboring gene uncharacterized LOC121110234 Neighboring gene microRNA 1712 Neighboring gene ELOVL fatty acid elongase 4 Neighboring gene SH3 domain binding glutamate rich protein like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene pathways and cell cycle-related genes in cultured avian primordial germ cells. Rengaraj D, et al. Poult Sci, 2012 Dec. PMID 23155027

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine/tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in meiotic spindle assembly checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in mitotic spindle assembly checkpoint signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein localization to kinetochore IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    dual specificity protein kinase TTK

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      78897877..78930670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046939018.1 → XP_046794974.1  dual specificity protein kinase TTK

      UniProtKB/TrEMBL
      A0A8V0XCY6

    2. XM_419867.8 → XP_419867.5  dual specificity protein kinase TTK

      UniProtKB/TrEMBL
      A0A8V0XCY6
      Related
      ENSGALP00010003457.1, ENSGALT00010005618.1
      Conserved Domains (1) summary
      cd14131
      Location:541 → 810
      PKc_Mps1; Catalytic domain of the Dual-specificity Mitotic checkpoint protein kinase, Monopolar spindle 1 (also called TTK)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      78690177..78722959 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046914648.1 → XP_046770604.1  dual specificity protein kinase TTK

    2. XM_040666953.2 → XP_040522887.1  dual specificity protein kinase TTK

      Conserved Domains (1) summary
      cd14131
      Location:541 → 810
      PKc_Mps1; Catalytic domain of the Dual-specificity Mitotic checkpoint protein kinase, Monopolar spindle 1 (also called TTK)
    Nucleotide Protein
    Heading Accession and Version

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