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    FH fumarate hydratase [ Gallus gallus (chicken) ]

    Gene ID: 420969, updated on 11-Apr-2024

    Summary

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    Official Symbol
    FHprovided by CGNC
    Official Full Name
    fumarate hydrataseprovided by CGNC
    Primary source
    CGNC:9939
    See related
    Ensembl:ENSGALG00010009197
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (85267730..85282102, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (85339949..85355460, complement)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene BCL2 associated athanogene 1 Neighboring gene charged multivesicular body protein 5 Neighboring gene succinate dehydrogenase complex flavoprotein subunit A Neighboring gene coiled-coil domain containing 127

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Conserved BK channel-protein interactions reveal signals relevant to cell death and survival. Sokolowski B, et al. PLoS One, 2011. PMID 22174833, Free PMC Article
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables fumarate hydratase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fumarate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in malate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tricarboxylic acid cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of tricarboxylic acid cycle heteromeric enzyme complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    fumarate hydratase, mitochondrial
    NP_001006382.1
    NP_001383574.1
    NP_001383575.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006382.2 → NP_001006382.1  fumarate hydratase, mitochondrial isoform a

      See identical proteins and their annotated locations for NP_001006382.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000041
      UniProtKB/TrEMBL
      A0A8V0Y9B0, Q5ZLD1
      Related
      ENSGALP00010012562.1, ENSGALT00010021940.1
      Conserved Domains (2) summary
      cd01362
      Location:48 → 503
      Fumarase_classII; Class II fumarases
      PRK00485
      Location:46 → 507
      fumC; fumarate hydratase; Reviewed

    2. NM_001396645.1 → NP_001383574.1  fumarate hydratase, mitochondrial isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000041
      UniProtKB/TrEMBL
      A0A8V0Y9B0
      Conserved Domains (1) summary
      PRK00485
      Location:2 → 434
      fumC; fumarate hydratase; Reviewed

    3. NM_001396646.1 → NP_001383575.1  fumarate hydratase, mitochondrial isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000041
      UniProtKB/TrEMBL
      A0A8V0Y9B0
      Conserved Domains (1) summary
      PRK00485
      Location:2 → 434
      fumC; fumarate hydratase; Reviewed

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      85267730..85282102 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      85339949..85355460 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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