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    PPP1R8 protein phosphatase 1 regulatory subunit 8 [ Gallus gallus (chicken) ]

    Gene ID: 419564, updated on 3-Apr-2024

    Summary

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    Official Symbol
    PPP1R8provided by CGNC
    Official Full Name
    protein phosphatase 1 regulatory subunit 8provided by CGNC
    Primary source
    CGNC:463
    See related
    Ensembl:ENSGALG00010012709
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 23
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 23 NC_052554.1 (1800338..1817889)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 23 NC_052595.1 (1568482..1586074)

    Chromosome 23 - NC_052554.1Genomic Context describing neighboring genes Neighboring gene Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 Neighboring gene guanylate binding protein 1 Neighboring gene syntaxin 12 Neighboring gene small Cajal body-specific RNA 1 Neighboring gene thymocyte selection associated family member 2 Neighboring gene replication protein A2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nuclear speck IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    nuclear inhibitor of protein phosphatase 1
    Names
    protein phosphatase 1, regulatory (inhibitor) subunit 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001030891.3 → NP_001026062.2  nuclear inhibitor of protein phosphatase 1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000339
      UniProtKB/TrEMBL
      A0A8V0YFH1
      Related
      ENSGALP00010017643.1, ENSGALT00010030422.1
      Conserved Domains (2) summary
      cd00060
      Location:30 → 122
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam11945
      Location:101 → 247
      WASH_WAHD; WAHD domain of WASH complex

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052554.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      1800338..1817889
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025142981.3 → XP_024998749.1  nuclear inhibitor of protein phosphatase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0YFH1
      Conserved Domains (2) summary
      cd00060
      Location:30 → 93
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam11945
      Location:105 → 250
      WASH_WAHD; WAHD domain of WASH complex

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052595.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      1568482..1586074
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046931947.1 → XP_046787903.1  nuclear inhibitor of protein phosphatase 1 isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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