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    SLX4 SLX4 structure-specific endonuclease subunit homolog [ Gallus gallus (chicken) ]

    Gene ID: 416665, updated on 5-Mar-2024

    Summary

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    Official Symbol
    SLX4provided by CGNC
    Official Full Name
    SLX4 structure-specific endonuclease subunit homologprovided by CGNC
    Primary source
    CGNC:5769
    See related
    Ensembl:ENSGALG00010016341
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    BTBD12
    Orthologs
    human mouse all
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    Genomic context

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    See SLX4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (12444459..12472469, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (12440004..12468001, complement)

    Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054646 Neighboring gene zinc finger with KRAB and SCAN domains 7 Neighboring gene TNF receptor associated protein 1 Neighboring gene CREB binding protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway. Yamamoto KN, et al. Proc Natl Acad Sci U S A, 2011 Apr 19. PMID 21464321, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables enzyme binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in interstrand cross-link repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in meiotic DNA double-strand break processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in resolution of meiotic recombination intermediates IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Slx1-Slx4 complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    structure-specific endonuclease subunit SLX4
    Names
    BTB (POZ) domain containing 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      12444459..12472469 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040647711.2 → XP_040503645.1  structure-specific endonuclease subunit SLX4 isoform X3

      UniProtKB/TrEMBL
      A0A8V0YNU3
      Related
      ENSGALP00010022679.1, ENSGALT00010039319.1
      Conserved Domains (1) summary
      cd18288
      Location:520 → 635
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

    2. XM_015294632.4 → XP_015150118.2  structure-specific endonuclease subunit SLX4 isoform X2

      Conserved Domains (1) summary
      cd18288
      Location:642 → 757
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

    3. XM_004945379.5 → XP_004945436.2  structure-specific endonuclease subunit SLX4 isoform X1

      Conserved Domains (1) summary
      cd18288
      Location:644 → 759
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

    4. XM_046900728.1 → XP_046756684.1  structure-specific endonuclease subunit SLX4 isoform X1

    5. XM_015294630.4 → XP_015150116.2  structure-specific endonuclease subunit SLX4 isoform X1

      Conserved Domains (1) summary
      cd18288
      Location:644 → 759
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      12440004..12468001 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040684152.2 → XP_040540086.1  structure-specific endonuclease subunit SLX4 isoform X3

      Conserved Domains (1) summary
      cd18288
      Location:520 → 635
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

    2. XM_040684151.2 → XP_040540085.1  structure-specific endonuclease subunit SLX4 isoform X2

      Conserved Domains (1) summary
      cd18288
      Location:642 → 757
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

    3. XM_040684146.2 → XP_040540080.1  structure-specific endonuclease subunit SLX4 isoform X1

      Conserved Domains (1) summary
      cd18288
      Location:644 → 759
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

    4. XM_040684150.2 → XP_040540084.1  structure-specific endonuclease subunit SLX4 isoform X1

      Conserved Domains (1) summary
      cd18288
      Location:644 → 759
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4

    5. XM_040684149.2 → XP_040540083.1  structure-specific endonuclease subunit SLX4 isoform X1

      Conserved Domains (1) summary
      cd18288
      Location:644 → 759
      BTB_POZ_BTBD12_SLX4; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Structure-specific endonuclease subunit SLX4
    Nucleotide Protein Strain
    Heading Accession and Version

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