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    TXN thioredoxin [ Gallus gallus (chicken) ]

    Gene ID: 396437, updated on 5-Mar-2024

    Summary

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    Official Symbol
    TXNprovided by CGNC
    Official Full Name
    thioredoxinprovided by CGNC
    Primary source
    CGNC:49804
    See related
    Ensembl:ENSGALG00010005495
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Z
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (67208387..67213741, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (67208387..67213741, complement)

    Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene structural maintenance of chromosomes 2 Neighboring gene Prostaglandin reductase 1 Neighboring gene E3 ubiquitin-protein ligase Topors-like Neighboring gene uncharacterized LOC107052410 Neighboring gene uncharacterized LOC121108563 Neighboring gene sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Selenium deficiency-induced thioredoxin suppression and thioredoxin knock down disbalanced insulin responsiveness in chicken cardiomyocytes through PI3K/Akt pathway inhibition. Yang J, et al. Cell Signal, 2017 Oct. PMID 28734787
    2. Isolation of a chicken thioredoxin cDNA clone. Thioredoxin mRNA is differentially expressed in normal and Rous sarcoma virus-transformed chicken embryo fibroblasts. Jones SW, et al. J Biol Chem, 1988 Jul 15. PMID 2838473
    3. Proteomic studies of Syk-interacting proteins using a novel amine-specific isotope tag and GFP nanotrap. Galan JA, et al. J Am Soc Mass Spectrom, 2011 Feb. PMID 21472591, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These findings point out that Txn system can redox regulate the insulin dependent glucose metabolism in heart and is essential for cell vitality.
      Title: Selenium deficiency-induced thioredoxin suppression and thioredoxin knock down disbalanced insulin responsiveness in chicken cardiomyocytes through PI3K/Akt pathway inhibition.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein-disulfide reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    thioredoxin
    Names
    trx

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205453.2 → NP_990784.1  thioredoxin

      See identical proteins and their annotated locations for NP_990784.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000095
      UniProtKB/Swiss-Prot
      P08629
      UniProtKB/TrEMBL
      A0A8V0XLY1
      Related
      ENSGALP00010007700.1, ENSGALT00010013138.1
      Conserved Domains (1) summary
      cd02947
      Location:9 → 102
      TRX_family; TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      67208387..67213741 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      67208387..67213741 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P08629.2 GenPept UniProtKB/Swiss-Prot:P08629

    Gene LinkOut

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