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    HPSE heparanase [ Gallus gallus (chicken) ]

    Gene ID: 373981, updated on 5-Mar-2024

    Summary

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    Official Symbol
    HPSEprovided by CGNC
    Official Full Name
    heparanaseprovided by CGNC
    Primary source
    CGNC:8508
    See related
    Ensembl:ENSGALG00010002522
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 4
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (46019650..46024543, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (45959673..45964557, complement)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene PLAC8 like 2 Neighboring gene coenzyme Q2, polyprenyltransferase Neighboring gene mitochondrial ribosomal protein S18C Neighboring gene helicase, POLQ-like Neighboring gene family with sequence similarity 175 member A Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 5 like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression pattern and secretion of human and chicken heparanase are determined by their signal peptide sequence. Goldshmidt O, et al. J Biol Chem, 2001 Aug 3. PMID 11387326
    2. Heparanase mediates cell adhesion independent of its enzymatic activity. Goldshmidt O, et al. FASEB J, 2003 Jun. PMID 12773484
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables hydrolase activity, acting on glycosyl bonds IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular matrix IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heparanase
    NP_989498.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204167.2 → NP_989498.2  heparanase precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000073
      UniProtKB/Swiss-Prot
      Q90YK5
      Related
      ENSGALP00010003601.1, ENSGALT00010005798.1

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      46019650..46024543 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      45959673..45964557 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q90YK5.1 GenPept UniProtKB/Swiss-Prot:Q90YK5

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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