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    NDUFA6 NADH:ubiquinone oxidoreductase subunit A6 [ Bos taurus (cattle) ]

    Gene ID: 327670, updated on 5-Mar-2024

    Summary

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    Official Symbol
    NDUFA6provided by VGNC
    Official Full Name
    NADH:ubiquinone oxidoreductase subunit A6provided by VGNC
    Primary source
    VGNC:VGNC:31950
    See related
    BGD:BT21801; Ensembl:ENSBTAG00000009509
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    B14
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 5
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 5 NC_037332.1 (113045787..113056779, complement)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene PH domain containing endocytic trafficking adaptor 2 Neighboring gene single-pass membrane protein with aspartate rich tail 1 Neighboring gene uncharacterized LOC785804 Neighboring gene cytochrome P450 family 2 subfamily D member 43

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037332.1 Chromosome 5 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry. Murray J, et al. J Biol Chem, 2003 Sep 26. PMID 12857734
    2. Resolution of the membrane domain of bovine complex I into subcomplexes: implications for the structural organization of the enzyme. Sazanov LA, et al. Biochemistry, 2000 Jun 20. PMID 10852722
    3. Subunit analysis of bovine heart complex I by reversed-phase high-performance liquid chromatography, electrospray ionization-tandem mass spectrometry, and matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry. Lemma-Gray P, et al. Anal Biochem, 2008 Nov 15. PMID 18721790, Free PMC Article
    4. Sequences of 20 subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Application of a novel strategy for sequencing proteins using the polymerase chain reaction. Walker JE, et al. J Mol Biol, 1992 Aug 20. PMID 1518044
    5. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of mitochondrial respiratory chain complex I IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
    Names
    CI-B14
    NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa
    NADH-ubiquinone oxidoreductase B14 subunit
    complex I-B14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175791.2 → NP_786985.1  NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

      See identical proteins and their annotated locations for NP_786985.1

      Status: PROVISIONAL

      Source sequence(s)
      X63211
      UniProtKB/Swiss-Prot
      Q02366, Q3T0E4
      UniProtKB/TrEMBL
      A0A452DIB4
      Related
      ENSBTAP00000012512.6, ENSBTAT00000012512.7
      Conserved Domains (1) summary
      cd20266
      Location:25 → 99
      Complex1_LYR_NDUFA6_LYRM6; LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (NDUFA6) and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      113045787..113056779 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q02366.2 GenPept UniProtKB/Swiss-Prot:Q02366

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