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    Imp3 IMP U3 small nucleolar ribonucleoprotein 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 315697, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Imp3provided by RGD
    Official Full Name
    IMP U3 small nucleolar ribonucleoprotein 3provided by RGD
    Primary source
    RGD:1306825
    See related
    AllianceGenome:RGD:1306825
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1306825
    Summary
    Predicted to enable snoRNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Mpp10 complex and small-subunit processome. Orthologous to human IMP3 (IMP U3 small nucleolar ribonucleoprotein 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    8q24
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (66235498..66236386)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (57339528..57340416)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (61607021..61607909)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene sorting nexin 33 Neighboring gene ribosomal protein S15a like 7 Neighboring gene snurportin 1 Neighboring gene uncharacterized LOC103693102 Neighboring gene protein tyrosine phosphatase, non-receptor type 9 Neighboring gene uncharacterized LOC102553607

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The human Imp3 and Imp4 proteins form a ternary complex with hMpp10, which only interacts with the U3 snoRNA in 60-80S ribonucleoprotein complexes. Granneman S, et al. Nucleic Acids Res, 2003 Apr 1. PMID 12655004, Free PMC Article
    2. The roles of SSU processome components and surveillance factors in the initial processing of human ribosomal RNA. Sloan KE, et al. RNA, 2014 Apr. PMID 24550520, Free PMC Article
    3. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889
    4. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Castello A, et al. Cell, 2012 Jun 8. PMID 22658674
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables snoRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within rRNA processing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ribosomal small subunit biogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of Mpp10 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Mpp10 complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of preribosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    U3 small nucleolar ribonucleoprotein protein IMP3
    Names
    IMP3, U3 small nucleolar ribonucleoprotein, homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108152.1 → NP_001101622.1  U3 small nucleolar ribonucleoprotein protein IMP3

      See identical proteins and their annotated locations for NP_001101622.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473975
      UniProtKB/TrEMBL
      B2RZ12
      Conserved Domains (1) summary
      COG0522
      Location:1 → 168
      RpsD; Ribosomal protein S4 or related protein [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      66235498..66236386
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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